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Genome: Caenorhabditis Elegans | mRNA | miRBase 18 (Nov. 2011), ENSEMBL 65 (Dec. 2011) and RNA22v1.0
Description: List of transcripts that are targeted by all of the below miRNA identifiers simultaneously
miRNA's: cel-miR-62 (MIMAT0000034)
Filtering By: Base pair min value: 12 | Folding energy max value (Kcal/mol): -21 | Min miRNA targets: 1


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Gene IDTranscript IDCommon Gene Name# of miRNA targets
for specified miRNAs
ChromosomeStrand DirectionTranscript Link to view miRNA target predictionsGene LinkDescription
AH9.1AH9.1AH9.1123 XReverseView as cDNA map |
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Ensembl
AH9.4AH9.4AH9.4123 XReverseView as cDNA map |
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Ensembl
B0198.1B0198.1tsp-20123 XReverseView as cDNA map |
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Ensembl
B0198.3B0198.3aB0198.3223 XReverseView as cDNA map |
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Ensembl
B0302.1B0302.1a.1kin-25123 XForwardView as cDNA map |
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Ensembl
kin-25 encodes a nonreceptor tyrosine kinase that is a member of the Ack subfamily of cytoplasmic tyrosine kinases. [Source: WormBase]
B0302.1B0302.1a.2kin-25123 XForwardView as cDNA map |
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Ensembl
kin-25 encodes a nonreceptor tyrosine kinase that is a member of the Ack subfamily of cytoplasmic tyrosine kinases. [Source: WormBase]
B0302.1B0302.1bkin-25123 XForwardView as cDNA map |
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Ensembl
kin-25 encodes a nonreceptor tyrosine kinase that is a member of the Ack subfamily of cytoplasmic tyrosine kinases. [Source: WormBase]
B0302.2B0302.2B0302.2123 XForwardView as cDNA map |
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Ensembl
B0310.2B0310.2.1B0310.2123 XReverseView as cDNA map |
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Ensembl
B0310.2B0310.2.2B0310.2123 XReverseView as cDNA map |
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Ensembl
B0395.1B0395.1nhx-1123 XForwardView as cDNA map |
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Ensembl
nhx-1 encodes a sodium/proton exchanger expressed intracellularly within hypodermal and muscle cells. NHX-1 is required for embryonic viability, and is thought to prevent intracellular acidification by catalysing the electroneutral exchange of vesicular sodium for an intracellular proton. [Source: WormBase]
B0403.2B0403.2ubc-17123 XForwardView as cDNA map |
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Ensembl
B0403.3B0403.3B0403.3223 XReverseView as cDNA map |
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Ensembl
B0410.1B0410.1B0410.1123 XForwardView as cDNA map |
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Ensembl
B0416.3B0416.3B0416.3123 XForwardView as cDNA map |
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Ensembl
B0416.5B0416.5aB0416.5123 XReverseView as cDNA map |
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Ensembl
B0563.6B0563.6aB0563.6123 XForwardView as cDNA map |
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Ensembl
B0563.6B0563.6b.1B0563.6123 XForwardView as cDNA map |
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Ensembl
B0563.6B0563.6b.2B0563.6123 XForwardView as cDNA map |
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Ensembl
B0563.6B0563.6cB0563.6123 XForwardView as cDNA map |
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Ensembl
B0563.7B0563.7B0563.7123 XReverseView as cDNA map |
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Ensembl
C01C10.1C01C10.1clc-2123 XForwardView as cDNA map |
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Ensembl
clc-2 encodes a claudin homolog, closely similar to CLC-1, that is required for normal cohesion of apical junctions in epithelia. claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water. CLC-2 maintains the impermeability ('barrier function') of epithelia, since clc-1(RNAi) animals have abnormal permeability of the hypodermis to dyes. clc-2 is expressed in hypodermal seam cells, with two diffuse lines of CLC-2 protein. [Source: WormBase]
C01C10.3C01C10.3.1acl-12123 XReverseView as cDNA map |
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Ensembl
C01C10.3C01C10.3.2acl-12123 XReverseView as cDNA map |
