| Gene ID | Transcript ID | Common Gene Name | # of miRNA targets for specified miRNAs | Chromosome | Strand Direction | Transcript Link to view miRNA target predictions | Gene Link | Description |
|---|---|---|---|---|---|---|---|---|
| AH9.4 | AH9.4 | AH9.4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| B0395.1 | B0395.1 | nhx-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | nhx-1 encodes a sodium/proton exchanger expressed intracellularly within hypodermal and muscle cells. NHX-1 is required for embryonic viability, and is thought to prevent intracellular acidification by catalysing the electroneutral exchange of vesicular sodium for an intracellular proton. [Source: WormBase] |
| B0395.3 | B0395.3.1 | B0395.3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | B0395.3 is orthologous to the human gene CHOLINE ACETYLTRANSFERASE ISOFORM R (CHAT. OMIM:118490), which when mutated leads to disease. [Source: WormBase] |
| B0395.3 | B0395.3.2 | B0395.3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | B0395.3 is orthologous to the human gene CHOLINE ACETYLTRANSFERASE ISOFORM R (CHAT. OMIM:118490), which when mutated leads to disease. [Source: WormBase] |
| B0403.2 | B0403.2 | ubc-17 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0403.5 | B0403.5 | B0403.5 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0416.5 | B0416.5a | B0416.5 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| B0563.2 | B0563.2 | tsp-11 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0563.4 | B0563.4.1 | tmbi-4 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0563.4 | B0563.4.2 | tmbi-4 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C02B8.6 | C02B8.6 | C02B8.6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C02C6.1 | C02C6.1a | dyn-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | dyn-1 encodes the C. elegans ortholog of the dynamin GTPase. dyn-1 activity is required for endocytosis, synaptic vesicle recycling, cytokinesis, and the CED-1 pathway that regulates engulfment and degradation of apoptotic cells. mutations in dyn-1 affect locomotion, egg-laying, defecation, and embryonic development, indicating that dyn-1's endocytic function is required for a number of diverse processes. dyn-1 reporter fusion constructs are expressed in motor neurons, intestinal cells, and pharyngeal muscle. [Source: WormBase] |
| C02C6.1 | C02C6.1b | dyn-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | dyn-1 encodes the C. elegans ortholog of the dynamin GTPase. dyn-1 activity is required for endocytosis, synaptic vesicle recycling, cytokinesis, and the CED-1 pathway that regulates engulfment and degradation of apoptotic cells. mutations in dyn-1 affect locomotion, egg-laying, defecation, and embryonic development, indicating that dyn-1's endocytic function is required for a number of diverse processes. dyn-1 reporter fusion constructs are expressed in motor neurons, intestinal cells, and pharyngeal muscle. [Source: WormBase] |
| C02D4.2 | C02D4.2e | ser-2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase] |
| C02H7.1 | C02H7.1 | dyf-11 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | dyf-11 encodes a conserved protein orthologous to the human microtubule-binding protein MIP-T3 and that contains a lysine-rich region and a C-terminal coiled-coil domain present in a number of intraflagellar transport (IFT) complex B proteins. DYF-11 activity is required continuously in sensory neurons for formation of medial and distal ciliary segments and thus, for normal sensory cilium morphology and function and chemotaxis. a dyf-11::gfp promoter fusion is expressed in all ciliated sensory neurons as well as in the AQR, PQR, ADE, and PDR neurons. a DYF-11::GFP protein fusion is detected throughout the cilium and appears to localize to IFT-B particles in a manner consistent with an early role in IFT-B particle assembly. dyf-11 expression in ciliated neurons is dependent upon the presence of the DAF-19 RFX transcription factor. [Source: WormBase] |
| C03A3.2 | C03A3.2.1 | C03A3.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C03A3.2 | C03A3.2.2 | C03A3.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C03B1.5 | C03B1.5 | C03B1.5 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C04A11.4 | C04A11.4 | adm-2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | adm-2 encodes a protein containing a snake venom disintegrin-domain and a metalloprotease-like domain (i.e., a protein of the ADAM family). like ADM-1, ADM-2 is homologous to a mammalian sperm glycoprotein (PH-30/fertilin) implicated in sperm-egg fusion, and ADM-2 might thus be a fusogenic protein mediating the merging of plasma membranes during development. [Source: WormBase] |
