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Genome: Caenorhabditis Elegans | mRNA | miRBase 18 (Nov. 2011), ENSEMBL 65 (Dec. 2011) and RNA22v1.0
Description: List of transcripts that are targeted by all of the below miRNA identifiers simultaneously
miRNA's: cel-miR-77-3p (MIMAT0000049)
Filtering By: Base pair min value: 12 | Folding energy max value (Kcal/mol): -21 | Min miRNA targets: 1


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Gene IDTranscript IDCommon Gene Name# of miRNA targets
for specified miRNAs
ChromosomeStrand DirectionTranscript Link to view miRNA target predictionsGene LinkDescription
AC8.10AC8.10AC8.10223 XReverseView as cDNA map |
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Ensembl
AC8.3AC8.3AC8.3223 XReverseView as cDNA map |
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Ensembl
AH9.2AH9.2crn-4123 XReverseView as cDNA map |
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Ensembl
AH9.6AH9.6AH9.6323 XReverseView as cDNA map |
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Ensembl
AH9.6 encodes a novel protein that contains two predicted transmembrane domains and that is conserved in other nematode species. [Source: WormBase]
B0198.3B0198.3aB0198.3523 XReverseView as cDNA map |
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Ensembl
B0272.1B0272.1tbb-4123 XReverseView as cDNA map |
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Ensembl
B0272.4B0272.4B0272.4423 XForwardView as cDNA map |
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Ensembl
B0302.1B0302.1a.1kin-25523 XForwardView as cDNA map |
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Ensembl
kin-25 encodes a nonreceptor tyrosine kinase that is a member of the Ack subfamily of cytoplasmic tyrosine kinases. [Source: WormBase]
B0302.1B0302.1a.2kin-25523 XForwardView as cDNA map |
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Ensembl
kin-25 encodes a nonreceptor tyrosine kinase that is a member of the Ack subfamily of cytoplasmic tyrosine kinases. [Source: WormBase]
B0302.1B0302.1bkin-25523 XForwardView as cDNA map |
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Ensembl
kin-25 encodes a nonreceptor tyrosine kinase that is a member of the Ack subfamily of cytoplasmic tyrosine kinases. [Source: WormBase]
B0310.2B0310.2.1B0310.2223 XReverseView as cDNA map |
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Ensembl
B0310.2B0310.2.2B0310.2223 XReverseView as cDNA map |
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Ensembl
B0310.3B0310.3B0310.3123 XReverseView as cDNA map |
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Ensembl
B0310.5B0310.5ugt-46223 XReverseView as cDNA map |
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Ensembl
B0310.6B0310.6B0310.6123 XReverseView as cDNA map |
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Ensembl
B0344.2B0344.2wrt-9323 XForwardView as cDNA map |
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Ensembl
wrt-9 encodes a hedgehog-like protein, with an N-terminal signal sequence, a Wart domain, and a C-terminal region of proline-rich, low-complexity sequence. the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins. WRT-9 has no obvious function in RNAi assays. [Source: WormBase]
B0395.1B0395.1nhx-1223 XForwardView as cDNA map |
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Ensembl
nhx-1 encodes a sodium/proton exchanger expressed intracellularly within hypodermal and muscle cells. NHX-1 is required for embryonic viability, and is thought to prevent intracellular acidification by catalysing the electroneutral exchange of vesicular sodium for an intracellular proton. [Source: WormBase]
B0395.2B0395.2mboa-1123 XForwardView as cDNA map |
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mboa-1 encodes a putative acyl-Coenzyme A:cholesterol ('sterol') O-acyltransferase, orthologous to human SOAT1 (OMIM:102642). MBOA-1 is required for normal locomotion and normally long lifespan in mass RNAi assays. mboa-1 is expressed in the seam cells and nervous systems of larvae and adults, and in the adult reproductive system. [Source: WormBase]
B0395.3B0395.3.1B0395.3223 XReverseView as cDNA map |
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Ensembl
B0395.3 is orthologous to the human gene CHOLINE ACETYLTRANSFERASE ISOFORM R (CHAT. OMIM:118490), which when mutated leads to disease. [Source: WormBase]
B0395.3B0395.3.2B0395.3223 XReverseView as cDNA map |
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Ensembl
B0395.3 is orthologous to the human gene CHOLINE ACETYLTRANSFERASE ISOFORM R (CHAT. OMIM:118490), which when mutated leads to disease. [Source: WormBase]
B0403.2B0403.2ubc-17323 XForwardView as cDNA map |
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B0403.4B0403.4tag-320423 XReverseView as cDNA map |
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B0403.5B0403.5B0403.5123 XForwardView as cDNA map |
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B0403.6B0403.6B0403.6123 XReverseView as cDNA map |
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B0410.2B0410.2avang-1123 XForwardView as cDNA map |
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vang-1 encodes an ortholog of Drosophila VAN GOGH (also known as STRABISMUS). VANG-1 enables Wnt-directed planar cell polarity. VANG-1 is required for the fully asymmetrical division of B.a versus B.p cells, though this requirement is quantitatively weak. [Source: WormBase]