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Ensembl
C01C4.2C01C4.2C01C4.2123 XForwardView as cDNA map |
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Ensembl
C02B4.1C02B4.1adt-1223 XForwardView as cDNA map |
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Ensembl
The adt-1 gene encodes a metalloproteinase with disintegrin-like and metalloproteinase with thrombospondin type I motifs (ADAMTS) that is required for male tail morphogenesis. [Source: WormBase]
C02B4.2C02B4.2nhr-17123 XReverseView as cDNA map |
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Ensembl
nhr-17 encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators. nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain. [Source: WormBase]
C02B4.3C02B4.3C02B4.3123 XReverseView as cDNA map |
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Ensembl
C02B8.1C02B8.1.1C02B8.1123 XForwardView as cDNA map |
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Ensembl
C02B8.1C02B8.1.2C02B8.1123 XForwardView as cDNA map |
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Ensembl
C02B8.3C02B8.3C02B8.3123 XForwardView as cDNA map |
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Ensembl
C02B8.4C02B8.4hlh-8123 XForwardView as cDNA map |
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Ensembl
The hlh-8 gene encodes a helix-loop-helix protein required for normal muscle development, and hence for normal defecation and egg-laying. [Source: WormBase]
C02B8.5C02B8.5C02B8.5223 XReverseView as cDNA map |
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Ensembl
C02B8.5 encodes a homolog of the functionally active Fmrf Receptor (FR. CG2114) of D. melanogaster. it is thus possible that C02B8.5 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12). [Source: WormBase]
C02C6.1C02C6.1adyn-1223 XForwardView as cDNA map |
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Ensembl
dyn-1 encodes the C. elegans ortholog of the dynamin GTPase. dyn-1 activity is required for endocytosis, synaptic vesicle recycling, cytokinesis, and the CED-1 pathway that regulates engulfment and degradation of apoptotic cells. mutations in dyn-1 affect locomotion, egg-laying, defecation, and embryonic development, indicating that dyn-1's endocytic function is required for a number of diverse processes. dyn-1 reporter fusion constructs are expressed in motor neurons, intestinal cells, and pharyngeal muscle. [Source: WormBase]
C02C6.1C02C6.1bdyn-1223 XForwardView as cDNA map |
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Ensembl
dyn-1 encodes the C. elegans ortholog of the dynamin GTPase. dyn-1 activity is required for endocytosis, synaptic vesicle recycling, cytokinesis, and the CED-1 pathway that regulates engulfment and degradation of apoptotic cells. mutations in dyn-1 affect locomotion, egg-laying, defecation, and embryonic development, indicating that dyn-1's endocytic function is required for a number of diverse processes. dyn-1 reporter fusion constructs are expressed in motor neurons, intestinal cells, and pharyngeal muscle. [Source: WormBase]
C02C6.2C02C6.2aolrn-1123 XForwardView as cDNA map |
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Ensembl
olrn-1 encodes, by alternative splicing, two isoforms of a transmembrane protein required for differentiation of the AWC[ON] neuron, expression of str-2 in AWC[ON], adaptation to benzaldehyde, chemotaxis to butanone, and enhancement of chemotaxis to butanone by the presence of food. OLRN-1 is orthologous to Drosophila melanogaster RAW and Schistosoma japonicum SJCHGC05616. while OLRN-1 has orthologs in nematodes, trematodes, and arthropods, its has no obvious chordate homologs. OLRN-6 is expressed in many pharyngeal neurons and some head neurons, but is required solely in the AWC[ON] neuron for butanone enhancement. OLRN-6's function in butanone enhancement is both serotonin- and dopamine-independent, and appears to also act in chemotactic enhancement of 2,3-pentanedione and isoamyl alcohol. by orthology with RAW, OLRN-6 is predicted to inhibit JNK-1 signalling, which may in turn allow the asymmetrical AWC[ON] fate to emerge. [Source: WormBase]
C02D4.2C02D4.2aser-2223 XReverseView as cDNA map |
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Ensembl
ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase]
C02D4.2C02D4.2bser-2223 XReverseView as cDNA map |
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Ensembl
ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase]