| C04C11.2 | C04C11.2.1 | arrd-25 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C04C11.2 | C04C11.2.2 | arrd-25 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C04F6.3 | C04F6.3.1 | cht-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | cht-1 encodes a chitinase orthologous to human chitinase-1 (OMIM:600031, mutations are associated with chitotriosidase deficiency). CHT-1 is predicted to function as an extracellular O-glycosyl hydrolase that hydrolyzes the glycosidic bond between two or more carbohydrates. in C. elegans, CHT-1 may play a role in embryogenesis, and may also be required for cuticle degradation during molting and degradation of chitin-containing pathogens as part of a host defense mechanism. [Source: WormBase] |
| C04F6.3 | C04F6.3.2 | cht-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | cht-1 encodes a chitinase orthologous to human chitinase-1 (OMIM:600031, mutations are associated with chitotriosidase deficiency). CHT-1 is predicted to function as an extracellular O-glycosyl hydrolase that hydrolyzes the glycosidic bond between two or more carbohydrates. in C. elegans, CHT-1 may play a role in embryogenesis, and may also be required for cuticle degradation during molting and degradation of chitin-containing pathogens as part of a host defense mechanism. [Source: WormBase] |
| C05A9.1 | C05A9.1a | pgp-5 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | pgp-5 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily. by homology, PGP-5 is predicted to function as an ATP-dependent efflux pump that protects C. elegans by exporting exogenous toxins. however, as loss of pgp-5 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of PGP-5 in C. elegans development and/or behavior is not yet known. [Source: WormBase] |
| C05A9.1 | C05A9.1b | pgp-5 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | pgp-5 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily. by homology, PGP-5 is predicted to function as an ATP-dependent efflux pump that protects C. elegans by exporting exogenous toxins. however, as loss of pgp-5 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of PGP-5 in C. elegans development and/or behavior is not yet known. [Source: WormBase] |
| C05C9.1 | C05C9.1 | C05C9.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C05D9.2 | C05D9.2.1 | lmp-2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | lmp-2 encodes a transmembrane protein that is one of two C. elegans LAMP (lysosomal associated membrane glycoprotein) homologs. [Source: WormBase] |
| C05D9.2 | C05D9.2.2 | lmp-2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | lmp-2 encodes a transmembrane protein that is one of two C. elegans LAMP (lysosomal associated membrane glycoprotein) homologs. [Source: WormBase] |
| C05D9.2 | C05D9.2.3 | lmp-2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | lmp-2 encodes a transmembrane protein that is one of two C. elegans LAMP (lysosomal associated membrane glycoprotein) homologs. [Source: WormBase] |
| C05E11.4 | C05E11.4 | amt-1 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | amt-1 encodes a transmembrane transporter that by homology, is predicted to transport ammonium ions across the plasma membrane. as loss of amt-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of AMT-1 in C. elegans development and/or behavior is not yet known. [Source: WormBase] |
| C05E7.1 | C05E7.1 | C05E7.1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C05E7.2 | C05E7.2 | C05E7.2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C05G5.1 | C05G5.1 | C05G5.1 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C05G5.4 | C05G5.4.1 | C05G5.4 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C05G5.4 | C05G5.4.2 | C05G5.4 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C06G1.1 | C06G1.1a | C06G1.1 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C06G1.1 | C06G1.1b | C06G1.1 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C06G1.4 | C06G1.4.1 | ain-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | ain-1 encodes an unfamiliar protein synergistically required, with LIN-31, for the normal timing of vulval differentiation, independently of LET-60/RAS, and parallel to or downstream of LIN-14/LIN-28/HBL-1. AIN-1 is expressed in cytoplasmic foci (that are probably P bodies) in several tissues, including vulval precursor cells and neurons. AIN-1 coimmunoprecipitates with DCR-1 and ALG-1, also binds ALG-1 in vitro, and does not require DNA or RNA for its binding. in vivo, AIN-1 targets ALG-1 to cytoplasmic foci, in which it colocalizes with DCAP-2. AIN-1 is likely to be a RISC component, since anti-AIN-1 antibodies precipitate 29 different miRNAs, including mir-2, mir-52, mir-58, mir-71, mir-77, and mir-239a. ain-1(ku322) mutants are essentially wild-type, except for sporadically gapped alae and excess seam cell nuclei arising from