microRNASeq

Gene ID	Transcript ID	Common Gene Name	# of miRNA targets for specified miRNAs	Chromosome	Strand Direction	Transcript Link to view miRNA target predictions	Gene Link	Description
AH9.1	AH9.1	AH9.1	2	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
B0198.2	B0198.2a	B0198.2	2	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
B0198.2	B0198.2b	B0198.2	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
B0198.3	B0198.3a	B0198.3	3	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
B0272.4	B0272.4	B0272.4	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
B0310.2	B0310.2.1	B0310.2	2	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
B0310.2	B0310.2.2	B0310.2	2	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
B0344.2	B0344.2	wrt-9	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl	wrt-9 encodes a hedgehog-like protein, with an N-terminal signal sequence, a Wart domain, and a C-terminal region of proline-rich, low-complexity sequence. the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins. WRT-9 has no obvious function in RNAi assays. [Source: WormBase]
B0403.5	B0403.5	B0403.5	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
B0410.1	B0410.1	B0410.1	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
B0410.2	B0410.2a	vang-1	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl	vang-1 encodes an ortholog of Drosophila VAN GOGH (also known as STRABISMUS). VANG-1 enables Wnt-directed planar cell polarity. VANG-1 is required for the fully asymmetrical division of B.a versus B.p cells, though this requirement is quantitatively weak. [Source: WormBase]
B0416.5	B0416.5a	B0416.5	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
B0416.6	B0416.6	gly-13	4	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl	gly-13 encodes an experimentally verified UDP-N-acetylglucosamine alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I (GnT I), that is the primary GnT I enzyme in vivo, and that can act on unusual substrates. gly-13 is expressed throughout development in many cell types. gly-13 has no obvious function in vivo, since a deletion allele of gly-13 is phenotypically normal even as a double or triple mutant with gly-12 and gly-14. [Source: WormBase]
B0563.1	B0563.1	B0563.1	2	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C01C10.2	C01C10.2b	C01C10.2	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
C01C10.3	C01C10.3.1	acl-12	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
C01C10.3	C01C10.3.2	acl-12	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
C02B4.1	C02B4.1	adt-1	2	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl	The adt-1 gene encodes a metalloproteinase with disintegrin-like and metalloproteinase with thrombospondin type I motifs (ADAMTS) that is required for male tail morphogenesis. [Source: WormBase]
C02D4.2	C02D4.2a	ser-2	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl	ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase]
C02D4.2	C02D4.2e	ser-2	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl	ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase]
C02F12.1	C02F12.1a	tsp-17	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C02F12.1	C02F12.1b	tsp-17	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C02F12.7	C02F12.7	tag-278	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
C02H7.2	C02H7.2	npr-19	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
C02H7.3	C02H7.3a	aex-3	6	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl	aex-3 encodes a guanine nucleotide exchange factor for the rab-3 GTPase that is orthologous to human MAP kinase activating protein containing death domain (MADD, OMIM:603584). AEX-3 is required for intracellular vesicle trafficking as well as synaptic vesicle release and interacts with CAB-1 and RAB-3 to regulate separate pathways for neural activities such as defecation and male mating, respectively. AEX-3 is also required for egg laying and locomotion. AEX-3 is expressed in nearly all neurons. [Source: WormBase]
C03A3.1	C03A3.1b	C03A3.1	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C03A3.2	C03A3.2.1	C03A3.2	2	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C03A3.2	C03A3.2.2	C03A3.2	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C03B1.2	C03B1.2	C03B1.2	2	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C03B1.3	C03B1.3	C03B1.3	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C03B1.4	C03B1.4	C03B1.4	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C03B1.7	C03B1.7	C03B1.7	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C03G5.1	C03G5.1.1	sdha-1	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl	sdha-1 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT A, FLAVOPROTEIN (SDHA. OMIM:600857), which when mutated leads to complex II mitochondrial respiratory chain deficiency presenting as Leigh syndrome. [Source: WormBase]