C02D4.2C02D4.2eser-2223 XReverseView as cDNA map |
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Ensembl
ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase]
C02D4.2C02D4.2fser-2223 XReverseView as cDNA map |
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Ensembl
ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase]
C02F12.1C02F12.1btsp-17123 XForwardView as cDNA map |
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Ensembl
C02F12.7C02F12.7tag-278123 XReverseView as cDNA map |
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Ensembl
C02F12.9C02F12.9C02F12.9123 XForwardView as cDNA map |
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Ensembl
C02H7.2C02H7.2npr-19323 XReverseView as cDNA map |
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Ensembl
C02H7.3C02H7.3aaex-3423 XReverseView as cDNA map |
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Ensembl
aex-3 encodes a guanine nucleotide exchange factor for the rab-3 GTPase that is orthologous to human MAP kinase activating protein containing death domain (MADD, OMIM:603584). AEX-3 is required for intracellular vesicle trafficking as well as synaptic vesicle release and interacts with CAB-1 and RAB-3 to regulate separate pathways for neural activities such as defecation and male mating, respectively. AEX-3 is also required for egg laying and locomotion. AEX-3 is expressed in nearly all neurons. [Source: WormBase]
C03A3.1C03A3.1aC03A3.1123 XForwardView as cDNA map |
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Ensembl
C03A3.1C03A3.1bC03A3.1123 XForwardView as cDNA map |
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Ensembl
C03A3.2C03A3.2.1C03A3.2123 XForwardView as cDNA map |
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Ensembl
C03A3.2C03A3.2.2C03A3.2123 XForwardView as cDNA map |
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Ensembl
C03A3.3C03A3.3C03A3.3123 XReverseView as cDNA map |
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Ensembl
C03B1.1C03B1.1C03B1.1123 XForwardView as cDNA map |
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Ensembl
C03B1.4C03B1.4C03B1.4123 XForwardView as cDNA map |
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Ensembl
C03B1.5C03B1.5C03B1.5123 XForwardView as cDNA map |
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Ensembl
C03B1.7C03B1.7C03B1.7123 XForwardView as cDNA map |
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Ensembl
C03F11.3C03F11.3scav-1123 XReverseView as cDNA map |
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Ensembl
C04A11.3C04A11.3gck-4323 XForwardView as cDNA map |
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Ensembl
C04A11.5C04A11.5.1C04A11.5123 XForwardView as cDNA map |
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Ensembl
C04A11.5C04A11.5.2C04A11.5123 XForwardView as cDNA map |
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Ensembl
C04B4.5C04B4.5C04B4.5123 XReverseView as cDNA map |
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Ensembl
C04B4.5 encodes a novel protein. [Source: WormBase]
C04F6.4C04F6.4aunc-78223 XReverseView as cDNA map |
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Ensembl
The unc-78 gene encodes a homolog of actin-interacting protein 1 (AIP1) that regulates the ordered assembly of actin and cofilin in myofibrils. [Source: WormBase]
C04F6.7C04F6.7C04F6.7123 XReverseView as cDNA map |
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Ensembl
C05A9.1C05A9.1apgp-5123 XReverseView as cDNA map |
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Ensembl
pgp-5 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily. by homology, PGP-5 is predicted to function as an ATP-dependent efflux pump that protects C. elegans by exporting exogenous toxins. however, as loss of pgp-5 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of PGP-5 in C. elegans development and/or behavior is not yet known. [Source: WormBase]
C05A9.1C05A9.1bpgp-5123 XReverseView as cDNA map |
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Ensembl
pgp-5 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily. by homology, PGP-5 is predicted to function as an ATP-dependent efflux pump that protects C. elegans by exporting exogenous toxins. however, as loss of pgp-5 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of PGP-5 in C. elegans development and/or behavior is not yet known. [Source: WormBase]
C05A9.2C05A9.2C05A9.2123 XReverseView as cDNA map |