retarded seam cell fusion. more prominently, ain-1(ku322) suppresses the multivulva phenotype of lin-31(n1053) mutations, while strongly enhancing lin-31(n1053)'s egg-laying defect. the cellular basis of lin-31(n1053).ain-1(ku322) phenotypes is a delay in vulval development in L4 larvae not seen with either mutation alone. ain-1(ku322) has no effect on let-60(n1046) or lin-3(e1275) mutations. ain-1(ku322) suppresses the precocious vulval development of lin-14(RNAi), lin-28 mutants, and hbl-1(RNAi). alg-1 or alg-1 ain-1 mutant alae resemble ain-1 alae, indicating that ALG-1 and AIN-1 act in a common genetic pathway. AIN-1 is homologous to Brugia malayi 14748.m00068, 14052.m00191, and 14963.m01790, and paralogous to C. elegans B0041.2. AIN-1 and its nematode homologs have weak similarity to human TNRC6A (GW182. OMIM:610739) and Drosophila GAWKY. [Source: WormBase] |
| C06G1.4 | C06G1.4.2 | ain-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | ain-1 encodes an unfamiliar protein synergistically required, with LIN-31, for the normal timing of vulval differentiation, independently of LET-60/RAS, and parallel to or downstream of LIN-14/LIN-28/HBL-1. AIN-1 is expressed in cytoplasmic foci (that are probably P bodies) in several tissues, including vulval precursor cells and neurons. AIN-1 coimmunoprecipitates with DCR-1 and ALG-1, also binds ALG-1 in vitro, and does not require DNA or RNA for its binding. in vivo, AIN-1 targets ALG-1 to cytoplasmic foci, in which it colocalizes with DCAP-2. AIN-1 is likely to be a RISC component, since anti-AIN-1 antibodies precipitate 29 different miRNAs, including mir-2, mir-52, mir-58, mir-71, mir-77, and mir-239a. ain-1(ku322) mutants are essentially wild-type, except for sporadically gapped alae and excess seam cell nuclei arising from retarded seam cell fusion. more prominently, ain-1(ku322) suppresses the multivulva phenotype of lin-31(n1053) mutations, while strongly enhancing lin-31(n1053)'s egg-laying defect. the cellular basis of lin-31(n1053).ain-1(ku322) phenotypes is a delay in vulval development in L4 larvae not seen with either mutation alone. ain-1(ku322) has no effect on let-60(n1046) or lin-3(e1275) mutations. ain-1(ku322) suppresses the precocious vulval development of lin-14(RNAi), lin-28 mutants, and hbl-1(RNAi). alg-1 or alg-1 ain-1 mutant alae resemble ain-1 alae, indicating that ALG-1 and AIN-1 act in a common genetic pathway. AIN-1 is homologous to Brugia malayi 14748.m00068, 14052.m00191, and 14963.m01790, and paralogous to C. elegans B0041.2. AIN-1 and its nematode homologs have weak similarity to human TNRC6A (GW182. OMIM:610739) and Drosophila GAWKY. [Source: WormBase] |
| C09B7.1 | C09B7.1a | ser-7 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | ser-7 encodes an ortholog of mammalian 5-HT7 metabotropic serotonin receptors. SER-7 is required for stimulation of egg-laying or pharyngeal pumping by serotonin (5-HT), for regular pumping in response to bacteria, and probably also for 5-HT to activate MC neurons. SER-7 and SER-1 are redundantly required for normal egg-laying. SER-7 is expressed in head and tail neurons, pharyngeal neurons (M4, MCs, I2s, I3, M5, M3s, I4, I6, and M2s), vulval muscles, and intestine. heterologously expressed SER-7, when challenged with 5-HT, stimulates intracellular adenylate cyclase activity. SER-7 has high affinity for 5-HT and tryptamine, but not for 5-CT, and is unaffected by at least some agonists of mammalian 5-HT7 receptors. [Source: WormBase] |
| C09B7.1 | C09B7.1b | ser-7 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | ser-7 encodes an ortholog of mammalian 5-HT7 metabotropic serotonin receptors. SER-7 is required for stimulation of egg-laying or pharyngeal pumping by serotonin (5-HT), for regular pumping in response to bacteria, and probably also for 5-HT to activate MC neurons. SER-7 and SER-1 are redundantly required for normal egg-laying. SER-7 is expressed in head and tail neurons, pharyngeal neurons (M4, MCs, I2s, I3, M5, M3s, I4, I6, and M2s), vulval muscles, and intestine. heterologously expressed SER-7, when challenged with 5-HT, stimulates intracellular adenylate cyclase activity. SER-7 has high affinity for 5-HT and tryptamine, but not for 5-CT, and is unaffected by at least some agonists of mammalian 5-HT7 receptors. [Source: WormBase] |
| C09B7.1 | C09B7.1c | ser-7 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | ser-7 encodes an ortholog of mammalian 5-HT7 metabotropic serotonin receptors. SER-7 is required for stimulation of egg-laying or pharyngeal pumping by serotonin (5-HT), for regular pumping in response to bacteria, and probably also for 5-HT to activate MC neurons. SER-7 and SER-1 are redundantly required for normal egg-laying. SER-7 is expressed in head and tail neurons, pharyngeal neurons (M4, MCs, I2s, I3, M5, M3s, I4, I6, and M2s), vulval muscles, and intestine. heterologously expressed SER-7, when challenged with 5-HT, stimulates intracellular adenylate cyclase activity. SER-7 has high affinity for 5-HT and tryptamine, but not for 5-CT, and is unaffected by at least some agonists of mammalian 5-HT7 receptors. [Source: WormBase] |