C03G5.1	C03G5.1.2	sdha-1	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl	sdha-1 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT A, FLAVOPROTEIN (SDHA. OMIM:600857), which when mutated leads to complex II mitochondrial respiratory chain deficiency presenting as Leigh syndrome. [Source: WormBase]
C04A11.3	C04A11.3	gck-4	3	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C04A11.5	C04A11.5.1	C04A11.5	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C04A11.5	C04A11.5.2	C04A11.5	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C04B4.4	C04B4.4	C04B4.4	2	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C04C11.2	C04C11.2.1	arrd-25	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C04F6.1	C04F6.1	vit-5	2	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl	vit-5 encodes a vitellogenin, a lipid-binding protein precursor related to vertebrate vitellogenins and mammalian ApoB-100, a core LDL particle constituent. by homology, VIT-5 is predicted to function as a lipid transport protein. loss of vit-5 activity via large-scale RNA-mediated interference (RNAi) screens indicates that VIT-5 is required for embryogenesis and normal rates of postembryonic growth. VIT-5 is a major yolk component and is expressed exclusively in the adult hermaphrodite intestine from which it is secreted into the pseudocoelomic space and taken up by oocytes. [Source: WormBase]
C04F6.3	C04F6.3.1	cht-1	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl	cht-1 encodes a chitinase orthologous to human chitinase-1 (OMIM:600031, mutations are associated with chitotriosidase deficiency). CHT-1 is predicted to function as an extracellular O-glycosyl hydrolase that hydrolyzes the glycosidic bond between two or more carbohydrates. in C. elegans, CHT-1 may play a role in embryogenesis, and may also be required for cuticle degradation during molting and degradation of chitin-containing pathogens as part of a host defense mechanism. [Source: WormBase]
C04F6.3	C04F6.3.2	cht-1	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl	cht-1 encodes a chitinase orthologous to human chitinase-1 (OMIM:600031, mutations are associated with chitotriosidase deficiency). CHT-1 is predicted to function as an extracellular O-glycosyl hydrolase that hydrolyzes the glycosidic bond between two or more carbohydrates. in C. elegans, CHT-1 may play a role in embryogenesis, and may also be required for cuticle degradation during molting and degradation of chitin-containing pathogens as part of a host defense mechanism. [Source: WormBase]
C04F6.4	C04F6.4a	unc-78	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl	The unc-78 gene encodes a homolog of actin-interacting protein 1 (AIP1) that regulates the ordered assembly of actin and cofilin in myofibrils. [Source: WormBase]
C05A9.1	C05A9.1a	pgp-5	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl	pgp-5 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily. by homology, PGP-5 is predicted to function as an ATP-dependent efflux pump that protects C. elegans by exporting exogenous toxins. however, as loss of pgp-5 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of PGP-5 in C. elegans development and/or behavior is not yet known. [Source: WormBase]
C05A9.1	C05A9.1b	pgp-5	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl	pgp-5 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily. by homology, PGP-5 is predicted to function as an ATP-dependent efflux pump that protects C. elegans by exporting exogenous toxins. however, as loss of pgp-5 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of PGP-5 in C. elegans development and/or behavior is not yet known. [Source: WormBase]
C05A9.2	C05A9.2	C05A9.2	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
C05C9.1	C05C9.1	C05C9.1	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C05C9.3	C05C9.3	C05C9.3	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77). [Source: WormBase]
C05E11.3	C05E11.3	C05E11.3	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C05E11.4	C05E11.4	amt-1	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl	amt-1 encodes a transmembrane transporter that by homology, is predicted to transport ammonium ions across the plasma membrane. as loss of amt-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of AMT-1 in C. elegans development and/or behavior is not yet known. [Source: WormBase]
C05E11.5	C05E11.5	amt-4	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl	amt-4 encodes a member of the ammonium transporter protein family. [Source: WormBase]
C05E11.7	C05E11.7	C05E11.7	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
C05G5.2	C05G5.2	C05G5.2	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C06G1.1	C06G1.1a	C06G1.1	2	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C06G1.1	C06G1.1b	C06G1.1	2	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C06G1.5	C06G1.5	C06G1.5	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
