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Genome: Caenorhabditis Elegans | mRNA | miRBase 18 (Nov. 2011), ENSEMBL 65 (Dec. 2011) and RNA22v1.0
Description: List of transcripts that are targeted by all of the below miRNA identifiers simultaneously
miRNA's: cel-miR-1018 (MIMAT0005031)
Filtering By: Base pair min value: 12 | Folding energy max value (Kcal/mol): -21 | Min miRNA targets: 1


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Gene IDTranscript IDCommon Gene Name# of miRNA targets
for specified miRNAs
ChromosomeStrand DirectionTranscript Link to view miRNA target predictionsGene LinkDescription
6R55.26R55.26R55.2123 XForwardView as cDNA map |
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Ensembl
AH9.1AH9.1AH9.1123 XReverseView as cDNA map |
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Ensembl
AH9.2AH9.2crn-4123 XReverseView as cDNA map |
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Ensembl
AH9.4AH9.4AH9.4123 XReverseView as cDNA map |
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Ensembl
AH9.6AH9.6AH9.6223 XReverseView as cDNA map |
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Ensembl
AH9.6 encodes a novel protein that contains two predicted transmembrane domains and that is conserved in other nematode species. [Source: WormBase]
B0198.2B0198.2aB0198.2123 XForwardView as cDNA map |
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Ensembl
B0272.1B0272.1tbb-4323 XReverseView as cDNA map |
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Ensembl
B0272.2B0272.2memb-1123 XReverseView as cDNA map |
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Ensembl
B0272.4B0272.4B0272.4123 XForwardView as cDNA map |
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Ensembl
B0302.1B0302.1a.1kin-25223 XForwardView as cDNA map |
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Ensembl
kin-25 encodes a nonreceptor tyrosine kinase that is a member of the Ack subfamily of cytoplasmic tyrosine kinases. [Source: WormBase]
B0302.1B0302.1a.2kin-25123 XForwardView as cDNA map |
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Ensembl
kin-25 encodes a nonreceptor tyrosine kinase that is a member of the Ack subfamily of cytoplasmic tyrosine kinases. [Source: WormBase]
B0310.5B0310.5ugt-46123 XReverseView as cDNA map |
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Ensembl
B0395.2B0395.2mboa-1323 XForwardView as cDNA map |
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Ensembl
mboa-1 encodes a putative acyl-Coenzyme A:cholesterol ('sterol') O-acyltransferase, orthologous to human SOAT1 (OMIM:102642). MBOA-1 is required for normal locomotion and normally long lifespan in mass RNAi assays. mboa-1 is expressed in the seam cells and nervous systems of larvae and adults, and in the adult reproductive system. [Source: WormBase]
B0403.2B0403.2ubc-17123 XForwardView as cDNA map |
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Ensembl
B0403.4B0403.4tag-320123 XReverseView as cDNA map |
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Ensembl
B0403.6B0403.6B0403.6123 XReverseView as cDNA map |
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Ensembl
B0410.1B0410.1B0410.1123 XForwardView as cDNA map |
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Ensembl
B0410.2B0410.2avang-1123 XForwardView as cDNA map |
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Ensembl
vang-1 encodes an ortholog of Drosophila VAN GOGH (also known as STRABISMUS). VANG-1 enables Wnt-directed planar cell polarity. VANG-1 is required for the fully asymmetrical division of B.a versus B.p cells, though this requirement is quantitatively weak. [Source: WormBase]
B0410.2B0410.2bvang-1123 XForwardView as cDNA map |
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Ensembl
vang-1 encodes an ortholog of Drosophila VAN GOGH (also known as STRABISMUS). VANG-1 enables Wnt-directed planar cell polarity. VANG-1 is required for the fully asymmetrical division of B.a versus B.p cells, though this requirement is quantitatively weak. [Source: WormBase]
B0416.1B0416.1B0416.1423 XForwardView as cDNA map |
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Ensembl
B0416.2B0416.2B0416.2223 XForwardView as cDNA map |
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Ensembl
B0416.3B0416.3B0416.3223 XForwardView as cDNA map |
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Ensembl
B0416.6B0416.6gly-13223 XReverseView as cDNA map |
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Ensembl
gly-13 encodes an experimentally verified UDP-N-acetylglucosamine alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I (GnT I), that is the primary GnT I enzyme in vivo, and that can act on unusual substrates. gly-13 is expressed throughout development in many cell types. gly-13 has no obvious function in vivo, since a deletion allele of gly-13 is phenotypically normal even as a double or triple mutant with gly-12 and gly-14. [Source: WormBase]