B0410.2B0410.2bvang-1123 XForwardView as cDNA map |
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Ensembl
vang-1 encodes an ortholog of Drosophila VAN GOGH (also known as STRABISMUS). VANG-1 enables Wnt-directed planar cell polarity. VANG-1 is required for the fully asymmetrical division of B.a versus B.p cells, though this requirement is quantitatively weak. [Source: WormBase]
B0410.3B0410.3B0410.3123 XReverseView as cDNA map |
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B0416.1B0416.1B0416.1223 XForwardView as cDNA map |
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B0416.7B0416.7aB0416.7123 XReverseView as cDNA map |
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B0416.7B0416.7bB0416.7123 XReverseView as cDNA map |
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B0563.10B0563.10B0563.10123 XReverseView as cDNA map |
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B0563.2B0563.2tsp-11123 XForwardView as cDNA map |
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B0563.4B0563.4.1tmbi-4123 XForwardView as cDNA map |
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B0563.4B0563.4.2tmbi-4123 XForwardView as cDNA map |
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B0563.6B0563.6aB0563.6123 XForwardView as cDNA map |
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B0563.6B0563.6b.1B0563.6123 XForwardView as cDNA map |
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B0563.6B0563.6b.2B0563.6123 XForwardView as cDNA map |
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B0563.7B0563.7B0563.7123 XReverseView as cDNA map |
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C01C10.2C01C10.2aC01C10.2123 XReverseView as cDNA map |
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C01C10.2C01C10.2bC01C10.2123 XReverseView as cDNA map |
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C01C10.3C01C10.3.1acl-12123 XReverseView as cDNA map |
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C01C10.3C01C10.3.2acl-12123 XReverseView as cDNA map |
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C01C10.4C01C10.4clc-5223 XForwardView as cDNA map |
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clc-5 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia. CLC-5 is worm-specific, with obvious homologs only in C. elegans. CLC-5 has no obvious function in mass RNAi assays. claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water. [Source: WormBase]
C01C4.1C01C4.1nlp-1123 XForwardView as cDNA map |
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nlp-1 encodes a predicted neuropeptide-like protein of the MSFamide family with similarity to Aplysia californica (sea hare) buccalin, a neuropeptide that regulates acetylcholine-induced muscle contraction. NLP-1 is expressed in the phasmid PHB tail sensory neuron, lateral neurons, head neurons, and the intestine. the precise role of NLP-1 in nervous system function and development is not yet known. [Source: WormBase]
C01C4.2C01C4.2C01C4.2123 XForwardView as cDNA map |
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Ensembl
C02B4.1C02B4.1adt-1323 XForwardView as cDNA map |
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Ensembl
The adt-1 gene encodes a metalloproteinase with disintegrin-like and metalloproteinase with thrombospondin type I motifs (ADAMTS) that is required for male tail morphogenesis. [Source: WormBase]
C02B4.2C02B4.2nhr-17223 XReverseView as cDNA map |
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Ensembl
nhr-17 encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators. nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain. [Source: WormBase]
C02B4.4C02B4.4C02B4.4123 XReverseView as cDNA map |
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Ensembl
C02B8.1C02B8.1.1C02B8.1123 XForwardView as cDNA map |
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C02B8.2C02B8.2fbxc-38123 XForwardView as cDNA map |
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C02B8.5C02B8.5C02B8.5223 XReverseView as cDNA map |
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C02B8.5 encodes a homolog of the functionally active Fmrf Receptor (FR. CG2114) of D. melanogaster. it is thus possible that C02B8.5 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12). [Source: WormBase]
C02B8.6C02B8.6C02B8.6123 XReverseView as cDNA map |
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Ensembl
C02C6.1C02C6.1adyn-1423 XForwardView as cDNA map |
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Ensembl
dyn-1 encodes the C. elegans ortholog of the dynamin GTPase. dyn-1 activity is required for endocytosis, synaptic vesicle recycling, cytokinesis, and the CED-1 pathway that regulates engulfment and degradation of apoptotic cells. mutations in dyn-1 affect locomotion, egg-laying, defecation, and embryonic development, indicating that dyn-1's endocytic function is required for a number of diverse processes. dyn-1 reporter fusion constructs are expressed in motor neurons, intestinal cells, and pharyngeal muscle. [Source: WormBase]
C02C6.1C02C6.1bdyn-1423 XForwardView as cDNA map |
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Ensembl