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Ensembl
C05C9.1C05C9.1C05C9.1223 XForwardView as cDNA map |
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Ensembl
C05C9.3C05C9.3C05C9.3423 XReverseView as cDNA map |
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Ensembl
The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77). [Source: WormBase]
C05D9.5C05D9.5ife-4123 XForwardView as cDNA map |
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Ensembl
The ife-4 gene encodes a member of the Initiation Factor 4E (eIF4E) family. [Source: WormBase]
C05E11.2C05E11.2C05E11.2123 XForwardView as cDNA map |
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Ensembl
C05E11.4C05E11.4amt-1223 XForwardView as cDNA map |
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Ensembl
amt-1 encodes a transmembrane transporter that by homology, is predicted to transport ammonium ions across the plasma membrane. as loss of amt-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of AMT-1 in C. elegans development and/or behavior is not yet known. [Source: WormBase]
C05E11.5C05E11.5amt-4123 XForwardView as cDNA map |
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amt-4 encodes a member of the ammonium transporter protein family. [Source: WormBase]
C05E11.7C05E11.7C05E11.7223 XReverseView as cDNA map |
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Ensembl
C05E7.1C05E7.1C05E7.1123 XReverseView as cDNA map |
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Ensembl
C05E7.4C05E7.4C05E7.4223 XForwardView as cDNA map |
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Ensembl
C05G5.2C05G5.2C05G5.2123 XForwardView as cDNA map |
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Ensembl
C05G5.3C05G5.3C05G5.3123 XReverseView as cDNA map |
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Ensembl
C06E2.2C06E2.2C06E2.2123 XForwardView as cDNA map |
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Ensembl
C06G1.6C06G1.6C06G1.6123 XReverseView as cDNA map |
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Ensembl
C07A4.2C07A4.2C07A4.2123 XForwardView as cDNA map |
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Ensembl
C07A4.3C07A4.3C07A4.3123 XForwardView as cDNA map |
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Ensembl
C07B5.4C07B5.4a.1C07B5.4223 XForwardView as cDNA map |
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Ensembl
C07B5.4C07B5.4a.2C07B5.4223 XForwardView as cDNA map |
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Ensembl
C08A9.3C08A9.3aC08A9.3123 XReverseView as cDNA map |
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Ensembl
C08A9.3C08A9.3bC08A9.3123 XReverseView as cDNA map |
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Ensembl
C08A9.9C08A9.9.1C08A9.9123 XReverseView as cDNA map |
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Ensembl
C08A9.9C08A9.9.2C08A9.9123 XReverseView as cDNA map |
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Ensembl
C09B7.1C09B7.1aser-7123 XForwardView as cDNA map |
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ser-7 encodes an ortholog of mammalian 5-HT7 metabotropic serotonin receptors. SER-7 is required for stimulation of egg-laying or pharyngeal pumping by serotonin (5-HT), for regular pumping in response to bacteria, and probably also for 5-HT to activate MC neurons. SER-7 and SER-1 are redundantly required for normal egg-laying. SER-7 is expressed in head and tail neurons, pharyngeal neurons (M4, MCs, I2s, I3, M5, M3s, I4, I6, and M2s), vulval muscles, and intestine. heterologously expressed SER-7, when challenged with 5-HT, stimulates intracellular adenylate cyclase activity. SER-7 has high affinity for 5-HT and tryptamine, but not for 5-CT, and is unaffected by at least some agonists of mammalian 5-HT7 receptors. [Source: WormBase]
C09B7.1C09B7.1bser-7123 XForwardView as cDNA map |
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Ensembl
ser-7 encodes an ortholog of mammalian 5-HT7 metabotropic serotonin receptors. SER-7 is required for stimulation of egg-laying or pharyngeal pumping by serotonin (5-HT), for regular pumping in response to bacteria, and probably also for 5-HT to activate MC neurons. SER-7 and SER-1 are redundantly required for normal egg-laying. SER-7 is expressed in head and tail neurons, pharyngeal neurons (M4, MCs, I2s, I3, M5, M3s, I4, I6, and M2s), vulval muscles, and intestine. heterologously expressed SER-7, when challenged with 5-HT, stimulates intracellular adenylate cyclase activity. SER-7 has high affinity for 5-HT and tryptamine, but not for 5-CT, and is unaffected by at least some agonists of mammalian 5-HT7 receptors. [Source: WormBase]