C07A12.1	C07A12.1a	ham-2	2	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl	The ham-2 gene encodes a C2H2 zinc finger-containing protein required for proper migration of the hermaphrodite-specific neurons (HSNs) and proper attachment of the pharynx to the nose. HAM-2 is expressed in the nuclei of the HSNs during migration, and acts downstream of EGL-5, a posterior group Hox protein, in HSN specification. HAM-2 acts redundantly with UNC-86 to downregulate UNC-43 expression in the HSNs after migration is complete. [Source: WormBase]
C07A12.1	C07A12.1b	ham-2	2	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl	The ham-2 gene encodes a C2H2 zinc finger-containing protein required for proper migration of the hermaphrodite-specific neurons (HSNs) and proper attachment of the pharynx to the nose. HAM-2 is expressed in the nuclei of the HSNs during migration, and acts downstream of EGL-5, a posterior group Hox protein, in HSN specification. HAM-2 acts redundantly with UNC-86 to downregulate UNC-43 expression in the HSNs after migration is complete. [Source: WormBase]
C07A12.1	C07A12.1c	ham-2	2	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl	The ham-2 gene encodes a C2H2 zinc finger-containing protein required for proper migration of the hermaphrodite-specific neurons (HSNs) and proper attachment of the pharynx to the nose. HAM-2 is expressed in the nuclei of the HSNs during migration, and acts downstream of EGL-5, a posterior group Hox protein, in HSN specification. HAM-2 acts redundantly with UNC-86 to downregulate UNC-43 expression in the HSNs after migration is complete. [Source: WormBase]
C07A4.1	C07A4.1	tiar-3	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C07B5.5	C07B5.5	nuc-1	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl	The nuc-1 gene encodes a DNase II homolog similar to mammalian and Drosophila DNaseII enzymes and is required for DNA degradation during apoptosis as well as for degradation of dietary DNA during normal feeding. during apoptosis, NUC-1 functions in apoptotic cells at an intermediate stage of DNA degradation, after the killing step, but prior to cell-corpse engulfment. [Source: WormBase]
C08A9.9	C08A9.9.1	C08A9.9	2	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
C08A9.9	C08A9.9.2	C08A9.9	2	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
C09B8.1	C09B8.1	ipp-5	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl	ipp-5 encodes a type I inositol 5-phosphatase homolog. ipp-5 acts downstream of let-23 to negatively regulate IP3 signaling and is involved in spermathecal contractions during ovulation. an ipp-5::gfp transcriptional reporter is expressed in the adult distal spermatheca and weakly in the proximal sheath. [Source: WormBase]
C09B8.5	C09B8.5	C09B8.5	3	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
C09G1.2	C09G1.2	C09G1.2	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
C10A4.1	C10A4.1	C10A4.1	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C10A4.9	C10A4.9	C10A4.9	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C10E2.3	C10E2.3	hda-4	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl	hda-4 encodes a class II histone deacetylase that contains a putative MEF-2 DNA binding domain, a nuclear localization signal domain, and a single catalytic domain and may affect locomotion, body morphology, and growth. interacts with MEF-2 in in vitro assays and is expressed in body-wall muscle, neurons, and hypodermal seam cells [Source: WormBase]
C10E2.6	C10E2.6.1	C10E2.6	2	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
C10E2.6	C10E2.6.2	C10E2.6	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
C11E4.6	C11E4.6.1	C11E4.6	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C11E4.6	C11E4.6.2	C11E4.6	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C11G6.3	C11G6.3	C11G6.3	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl	C11G6.3 encodes a plant homeodomain-containing protein that is related to the ING (Inhibitor of Growth) family of proteins that function in regulation of gene expression and are candidate tumor suppressors. [Source: WormBase]
C11G6.4	C11G6.4a	nhr-28	2	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C11H1.3	C11H1.3	C11H1.3	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
C11H1.4	C11H1.4a	prx-1	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl	prx-1 encodes a predicted peroxin, a subfamily 2 member of the AAA (ATPases Associated with diverse cellular Activities) family that affects growth in one large-scale RNAi screen. expressed in intestinal cells throughout development. [Source: WormBase]
C12D12.2	C12D12.2a.1	glt-1	2	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl	glt-1 encodes a predicted plasma membrane glutamate transporter that is functional when expressed in Xenopus oocytes. expressed in the M3 pharyngeal neuron, the male tail, some anterior hypodermal cells, and in cells in the terminal bulb of the pharynx. [Source: WormBase]