dyn-1 encodes the C. elegans ortholog of the dynamin GTPase. dyn-1 activity is required for endocytosis, synaptic vesicle recycling, cytokinesis, and the CED-1 pathway that regulates engulfment and degradation of apoptotic cells. mutations in dyn-1 affect locomotion, egg-laying, defecation, and embryonic development, indicating that dyn-1's endocytic function is required for a number of diverse processes. dyn-1 reporter fusion constructs are expressed in motor neurons, intestinal cells, and pharyngeal muscle. [Source: WormBase]
C02C6.2C02C6.2aolrn-1323 XForwardView as cDNA map |
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olrn-1 encodes, by alternative splicing, two isoforms of a transmembrane protein required for differentiation of the AWC[ON] neuron, expression of str-2 in AWC[ON], adaptation to benzaldehyde, chemotaxis to butanone, and enhancement of chemotaxis to butanone by the presence of food. OLRN-1 is orthologous to Drosophila melanogaster RAW and Schistosoma japonicum SJCHGC05616. while OLRN-1 has orthologs in nematodes, trematodes, and arthropods, its has no obvious chordate homologs. OLRN-6 is expressed in many pharyngeal neurons and some head neurons, but is required solely in the AWC[ON] neuron for butanone enhancement. OLRN-6's function in butanone enhancement is both serotonin- and dopamine-independent, and appears to also act in chemotactic enhancement of 2,3-pentanedione and isoamyl alcohol. by orthology with RAW, OLRN-6 is predicted to inhibit JNK-1 signalling, which may in turn allow the asymmetrical AWC[ON] fate to emerge. [Source: WormBase]
C02C6.2C02C6.2bolrn-1323 XForwardView as cDNA map |
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olrn-1 encodes, by alternative splicing, two isoforms of a transmembrane protein required for differentiation of the AWC[ON] neuron, expression of str-2 in AWC[ON], adaptation to benzaldehyde, chemotaxis to butanone, and enhancement of chemotaxis to butanone by the presence of food. OLRN-1 is orthologous to Drosophila melanogaster RAW and Schistosoma japonicum SJCHGC05616. while OLRN-1 has orthologs in nematodes, trematodes, and arthropods, its has no obvious chordate homologs. OLRN-6 is expressed in many pharyngeal neurons and some head neurons, but is required solely in the AWC[ON] neuron for butanone enhancement. OLRN-6's function in butanone enhancement is both serotonin- and dopamine-independent, and appears to also act in chemotactic enhancement of 2,3-pentanedione and isoamyl alcohol. by orthology with RAW, OLRN-6 is predicted to inhibit JNK-1 signalling, which may in turn allow the asymmetrical AWC[ON] fate to emerge. [Source: WormBase]
C02C6.3C02C6.3aC02C6.3123 XReverseView as cDNA map |
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C02C6.3C02C6.3bC02C6.3123 XReverseView as cDNA map |
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C02D4.2C02D4.2aser-2323 XReverseView as cDNA map |
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ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase]
C02D4.2C02D4.2bser-2323 XReverseView as cDNA map |
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Ensembl
ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase]
C02D4.2C02D4.2eser-2323 XReverseView as cDNA map |
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Ensembl
ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase]
C02D4.2C02D4.2fser-2323 XReverseView as cDNA map |
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Ensembl
ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase]
C02F12.4C02F12.4tag-52523 XReverseView as cDNA map |
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C02F12.7C02F12.7tag-278223 XReverseView as cDNA map |
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C02F12.9C02F12.9C02F12.9123 XForwardView as cDNA map |
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C02H7.1C02H7.1dyf-11223 XForwardView as cDNA map |
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dyf-11 encodes a conserved protein orthologous to the human microtubule-binding protein MIP-T3 and that contains a lysine-rich region and a C-terminal coiled-coil domain present in a number of intraflagellar transport (IFT) complex B proteins. DYF-11 activity is required continuously in sensory neurons for formation of medial and distal ciliary segments and thus, for normal sensory cilium morphology and function and chemotaxis. a dyf-11::gfp promoter fusion is expressed in all ciliated sensory neurons as well as in the AQR, PQR, ADE, and PDR neurons. a DYF-11::GFP protein fusion is detected throughout the cilium and appears to localize to IFT-B particles in a manner consistent with an early role in IFT-B particle assembly. dyf-11 expression in ciliated neurons is dependent upon the presence of the DAF-19 RFX transcription factor. [Source: WormBase]
C02H7.2C02H7.2npr-19223 XReverseView as cDNA map |
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C02H7.3C02H7.3aaex-3623 XReverseView as cDNA map |
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aex-3 encodes a guanine nucleotide exchange factor for the rab-3 GTPase that is orthologous to human MAP kinase activating protein containing death domain (MADD, OMIM:603584). AEX-3 is required for intracellular vesicle trafficking as well as synaptic vesicle release and interacts with CAB-1 and RAB-3 to regulate separate pathways for neural activities such as defecation and male mating, respectively. AEX-3 is also required for egg laying and locomotion. AEX-3 is expressed in nearly all neurons. [Source: WormBase]
C03A3.2C03A3.2.1C03A3.2223 XForwardView as cDNA map |