| C09B8.4 | C09B8.4 | C09B8.4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C09B8.7 | C09B8.7a.1 | pak-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | pak-1 encodes, by alternative splicing, at least five isoforms of a putative p21-activated kinase orthologous to human PAK1, PAK2 (OMIM:?), and PAK3 (OMIM:300142, mutated in nonsyndromic mental retardation). PAK-1 is required (redundantly with its paralog, MAX-2) for normal axonal guidance of motoneurons, P cell migration, and locomotion, with max-2(cy2).pak-1(ok448) double mutants phenotypically resembling unc-73 or ced-10.mig-2 mutants. pak-1 is expressed in pharyngeal muscles, CAN neurons, ventral cord motoneurons, migrating distal tip cells, developing uterus, B, Y, and T cells in the male tail, and vulval muscle cells. by itself, the null pak-1(ok448) mutation has no known phenotype. [Source: WormBase] |
| C09B8.7 | C09B8.7a.2 | pak-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | pak-1 encodes, by alternative splicing, at least five isoforms of a putative p21-activated kinase orthologous to human PAK1, PAK2 (OMIM:?), and PAK3 (OMIM:300142, mutated in nonsyndromic mental retardation). PAK-1 is required (redundantly with its paralog, MAX-2) for normal axonal guidance of motoneurons, P cell migration, and locomotion, with max-2(cy2).pak-1(ok448) double mutants phenotypically resembling unc-73 or ced-10.mig-2 mutants. pak-1 is expressed in pharyngeal muscles, CAN neurons, ventral cord motoneurons, migrating distal tip cells, developing uterus, B, Y, and T cells in the male tail, and vulval muscle cells. by itself, the null pak-1(ok448) mutation has no known phenotype. [Source: WormBase] |
| C09G1.2 | C09G1.2 | C09G1.2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C09G1.4 | C09G1.4 | C09G1.4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C10A4.3 | C10A4.3 | C10A4.3 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C10A4.5 | C10A4.5 | C10A4.5 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C10E2.3 | C10E2.3 | hda-4 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | hda-4 encodes a class II histone deacetylase that contains a putative MEF-2 DNA binding domain, a nuclear localization signal domain, and a single catalytic domain and may affect locomotion, body morphology, and growth. interacts with MEF-2 in in vitro assays and is expressed in body-wall muscle, neurons, and hypodermal seam cells [Source: WormBase] |
| C11G6.2 | C11G6.2 | C11G6.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C11G6.4 | C11G6.4a | nhr-28 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C11H1.2 | C11H1.2 | C11H1.2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C14A11.7 | C14A11.7 | ssr-2 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C14F11.2 | C14F11.2 | C14F11.2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C14H10.3 | C14H10.3a | C14H10.3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C14H10.3 | C14H10.3b.1 | C14H10.3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C14H10.3 | C14H10.3b.2 | C14H10.3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C14H10.4 | C14H10.4 | str-74 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C15B12.2 | C15B12.2.1 | C15B12.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C15B12.2 | C15B12.2.2 | C15B12.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C15B12.4 | C15B12.4 | C15B12.4 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C16B8.1 | C16B8.1.1 | lin-18 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | lin-18 encodes a predicted receptor tyrosine kinase that is a member of the Ryk/Derailed family of tyrosine kinase-related receptors (OMIM:600524, mutations in humans are associated with cleft palate). in C. elegans, LIN-18 is required for establishing the polarity of the secondary vulval cell lineage produced by the P7.p vulval precursor cell. LIN-18 may be a receptor for Wnt-like signaling molecules, and in vulval development appears to function independently of, but in parallel with, LIN-17, a Frizzled-like Wnt receptor, also required for proper orientation of the P7.p lineage. a lin-18 reporter gene is expressed in body wall muscle, neurons, and the developing vulva. in the vulva, expression is detected in P5.p, P6.p, and P7.p and all of their descendants during the L3 and L4 larval stages. [Source: WormBase] |