C12D12.2	C12D12.2a.2	glt-1	2	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl	glt-1 encodes a predicted plasma membrane glutamate transporter that is functional when expressed in Xenopus oocytes. expressed in the M3 pharyngeal neuron, the male tail, some anterior hypodermal cells, and in cells in the terminal bulb of the pharynx. [Source: WormBase]
C12D12.5	C12D12.5	sox-4	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
C13E3.1	C13E3.1	C13E3.1	2	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C14A11.3	C14A11.3a	cgef-1	2	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C14A11.3	C14A11.3b	cgef-1	2	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C14A11.3	C14A11.3c	cgef-1	2	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C14F11.6	C14F11.6.1	C14F11.6	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
C14F11.6	C14F11.6.2	C14F11.6	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
C15A7.2	C15A7.2	C15A7.2	2	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
C15B12.2	C15B12.2.1	C15B12.2	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C15B12.2	C15B12.2.2	C15B12.2	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C15B12.4	C15B12.4	C15B12.4	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl
C15B12.7	C15B12.7b	cdf-1	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl	a cation diffusion facilitator protein, affects vulva development, genetically interacts with let-60/ras signaling pathway. and is expressed in the vulval muscles, the intestinal cells, and in the vulval precursor cells. [Source: WormBase]
C15C7.2	C15C7.2.1	klp-8	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl	klp-8 encodes an atypical kinesin-like motor protein with the motor domain in the N-terminus. the motor domain of KLP-8 exhibits poor homology to the globular motor domain of the kinesin heavy chain. [Source: WormBase]
C15C7.2	C15C7.2.2	klp-8	1	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl	klp-8 encodes an atypical kinesin-like motor protein with the motor domain in the N-terminus. the motor domain of KLP-8 exhibits poor homology to the globular motor domain of the kinesin heavy chain. [Source: WormBase]
C15H9.1	C15H9.1	nnt-1	3	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl	nnt-1 encodes a proton-pumping nicotinamide nucleotide transhydrogenase predicted to be mitochondrial. [Source: WormBase]
C15H9.5	C15H9.5.1	C15H9.5	3	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C15H9.5	C15H9.5.2	C15H9.5	3	23 X	Forward	View as cDNA map \| View as Table	Internal \| Ensembl
C15H9.6	C15H9.6.1	hsp-3	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl	hsp-3 encodes one of two C. elegans heat shock response 70 (hsp70) proteins homologous to mammalian grp78/BiP (glucose regulated protein 78/immunoglobulin heavy chain-binding protein, OMIM:138120). HSP-3 likely functions as a molecular chaperone, and is expressed constitutively (expression is not heat inducible) throughout development with greatest abundance during the L1 larval stage. hsp-3 transcription is, however, upregulated in response to endoplasmic reticulum stress induced by dithiothreitol (DTT) or tunicamycin. HSP-3 contains a long hydrophobic amino terminus and a carboxyl terminal KDEL sequence suggesting that it may be retained in the endoplasmic reticulum. [Source: WormBase]
C15H9.6	C15H9.6.2	hsp-3	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl	hsp-3 encodes one of two C. elegans heat shock response 70 (hsp70) proteins homologous to mammalian grp78/BiP (glucose regulated protein 78/immunoglobulin heavy chain-binding protein, OMIM:138120). HSP-3 likely functions as a molecular chaperone, and is expressed constitutively (expression is not heat inducible) throughout development with greatest abundance during the L1 larval stage. hsp-3 transcription is, however, upregulated in response to endoplasmic reticulum stress induced by dithiothreitol (DTT) or tunicamycin. HSP-3 contains a long hydrophobic amino terminus and a carboxyl terminal KDEL sequence suggesting that it may be retained in the endoplasmic reticulum. [Source: WormBase]
C15H9.6	C15H9.6.3	hsp-3	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl	hsp-3 encodes one of two C. elegans heat shock response 70 (hsp70) proteins homologous to mammalian grp78/BiP (glucose regulated protein 78/immunoglobulin heavy chain-binding protein, OMIM:138120). HSP-3 likely functions as a molecular chaperone, and is expressed constitutively (expression is not heat inducible) throughout development with greatest abundance during the L1 larval stage. hsp-3 transcription is, however, upregulated in response to endoplasmic reticulum stress induced by dithiothreitol (DTT) or tunicamycin. HSP-3 contains a long hydrophobic amino terminus and a carboxyl terminal KDEL sequence suggesting that it may be retained in the endoplasmic reticulum. [Source: WormBase]
C16B8.2	C16B8.2.2	C16B8.2	1	23 X	Reverse	View as cDNA map \| View as Table	Internal \| Ensembl

