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Genome: Caenorhabditis Elegans | mRNA | miRBase 18 (Nov. 2011), ENSEMBL 65 (Dec. 2011) and RNA22v1.0
Description: List of transcripts that are targeted by all of the below miRNA identifiers simultaneously
miRNA's: cel-miR-80-3p (MIMAT0000053)
Filtering By: Base pair min value: 12 | Folding energy max value (Kcal/mol): -21 | Min miRNA targets: 1


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Gene IDTranscript IDCommon Gene Name# of miRNA targets
for specified miRNAs
ChromosomeStrand DirectionTranscript Link to view miRNA target predictionsGene LinkDescription
AC8.12AC8.12AC8.12123 XForwardView as cDNA map |
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Ensembl
AC8.7AC8.7AC8.7123 XForwardView as cDNA map |
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Ensembl
AH9.4AH9.4AH9.4323 XReverseView as cDNA map |
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Ensembl
AH9.6AH9.6AH9.6123 XReverseView as cDNA map |
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Ensembl
AH9.6 encodes a novel protein that contains two predicted transmembrane domains and that is conserved in other nematode species. [Source: WormBase]
B0198.1B0198.1tsp-20123 XReverseView as cDNA map |
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Ensembl
B0198.2B0198.2aB0198.2123 XForwardView as cDNA map |
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Ensembl
B0198.2B0198.2bB0198.2123 XForwardView as cDNA map |
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Ensembl
B0198.3B0198.3aB0198.3123 XReverseView as cDNA map |
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B0272.1B0272.1tbb-4123 XReverseView as cDNA map |
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Ensembl
B0272.2B0272.2memb-1123 XReverseView as cDNA map |
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Ensembl
B0272.4B0272.4B0272.4123 XForwardView as cDNA map |
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Ensembl
B0294.1B0294.1B0294.1123 XReverseView as cDNA map |
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Ensembl
B0302.1B0302.1a.1kin-25623 XForwardView as cDNA map |
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Ensembl
kin-25 encodes a nonreceptor tyrosine kinase that is a member of the Ack subfamily of cytoplasmic tyrosine kinases. [Source: WormBase]
B0302.1B0302.1a.2kin-25623 XForwardView as cDNA map |
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Ensembl
kin-25 encodes a nonreceptor tyrosine kinase that is a member of the Ack subfamily of cytoplasmic tyrosine kinases. [Source: WormBase]
B0302.1B0302.1bkin-25523 XForwardView as cDNA map |
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Ensembl
kin-25 encodes a nonreceptor tyrosine kinase that is a member of the Ack subfamily of cytoplasmic tyrosine kinases. [Source: WormBase]
B0310.1B0310.1bB0310.1123 XForwardView as cDNA map |
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Ensembl
B0310.1 encodes a nematode-specific transmembrane protein. loss of B0310.1 activity via RNAi results in reduced fat content in wild-type and tub-1 mutant animals, suggesting that B0301.1 plays a role in lipid metabolism. [Source: WormBase]
B0310.2B0310.2.1B0310.2223 XReverseView as cDNA map |
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Ensembl
B0310.2B0310.2.2B0310.2123 XReverseView as cDNA map |
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B0310.3B0310.3B0310.3123 XReverseView as cDNA map |
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B0310.5B0310.5ugt-46323 XReverseView as cDNA map |
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Ensembl
B0344.2B0344.2wrt-9123 XForwardView as cDNA map |
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Ensembl
wrt-9 encodes a hedgehog-like protein, with an N-terminal signal sequence, a Wart domain, and a C-terminal region of proline-rich, low-complexity sequence. the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins. WRT-9 has no obvious function in RNAi assays. [Source: WormBase]
B0395.2B0395.2mboa-1223 XForwardView as cDNA map |
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Ensembl
mboa-1 encodes a putative acyl-Coenzyme A:cholesterol ('sterol') O-acyltransferase, orthologous to human SOAT1 (OMIM:102642). MBOA-1 is required for normal locomotion and normally long lifespan in mass RNAi assays. mboa-1 is expressed in the seam cells and nervous systems of larvae and adults, and in the adult reproductive system. [Source: WormBase]
B0395.3B0395.3.1B0395.3323 XReverseView as cDNA map |
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B0395.3 is orthologous to the human gene CHOLINE ACETYLTRANSFERASE ISOFORM R (CHAT. OMIM:118490), which when mutated leads to disease. [Source: WormBase]
B0395.3B0395.3.2B0395.3223 XReverseView as cDNA map |
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Ensembl
B0395.3 is orthologous to the human gene CHOLINE ACETYLTRANSFERASE ISOFORM R (CHAT. OMIM:118490), which when mutated leads to disease. [Source: WormBase]
B0403.2B0403.2ubc-17123 XForwardView as cDNA map |
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B0403.3B0403.3B0403.3123 XReverseView as cDNA map |
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B0403.4B0403.4tag-320123 XReverseView as cDNA map |