| C16B8.1 | C16B8.1.2 | lin-18 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | lin-18 encodes a predicted receptor tyrosine kinase that is a member of the Ryk/Derailed family of tyrosine kinase-related receptors (OMIM:600524, mutations in humans are associated with cleft palate). in C. elegans, LIN-18 is required for establishing the polarity of the secondary vulval cell lineage produced by the P7.p vulval precursor cell. LIN-18 may be a receptor for Wnt-like signaling molecules, and in vulval development appears to function independently of, but in parallel with, LIN-17, a Frizzled-like Wnt receptor, also required for proper orientation of the P7.p lineage. a lin-18 reporter gene is expressed in body wall muscle, neurons, and the developing vulva. in the vulva, expression is detected in P5.p, P6.p, and P7.p and all of their descendants during the L3 and L4 larval stages. [Source: WormBase] |
| C17G1.4 | C17G1.4a | nra-3 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C17G1.4 | C17G1.4b | nra-3 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C17G1.7 | C17G1.7.1 | C17G1.7 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C17H11.6 | C17H11.6a | C17H11.6 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C17H11.6 | C17H11.6b | C17H11.6 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C17H11.6 | C17H11.6c.1 | C17H11.6 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C17H11.6 | C17H11.6c.2 | C17H11.6 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C17H11.6 | C17H11.6c.3 | C17H11.6 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C17H11.6 | C17H11.6d | C17H11.6 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C18B12.2 | C18B12.2 | C18B12.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | C18B12.2 encodes a G-protein-coupled receptor (GPCR) that is a member of the secretin family (also known as family B or family 2) of GPCRs. [Source: WormBase] |
| C18B2.6 | C18B2.6 | C18B2.6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C23F12.1 | C23F12.1a | fln-2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C23F12.1 | C23F12.1c | fln-2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C23F12.1 | C23F12.1d | fln-2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C23H4.2 | C23H4.2 | C23H4.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C23H4.6 | C23H4.6a | C23H4.6 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C23H4.6 | C23H4.6b | C23H4.6 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C23H4.8 | C23H4.8 | C23H4.8 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C24A8.3 | C24A8.3 | pqn-15 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77). [Source: WormBase] |
| C25B8.3 | C25B8.3a | cpr-6 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C25B8.3 | C25B8.3b | cpr-6 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C25B8.3 | C25B8.3c | cpr-6 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C25G6.2 | C25G6.2 | tsp-9 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C25G6.5 | C25G6.5 | npr-11 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C28G1.4 | C28G1.4 | C28G1.4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C29F7.1 | C29F7.1 | C29F7.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C29F7.2 | C29F7.2 | C29F7.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C29F7.5 | C29F7.5 | fkh-4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | fkh-4 encodes a member of the forkhead domain transcription factor family. [Source: WormBase] |
| C29F7.6 | C29F7.6 | C29F7.6 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | C29F7.6 encodes a putative histone H3 di/trimethyllysine-27 (H3K27me2/me3) demethylase. C29F7.6 contains a C-terminal JmjC domain, and is homologous to human JMJD3, UTX (OMIM:300128), and UTY (OMIM:400009). C29F7.6 is expected to antagonize transcriptional repression by polycomb repressor complexes, which mark stem cells (and presumably germline) by H3K27me3-mediated repression of somatic genes. however, C29F7.6 has no obvious function in mass RNAi assays. [Source: WormBase] |
| C31E10.8 | C31E10.8 | tbc-19 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C31H2.2 | C31H2.2 | dpy-8 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | dpy-8 encodes a collagen with a nematode-specific N-terminal domain that is required for normal body morphology and (perhaps) for a normal embryonic cell division rate. dpy-8 interacts genetically with emb-5 and glp-1. [Source: WormBase] |
| C33A11.1 | C33A11.1.1 | C33A11.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C33A11.1 | C33A11.1.2 | C33A11.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C33A11.1 | C33A11.1.3 | C33A11.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C33D12.6 | C33D12.6 | tag-312 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C33E10.8 | C33E10.8 | C33E10.8 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins. [Source: WormBase] |