Gene ID

Transcript ID

Common Gene Name

# of miRNA targets
for specified miRNAs

Chromosome

Strand Direction

Transcript Link to view miRNA target predictions

Gene Link

Description

AH9.1

23 X

Reverse

View as cDNA map |
View as Table

Internal |
Ensembl

B0198.2

B0198.2a

B0198.2

23 X

Forward

View as cDNA map |
View as Table

Internal |
Ensembl

B0198.2

B0198.2b

B0198.2

23 X

Forward

View as cDNA map |
View as Table

Internal |
Ensembl

B0198.3

B0198.3a

B0198.3

23 X

Reverse

View as cDNA map |
View as Table

Internal |
Ensembl

B0272.4

23 X

Forward

View as cDNA map |
View as Table

Internal |
Ensembl

B0310.2

B0310.2.1

B0310.2

23 X

Reverse

View as cDNA map |
View as Table

Internal |
Ensembl

B0310.2

B0310.2.2

B0310.2

23 X

Reverse

View as cDNA map |
View as Table

Internal |
Ensembl

B0344.2

wrt-9

23 X

Forward

View as cDNA map |
View as Table

Internal |
Ensembl

wrt-9 encodes a hedgehog-like protein, with an N-terminal signal sequence, a Wart domain, and a C-terminal region of proline-rich, low-complexity sequence. the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins. WRT-9 has no obvious function in RNAi assays. [Source: WormBase]

B0403.5

23 X

Forward

View as cDNA map |
View as Table

Internal |
Ensembl

B0410.1

23 X

Forward

View as cDNA map |
View as Table

Internal |
Ensembl

B0410.2

B0410.2a

vang-1

23 X

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vang-1 encodes an ortholog of Drosophila VAN GOGH (also known as STRABISMUS). VANG-1 enables Wnt-directed planar cell polarity. VANG-1 is required for the fully asymmetrical division of B.a versus B.p cells, though this requirement is quantitatively weak. [Source: WormBase]

B0416.5

B0416.5a

B0416.5

23 X

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B0416.6

gly-13

23 X

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gly-13 encodes an experimentally verified UDP-N-acetylglucosamine alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I (GnT I), that is the primary GnT I enzyme in vivo, and that can act on unusual substrates. gly-13 is expressed throughout development in many cell types. gly-13 has no obvious function in vivo, since a deletion allele of gly-13 is phenotypically normal even as a double or triple mutant with gly-12 and gly-14. [Source: WormBase]

B0563.1

23 X

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C01C10.2

C01C10.2b

C01C10.2

23 X

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C01C10.3

C01C10.3.1

acl-12

23 X

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C01C10.3

C01C10.3.2

acl-12

23 X

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C02B4.1

adt-1

23 X

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The adt-1 gene encodes a metalloproteinase with disintegrin-like and metalloproteinase with thrombospondin type I motifs (ADAMTS) that is required for male tail morphogenesis. [Source: WormBase]

C02D4.2

C02D4.2a

ser-2

23 X

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ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase]

C02D4.2

C02D4.2e

ser-2

23 X

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C02F12.1

C02F12.1a

tsp-17

23 X

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C02F12.1

C02F12.1b

tsp-17

23 X

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C02F12.7

tag-278

23 X

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C02H7.2

npr-19

23 X

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C02H7.3

C02H7.3a

aex-3

23 X

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aex-3 encodes a guanine nucleotide exchange factor for the rab-3 GTPase that is orthologous to human MAP kinase activating protein containing death domain (MADD, OMIM:603584). AEX-3 is required for intracellular vesicle trafficking as well as synaptic vesicle release and interacts with CAB-1 and RAB-3 to regulate separate pathways for neural activities such as defecation and male mating, respectively. AEX-3 is also required for egg laying and locomotion. AEX-3 is expressed in nearly all neurons. [Source: WormBase]

C03A3.1

C03A3.1b

C03A3.1

23 X

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C03A3.2

C03A3.2.1

C03A3.2

23 X

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C03A3.2

C03A3.2.2

C03A3.2

23 X

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C03B1.2

23 X

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C03B1.3

23 X

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C03B1.4

23 X

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C03B1.7

23 X

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C03G5.1

C03G5.1.1

sdha-1

23 X

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sdha-1 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT A, FLAVOPROTEIN (SDHA. OMIM:600857), which when mutated leads to complex II mitochondrial respiratory chain deficiency presenting as Leigh syndrome. [Source: WormBase]