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B0403.5B0403.5B0403.5223 XForwardView as cDNA map |
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B0416.1B0416.1B0416.1123 XForwardView as cDNA map |
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B0416.3B0416.3B0416.3123 XForwardView as cDNA map |
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B0416.5B0416.5aB0416.5323 XReverseView as cDNA map |
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B0416.5B0416.5bB0416.5123 XReverseView as cDNA map |
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B0563.4B0563.4.1tmbi-4123 XForwardView as cDNA map |
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B0563.4B0563.4.2tmbi-4123 XForwardView as cDNA map |
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B0563.6B0563.6aB0563.6123 XForwardView as cDNA map |
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B0563.6B0563.6b.1B0563.6123 XForwardView as cDNA map |
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B0563.6B0563.6b.2B0563.6123 XForwardView as cDNA map |
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B0563.6B0563.6cB0563.6123 XForwardView as cDNA map |
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B0563.7B0563.7B0563.7123 XReverseView as cDNA map |
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B0563.9B0563.9B0563.9123 XForwardView as cDNA map |
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C01C10.1C01C10.1clc-2223 XForwardView as cDNA map |
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clc-2 encodes a claudin homolog, closely similar to CLC-1, that is required for normal cohesion of apical junctions in epithelia. claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water. CLC-2 maintains the impermeability ('barrier function') of epithelia, since clc-1(RNAi) animals have abnormal permeability of the hypodermis to dyes. clc-2 is expressed in hypodermal seam cells, with two diffuse lines of CLC-2 protein. [Source: WormBase]
C01C10.3C01C10.3.1acl-12223 XReverseView as cDNA map |
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Ensembl
C01C10.3C01C10.3.2acl-12223 XReverseView as cDNA map |
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C01C10.4C01C10.4clc-5223 XForwardView as cDNA map |
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clc-5 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia. CLC-5 is worm-specific, with obvious homologs only in C. elegans. CLC-5 has no obvious function in mass RNAi assays. claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water. [Source: WormBase]
C02B4.1C02B4.1adt-1423 XForwardView as cDNA map |
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The adt-1 gene encodes a metalloproteinase with disintegrin-like and metalloproteinase with thrombospondin type I motifs (ADAMTS) that is required for male tail morphogenesis. [Source: WormBase]
C02B8.2C02B8.2fbxc-38123 XForwardView as cDNA map |
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Ensembl
C02C6.1C02C6.1adyn-1423 XForwardView as cDNA map |
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dyn-1 encodes the C. elegans ortholog of the dynamin GTPase. dyn-1 activity is required for endocytosis, synaptic vesicle recycling, cytokinesis, and the CED-1 pathway that regulates engulfment and degradation of apoptotic cells. mutations in dyn-1 affect locomotion, egg-laying, defecation, and embryonic development, indicating that dyn-1's endocytic function is required for a number of diverse processes. dyn-1 reporter fusion constructs are expressed in motor neurons, intestinal cells, and pharyngeal muscle. [Source: WormBase]
C02C6.1C02C6.1bdyn-1423 XForwardView as cDNA map |
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Ensembl
dyn-1 encodes the C. elegans ortholog of the dynamin GTPase. dyn-1 activity is required for endocytosis, synaptic vesicle recycling, cytokinesis, and the CED-1 pathway that regulates engulfment and degradation of apoptotic cells. mutations in dyn-1 affect locomotion, egg-laying, defecation, and embryonic development, indicating that dyn-1's endocytic function is required for a number of diverse processes. dyn-1 reporter fusion constructs are expressed in motor neurons, intestinal cells, and pharyngeal muscle. [Source: WormBase]
C02C6.2C02C6.2aolrn-1123 XForwardView as cDNA map |
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Ensembl
olrn-1 encodes, by alternative splicing, two isoforms of a transmembrane protein required for differentiation of the AWC[ON] neuron, expression of str-2 in AWC[ON], adaptation to benzaldehyde, chemotaxis to butanone, and enhancement of chemotaxis to butanone by the presence of food. OLRN-1 is orthologous to Drosophila melanogaster RAW and Schistosoma japonicum SJCHGC05616. while OLRN-1 has orthologs in nematodes, trematodes, and arthropods, its has no obvious chordate homologs. OLRN-6 is expressed in many pharyngeal neurons and some head neurons, but is required solely in the AWC[ON] neuron for butanone enhancement. OLRN-6's function in butanone enhancement is both serotonin- and dopamine-independent, and appears to also act in chemotactic enhancement of 2,3-pentanedione and isoamyl alcohol. by orthology with RAW, OLRN-6 is predicted to inhibit JNK-1 signalling, which may in turn allow the asymmetrical AWC[ON] fate to emerge. [Source: WormBase]