C09B7.1C09B7.1cser-7123 XForwardView as cDNA map |
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ser-7 encodes an ortholog of mammalian 5-HT7 metabotropic serotonin receptors. SER-7 is required for stimulation of egg-laying or pharyngeal pumping by serotonin (5-HT), for regular pumping in response to bacteria, and probably also for 5-HT to activate MC neurons. SER-7 and SER-1 are redundantly required for normal egg-laying. SER-7 is expressed in head and tail neurons, pharyngeal neurons (M4, MCs, I2s, I3, M5, M3s, I4, I6, and M2s), vulval muscles, and intestine. heterologously expressed SER-7, when challenged with 5-HT, stimulates intracellular adenylate cyclase activity. SER-7 has high affinity for 5-HT and tryptamine, but not for 5-CT, and is unaffected by at least some agonists of mammalian 5-HT7 receptors. [Source: WormBase]
C09B8.8C09B8.8C09B8.8123 XForwardView as cDNA map |
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Ensembl
C09C7.1C09C7.1zig-4123 XForwardView as cDNA map |
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zig-4 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins. ZIG-4 activity is required for maintenance of ventral nerve cord organization: the AVKL/R and PVQL/R axons of the left and right ventral nerve cords do not maintain their proper spatial positions and drift into the opposite cord. a zig-4::gfp reporter fusion is expressed in the PVT, ASK, BAG, and M2 neurons, with expression also seen during the L1 stage in pharyngeal mesoderm and ectoderm. [Source: WormBase]
C09F12.1C09F12.1.1clc-1223 XForwardView as cDNA map |
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clc-1 encodes a claudin homolog, closely similar to CLC-2, that is required for normal cohesion of apical junctions in epithelia. claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water. CLC-1 maintains the impermeability ('barrier function') of epithelia, since clc-1(RNAi) animals have abnormal permeability of the pharynx to dyes. clc-1 is expressed in spermatheca, pharynx, intestine, hypodermis, the excretory-secretory system, and the cell-cell junctions of the vulva. in pharyngeal cells, CLC-1 colocalizes with AJM-1 in long thin lines, parallel to the pharyngeal axis and lining the lumenal surface, that appear to correspond with apical intercellular junctions. [Source: WormBase]
C09F12.1C09F12.1.2clc-1223 XForwardView as cDNA map |
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Ensembl
clc-1 encodes a claudin homolog, closely similar to CLC-2, that is required for normal cohesion of apical junctions in epithelia. claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water. CLC-1 maintains the impermeability ('barrier function') of epithelia, since clc-1(RNAi) animals have abnormal permeability of the pharynx to dyes. clc-1 is expressed in spermatheca, pharynx, intestine, hypodermis, the excretory-secretory system, and the cell-cell junctions of the vulva. in pharyngeal cells, CLC-1 colocalizes with AJM-1 in long thin lines, parallel to the pharyngeal axis and lining the lumenal surface, that appear to correspond with apical intercellular junctions. [Source: WormBase]
C09G1.4C09G1.4C09G1.4123 XReverseView as cDNA map |
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Ensembl
C10A4.1C10A4.1C10A4.1123 XForwardView as cDNA map |
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Ensembl
C10A4.4C10A4.4C10A4.4123 XForwardView as cDNA map |
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Ensembl
C10A4.8C10A4.8mnm-2123 XReverseView as cDNA map |
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Ensembl
C10E2.1C10E2.1C10E2.1123 XForwardView as cDNA map |
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Ensembl
C10E2.2C10E2.2.1C10E2.2223 XForwardView as cDNA map |
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This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins. [Source: WormBase]
C10E2.6C10E2.6.1C10E2.6223 XReverseView as cDNA map |
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Ensembl
C10E2.6C10E2.6.2C10E2.6223 XReverseView as cDNA map |
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Ensembl
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We gratefully acknowledge support of this work by the William M. Keck Foundation