C03G5.1

C03G5.1.2

sdha-1

23 X

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C04A11.3

gck-4

23 X

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C04A11.5

C04A11.5.1

C04A11.5

23 X

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C04A11.5

C04A11.5.2

C04A11.5

23 X

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C04B4.4

23 X

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C04C11.2

C04C11.2.1

arrd-25

23 X

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C04F6.1

vit-5

23 X

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vit-5 encodes a vitellogenin, a lipid-binding protein precursor related to vertebrate vitellogenins and mammalian ApoB-100, a core LDL particle constituent. by homology, VIT-5 is predicted to function as a lipid transport protein. loss of vit-5 activity via large-scale RNA-mediated interference (RNAi) screens indicates that VIT-5 is required for embryogenesis and normal rates of postembryonic growth. VIT-5 is a major yolk component and is expressed exclusively in the adult hermaphrodite intestine from which it is secreted into the pseudocoelomic space and taken up by oocytes. [Source: WormBase]

C04F6.3

C04F6.3.1

cht-1

23 X

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cht-1 encodes a chitinase orthologous to human chitinase-1 (OMIM:600031, mutations are associated with chitotriosidase deficiency). CHT-1 is predicted to function as an extracellular O-glycosyl hydrolase that hydrolyzes the glycosidic bond between two or more carbohydrates. in C. elegans, CHT-1 may play a role in embryogenesis, and may also be required for cuticle degradation during molting and degradation of chitin-containing pathogens as part of a host defense mechanism. [Source: WormBase]

C04F6.3

C04F6.3.2

cht-1

23 X

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C04F6.4

C04F6.4a

unc-78

23 X

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The unc-78 gene encodes a homolog of actin-interacting protein 1 (AIP1) that regulates the ordered assembly of actin and cofilin in myofibrils. [Source: WormBase]

C05A9.1

C05A9.1a

pgp-5

23 X

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pgp-5 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily. by homology, PGP-5 is predicted to function as an ATP-dependent efflux pump that protects C. elegans by exporting exogenous toxins. however, as loss of pgp-5 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of PGP-5 in C. elegans development and/or behavior is not yet known. [Source: WormBase]

C05A9.1

C05A9.1b

pgp-5

23 X

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C05A9.2

23 X

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C05C9.1

23 X

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C05C9.3

23 X

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The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77). [Source: WormBase]

C05E11.3

23 X

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C05E11.4

amt-1

23 X

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amt-1 encodes a transmembrane transporter that by homology, is predicted to transport ammonium ions across the plasma membrane. as loss of amt-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of AMT-1 in C. elegans development and/or behavior is not yet known. [Source: WormBase]

C05E11.5

amt-4

23 X

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amt-4 encodes a member of the ammonium transporter protein family. [Source: WormBase]

C05E11.7

23 X

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C05G5.2

23 X

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C06G1.1

C06G1.1a

C06G1.1

23 X

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C06G1.1

C06G1.1b

C06G1.1

23 X

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C06G1.5

23 X

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C07A12.1

C07A12.1a

ham-2

23 X

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The ham-2 gene encodes a C2H2 zinc finger-containing protein required for proper migration of the hermaphrodite-specific neurons (HSNs) and proper attachment of the pharynx to the nose. HAM-2 is expressed in the nuclei of the HSNs during migration, and acts downstream of EGL-5, a posterior group Hox protein, in HSN specification. HAM-2 acts redundantly with UNC-86 to downregulate UNC-43 expression in the HSNs after migration is complete. [Source: WormBase]

C07A12.1

C07A12.1b

ham-2

23 X

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C07A12.1

C07A12.1c

ham-2

23 X

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C07A4.1

tiar-3

23 X

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C07B5.5

nuc-1

23 X

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The nuc-1 gene encodes a DNase II homolog similar to mammalian and Drosophila DNaseII enzymes and is required for DNA degradation during apoptosis as well as for degradation of dietary DNA during normal feeding. during apoptosis, NUC-1 functions in apoptotic cells at an intermediate stage of DNA degradation, after the killing step, but prior to cell-corpse engulfment. [Source: WormBase]

C08A9.9

C08A9.9.1

C08A9.9

23 X

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C08A9.9

C08A9.9.2

C08A9.9

23 X

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C09B8.1

ipp-5

23 X

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ipp-5 encodes a type I inositol 5-phosphatase homolog. ipp-5 acts downstream of let-23 to negatively regulate IP3 signaling and is involved in spermathecal contractions during ovulation. an ipp-5::gfp transcriptional reporter is expressed in the adult distal spermatheca and weakly in the proximal sheath. [Source: WormBase]