C02C6.3C02C6.3aC02C6.3223 XReverseView as cDNA map |
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Ensembl
C02C6.3C02C6.3bC02C6.3123 XReverseView as cDNA map |
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Ensembl
C02D4.1C02D4.1jud-4123 XForwardView as cDNA map |
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Ensembl
jud-4 encodes an unfamiliar protein, putatively secreted, that is required both for normal sensitivity to ethanol and for survival after freezing and thawing. JUD-4 is expressed in hypodermis and vulval muscles. JUD-4 is orthologous to Brugia malayi Bm1_40315, but lacks obvious orthologies to non-nematode proteins. JUD-4's C-terminal domain has possible similarity to F40E10.5, and to proteins such as human HOMER1. jud-4(ys18) mutants show delayed sensitivity to ethanol levels that rapidly paralyze normal worms, but do not survive freezing and rethawing as does wild-type. JUD-4 has no obvious function in mass RNAi assays. [Source: WormBase]
C02D4.2C02D4.2fser-2123 XReverseView as cDNA map |
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Ensembl
ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase]
C02F12.10C02F12.10C02F12.10123 XReverseView as cDNA map |
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C02F12.10 encodes a homeobox protein of uncertain affinity, but with some similarity to vertebrate Hox3 proteins and the D. melanogster homeobox protein ROUGH. C02F12.10 is expressed in a single tail neuron of hermaphrodites from late embryo to adult stages, as well as in a uterus cell separate from the vulva (perhaps in the spermetheca). C02F12.10 has no obvious function in mass RNAi assays. [Source: WormBase]
C02F12.1C02F12.1atsp-17123 XForwardView as cDNA map |
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C02F12.1C02F12.1btsp-17123 XForwardView as cDNA map |
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C02F12.4C02F12.4tag-52123 XReverseView as cDNA map |
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C02F12.7C02F12.7tag-278123 XReverseView as cDNA map |
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C02F12.8C02F12.8C02F12.8123 XReverseView as cDNA map |
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C02H7.2C02H7.2npr-19123 XReverseView as cDNA map |
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Ensembl
C02H7.3C02H7.3aaex-3123 XReverseView as cDNA map |
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aex-3 encodes a guanine nucleotide exchange factor for the rab-3 GTPase that is orthologous to human MAP kinase activating protein containing death domain (MADD, OMIM:603584). AEX-3 is required for intracellular vesicle trafficking as well as synaptic vesicle release and interacts with CAB-1 and RAB-3 to regulate separate pathways for neural activities such as defecation and male mating, respectively. AEX-3 is also required for egg laying and locomotion. AEX-3 is expressed in nearly all neurons. [Source: WormBase]
C03A3.2C03A3.2.1C03A3.2123 XForwardView as cDNA map |
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C03A3.2C03A3.2.2C03A3.2123 XForwardView as cDNA map |
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C03B1.12C03B1.12.1lmp-1123 XReverseView as cDNA map |
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lmp-1 encodes a protein with similarity to vertebrate lysosome-associated membrane proteins CD68, and appears to be the only protein in C. elegans that has a GYXX (phi) vertebrate lysosomal targeting sequence at its carboxy terminus. localized to the periphery of a large population of membrane bound organelles (granules) seen throughout the early embryos and restricted to the cells of the intestine during later stages. [Source: WormBase]
C03B1.13C03B1.13C03B1.13123 XReverseView as cDNA map |
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C03B1.2C03B1.2C03B1.2123 XForwardView as cDNA map |
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C03B1.7C03B1.7C03B1.7123 XForwardView as cDNA map |
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C03F11.2C03F11.2C03F11.2223 XReverseView as cDNA map |
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C03F11.3C03F11.3scav-1223 XReverseView as cDNA map |
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C03G5.1C03G5.1.1sdha-1423 XReverseView as cDNA map |
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sdha-1 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT A, FLAVOPROTEIN (SDHA. OMIM:600857), which when mutated leads to complex II mitochondrial respiratory chain deficiency presenting as Leigh syndrome. [Source: WormBase]
C03G5.1C03G5.1.2sdha-1423 XReverseView as cDNA map |
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sdha-1 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT A, FLAVOPROTEIN (SDHA. OMIM:600857), which when mutated leads to complex II mitochondrial respiratory chain deficiency presenting as Leigh syndrome. [Source: WormBase]
C03H12.1C03H12.1C03H12.1223 XForwardView as cDNA map |
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C04A11.1C04A11.1C04A11.1123 XForwardView as cDNA map |
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C04A11.2C04A11.2C04A11.2423 XReverseView as cDNA map |