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C03A3.2C03A3.2.2C03A3.2123 XForwardView as cDNA map |
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C03A3.3C03A3.3C03A3.3223 XReverseView as cDNA map |
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C03B1.12C03B1.12.1lmp-1223 XReverseView as cDNA map |
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lmp-1 encodes a protein with similarity to vertebrate lysosome-associated membrane proteins CD68, and appears to be the only protein in C. elegans that has a GYXX (phi) vertebrate lysosomal targeting sequence at its carboxy terminus. localized to the periphery of a large population of membrane bound organelles (granules) seen throughout the early embryos and restricted to the cells of the intestine during later stages. [Source: WormBase]
C03B1.12C03B1.12.2lmp-1123 XReverseView as cDNA map |
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lmp-1 encodes a protein with similarity to vertebrate lysosome-associated membrane proteins CD68, and appears to be the only protein in C. elegans that has a GYXX (phi) vertebrate lysosomal targeting sequence at its carboxy terminus. localized to the periphery of a large population of membrane bound organelles (granules) seen throughout the early embryos and restricted to the cells of the intestine during later stages. [Source: WormBase]
C03B1.1C03B1.1C03B1.1123 XForwardView as cDNA map |
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C03B1.4C03B1.4C03B1.4223 XForwardView as cDNA map |
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C03B1.5C03B1.5C03B1.5123 XForwardView as cDNA map |
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C03B1.9C03B1.9C03B1.9123 XReverseView as cDNA map |
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C03F11.1C03F11.1C03F11.1123 XForwardView as cDNA map |
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C03F11.3C03F11.3scav-1323 XReverseView as cDNA map |
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C03F11.4C03F11.4.1C03F11.4123 XReverseView as cDNA map |
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C03F11.4C03F11.4.2C03F11.4123 XReverseView as cDNA map |
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C03F11.4C03F11.4.3C03F11.4123 XReverseView as cDNA map |
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C03G5.10C03G5.10nspc-3123 XForwardView as cDNA map |
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C03G5.11C03G5.11nspc-4123 XReverseView as cDNA map |
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C03G5.12C03G5.12nspc-5123 XForwardView as cDNA map |
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C03G5.13C03G5.13nspc-6123 XReverseView as cDNA map |
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C03G5.1C03G5.1.1sdha-1123 XReverseView as cDNA map |
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sdha-1 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT A, FLAVOPROTEIN (SDHA. OMIM:600857), which when mutated leads to complex II mitochondrial respiratory chain deficiency presenting as Leigh syndrome. [Source: WormBase]
C03G5.1C03G5.1.2sdha-1123 XReverseView as cDNA map |
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sdha-1 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT A, FLAVOPROTEIN (SDHA. OMIM:600857), which when mutated leads to complex II mitochondrial respiratory chain deficiency presenting as Leigh syndrome. [Source: WormBase]
C03G5.7C03G5.7flp-5123 XForwardView as cDNA map |
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flp-5 encodes a predicted FMRFamide-like peptide neurotransmitter that increases action potential frequency in the pharyngeal muscle when applied to the pharynx of dissected worms. expressed in the sensory neurons ASE and PVM. [Source: WormBase]
C03G5.9C03G5.9nspc-2123 XForwardView as cDNA map |
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C03H12.1C03H12.1C03H12.1323 XForwardView as cDNA map |
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C04A11.1C04A11.1C04A11.1223 XForwardView as cDNA map |
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C04A11.2C04A11.2C04A11.2223 XReverseView as cDNA map |
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C04A11.3C04A11.3gck-4823 XForwardView as cDNA map |
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C04A11.4C04A11.4adm-2323 XForwardView as cDNA map |
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adm-2 encodes a protein containing a snake venom disintegrin-domain and a metalloprotease-like domain (i.e., a protein of the ADAM family). like ADM-1, ADM-2 is homologous to a mammalian sperm glycoprotein (PH-30/fertilin) implicated in sperm-egg fusion, and ADM-2 might thus be a fusogenic protein mediating the merging of plasma membranes during development. [Source: WormBase]
C04A11.5C04A11.5.1C04A11.5123 XForwardView as cDNA map |
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C04A11.5C04A11.5.2C04A11.5123 XForwardView as cDNA map |
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C04B4.1C04B4.1.1C04B4.1123 XForwardView as cDNA map |
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C04B4.1C04B4.1.2C04B4.1123 XForwardView as cDNA map |
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C04B4.3C04B4.3lips-2123 XForwardView as cDNA map |
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We gratefully acknowledge support of this work by the William M. Keck Foundation