C09B8.5

23 X

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C09G1.2

23 X

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C10A4.1

23 X

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C10A4.9

23 X

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C10E2.3

hda-4

23 X

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hda-4 encodes a class II histone deacetylase that contains a putative MEF-2 DNA binding domain, a nuclear localization signal domain, and a single catalytic domain and may affect locomotion, body morphology, and growth. interacts with MEF-2 in in vitro assays and is expressed in body-wall muscle, neurons, and hypodermal seam cells [Source: WormBase]

C10E2.6

C10E2.6.1

C10E2.6

23 X

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C10E2.6

C10E2.6.2

C10E2.6

23 X

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C11E4.6

C11E4.6.1

C11E4.6

23 X

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C11E4.6

C11E4.6.2

C11E4.6

23 X

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C11G6.3

23 X

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C11G6.3 encodes a plant homeodomain-containing protein that is related to the ING (Inhibitor of Growth) family of proteins that function in regulation of gene expression and are candidate tumor suppressors. [Source: WormBase]

C11G6.4

C11G6.4a

nhr-28

23 X

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C11H1.3

23 X

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C11H1.4

C11H1.4a

prx-1

23 X

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prx-1 encodes a predicted peroxin, a subfamily 2 member of the AAA (ATPases Associated with diverse cellular Activities) family that affects growth in one large-scale RNAi screen. expressed in intestinal cells throughout development. [Source: WormBase]

C12D12.2

C12D12.2a.1

glt-1

23 X

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glt-1 encodes a predicted plasma membrane glutamate transporter that is functional when expressed in Xenopus oocytes. expressed in the M3 pharyngeal neuron, the male tail, some anterior hypodermal cells, and in cells in the terminal bulb of the pharynx. [Source: WormBase]

C12D12.2

C12D12.2a.2

glt-1

23 X

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C12D12.5

sox-4

23 X

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C13E3.1

23 X

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C14A11.3

C14A11.3a

cgef-1

23 X

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C14A11.3

C14A11.3b

cgef-1

23 X

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C14A11.3

C14A11.3c

cgef-1

23 X

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C14F11.6

C14F11.6.1

C14F11.6

23 X

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C14F11.6

C14F11.6.2

C14F11.6

23 X

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C15A7.2

23 X

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C15B12.2

C15B12.2.1

C15B12.2

23 X

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C15B12.2

C15B12.2.2

C15B12.2

23 X

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C15B12.4

23 X

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C15B12.7

C15B12.7b

cdf-1

23 X

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a cation diffusion facilitator protein, affects vulva development, genetically interacts with let-60/ras signaling pathway. and is expressed in the vulval muscles, the intestinal cells, and in the vulval precursor cells. [Source: WormBase]

C15C7.2

C15C7.2.1

klp-8

23 X

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klp-8 encodes an atypical kinesin-like motor protein with the motor domain in the N-terminus. the motor domain of KLP-8 exhibits poor homology to the globular motor domain of the kinesin heavy chain. [Source: WormBase]

C15C7.2

C15C7.2.2

klp-8

23 X

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C15H9.1

nnt-1

23 X

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nnt-1 encodes a proton-pumping nicotinamide nucleotide transhydrogenase predicted to be mitochondrial. [Source: WormBase]

C15H9.5

C15H9.5.1

C15H9.5

23 X

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C15H9.5

C15H9.5.2

C15H9.5

23 X

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C15H9.6

C15H9.6.1

hsp-3

23 X

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hsp-3 encodes one of two C. elegans heat shock response 70 (hsp70) proteins homologous to mammalian grp78/BiP (glucose regulated protein 78/immunoglobulin heavy chain-binding protein, OMIM:138120). HSP-3 likely functions as a molecular chaperone, and is expressed constitutively (expression is not heat inducible) throughout development with greatest abundance during the L1 larval stage. hsp-3 transcription is, however, upregulated in response to endoplasmic reticulum stress induced by dithiothreitol (DTT) or tunicamycin. HSP-3 contains a long hydrophobic amino terminus and a carboxyl terminal KDEL sequence suggesting that it may be retained in the endoplasmic reticulum. [Source: WormBase]

C15H9.6

C15H9.6.2

hsp-3

23 X

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C15H9.6

C15H9.6.3

hsp-3

23 X

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