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C04A11.3C04A11.3gck-4323 XForwardView as cDNA map |
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C04A11.4C04A11.4adm-2623 XForwardView as cDNA map |
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adm-2 encodes a protein containing a snake venom disintegrin-domain and a metalloprotease-like domain (i.e., a protein of the ADAM family). like ADM-1, ADM-2 is homologous to a mammalian sperm glycoprotein (PH-30/fertilin) implicated in sperm-egg fusion, and ADM-2 might thus be a fusogenic protein mediating the merging of plasma membranes during development. [Source: WormBase]
C04B4.2C04B4.2C04B4.2223 XForwardView as cDNA map |
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C04B4.4C04B4.4C04B4.4323 XForwardView as cDNA map |
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C04B4.5C04B4.5C04B4.5223 XReverseView as cDNA map |
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C04B4.5 encodes a novel protein. [Source: WormBase]
C04C11.2C04C11.2.1arrd-25123 XForwardView as cDNA map |
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C04C11.2C04C11.2.2arrd-25123 XForwardView as cDNA map |
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C04E7.1C04E7.1C04E7.1123 XForwardView as cDNA map |
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C04E7.3C04E7.3C04E7.3223 XReverseView as cDNA map |
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C04E7.4C04E7.4C04E7.4223 XReverseView as cDNA map |
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C04F6.1C04F6.1vit-5223 XForwardView as cDNA map |
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vit-5 encodes a vitellogenin, a lipid-binding protein precursor related to vertebrate vitellogenins and mammalian ApoB-100, a core LDL particle constituent. by homology, VIT-5 is predicted to function as a lipid transport protein. loss of vit-5 activity via large-scale RNA-mediated interference (RNAi) screens indicates that VIT-5 is required for embryogenesis and normal rates of postembryonic growth. VIT-5 is a major yolk component and is expressed exclusively in the adult hermaphrodite intestine from which it is secreted into the pseudocoelomic space and taken up by oocytes. [Source: WormBase]
C04F6.5C04F6.5dhs-27123 XReverseView as cDNA map |
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dhs-27 encodes a short-chain dehydrogenase predicted to be mitochondrial. [Source: WormBase]
C04F6.7C04F6.7C04F6.7123 XReverseView as cDNA map |
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C05A9.1C05A9.1apgp-5323 XReverseView as cDNA map |
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pgp-5 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily. by homology, PGP-5 is predicted to function as an ATP-dependent efflux pump that protects C. elegans by exporting exogenous toxins. however, as loss of pgp-5 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of PGP-5 in C. elegans development and/or behavior is not yet known. [Source: WormBase]
C05A9.1C05A9.1bpgp-5323 XReverseView as cDNA map |
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pgp-5 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily. by homology, PGP-5 is predicted to function as an ATP-dependent efflux pump that protects C. elegans by exporting exogenous toxins. however, as loss of pgp-5 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of PGP-5 in C. elegans development and/or behavior is not yet known. [Source: WormBase]
C05A9.2C05A9.2C05A9.2223 XReverseView as cDNA map |
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C05C9.1C05C9.1C05C9.1123 XForwardView as cDNA map |
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C05C9.3C05C9.3C05C9.3223 XReverseView as cDNA map |
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The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77). [Source: WormBase]
C05D9.1C05D9.1.1snx-1123 XForwardView as cDNA map |
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C05D9.1C05D9.1.2snx-1123 XForwardView as cDNA map |
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C05D9.1C05D9.1.3snx-1123 XForwardView as cDNA map |
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C05D9.3C05D9.3C05D9.3123 XForwardView as cDNA map |
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C05D9.4C05D9.4C05D9.4123 XForwardView as cDNA map |
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C05D9.7C05D9.7C05D9.7123 XReverseView as cDNA map |
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C05E11.3C05E11.3C05E11.3123 XForwardView as cDNA map |
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C05E11.4C05E11.4amt-1223 XForwardView as cDNA map |
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amt-1 encodes a transmembrane transporter that by homology, is predicted to transport ammonium ions across the plasma membrane. as loss of amt-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of AMT-1 in C. elegans development and/or behavior is not yet known. [Source: WormBase]
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GUI created by the Computational Medicine Center at the Sidney Kimmel Medical College of Thomas Jefferson University
We gratefully acknowledge support of this work by the William M. Keck Foundation