B0563.4B0563.4.1tmbi-4223 XForwardView as cDNA map |
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Ensembl
B0563.4B0563.4.2tmbi-4223 XForwardView as cDNA map |
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Ensembl
B0563.7B0563.7B0563.7123 XReverseView as cDNA map |
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Ensembl
C01C10.3C01C10.3.1acl-12123 XReverseView as cDNA map |
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Ensembl
C01C10.3C01C10.3.2acl-12123 XReverseView as cDNA map |
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Ensembl
C01C10.4C01C10.4clc-5123 XForwardView as cDNA map |
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Ensembl
clc-5 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia. CLC-5 is worm-specific, with obvious homologs only in C. elegans. CLC-5 has no obvious function in mass RNAi assays. claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water. [Source: WormBase]
C01C4.2C01C4.2C01C4.2123 XForwardView as cDNA map |
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Ensembl
C01C4.3C01C4.3bC01C4.3323 XForwardView as cDNA map |
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Ensembl
C01C4.3 encodes a serine/threonine protein kinase. [Source: WormBase]
C02B4.1C02B4.1adt-1223 XForwardView as cDNA map |
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Ensembl
The adt-1 gene encodes a metalloproteinase with disintegrin-like and metalloproteinase with thrombospondin type I motifs (ADAMTS) that is required for male tail morphogenesis. [Source: WormBase]
C02B8.5C02B8.5C02B8.5123 XReverseView as cDNA map |
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C02B8.5 encodes a homolog of the functionally active Fmrf Receptor (FR. CG2114) of D. melanogaster. it is thus possible that C02B8.5 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12). [Source: WormBase]
C02B8.6C02B8.6C02B8.6123 XReverseView as cDNA map |
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Ensembl
C02C6.1C02C6.1adyn-1323 XForwardView as cDNA map |
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Ensembl
dyn-1 encodes the C. elegans ortholog of the dynamin GTPase. dyn-1 activity is required for endocytosis, synaptic vesicle recycling, cytokinesis, and the CED-1 pathway that regulates engulfment and degradation of apoptotic cells. mutations in dyn-1 affect locomotion, egg-laying, defecation, and embryonic development, indicating that dyn-1's endocytic function is required for a number of diverse processes. dyn-1 reporter fusion constructs are expressed in motor neurons, intestinal cells, and pharyngeal muscle. [Source: WormBase]
C02C6.1C02C6.1bdyn-1423 XForwardView as cDNA map |
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dyn-1 encodes the C. elegans ortholog of the dynamin GTPase. dyn-1 activity is required for endocytosis, synaptic vesicle recycling, cytokinesis, and the CED-1 pathway that regulates engulfment and degradation of apoptotic cells. mutations in dyn-1 affect locomotion, egg-laying, defecation, and embryonic development, indicating that dyn-1's endocytic function is required for a number of diverse processes. dyn-1 reporter fusion constructs are expressed in motor neurons, intestinal cells, and pharyngeal muscle. [Source: WormBase]
C02C6.2C02C6.2aolrn-1223 XForwardView as cDNA map |
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olrn-1 encodes, by alternative splicing, two isoforms of a transmembrane protein required for differentiation of the AWC[ON] neuron, expression of str-2 in AWC[ON], adaptation to benzaldehyde, chemotaxis to butanone, and enhancement of chemotaxis to butanone by the presence of food. OLRN-1 is orthologous to Drosophila melanogaster RAW and Schistosoma japonicum SJCHGC05616. while OLRN-1 has orthologs in nematodes, trematodes, and arthropods, its has no obvious chordate homologs. OLRN-6 is expressed in many pharyngeal neurons and some head neurons, but is required solely in the AWC[ON] neuron for butanone enhancement. OLRN-6's function in butanone enhancement is both serotonin- and dopamine-independent, and appears to also act in chemotactic enhancement of 2,3-pentanedione and isoamyl alcohol. by orthology with RAW, OLRN-6 is predicted to inhibit JNK-1 signalling, which may in turn allow the asymmetrical AWC[ON] fate to emerge. [Source: WormBase]
C02C6.2C02C6.2bolrn-1123 XForwardView as cDNA map |
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olrn-1 encodes, by alternative splicing, two isoforms of a transmembrane protein required for differentiation of the AWC[ON] neuron, expression of str-2 in AWC[ON], adaptation to benzaldehyde, chemotaxis to butanone, and enhancement of chemotaxis to butanone by the presence of food. OLRN-1 is orthologous to Drosophila melanogaster RAW and Schistosoma japonicum SJCHGC05616. while OLRN-1 has orthologs in nematodes, trematodes, and arthropods, its has no obvious chordate homologs. OLRN-6 is expressed in many pharyngeal neurons and some head neurons, but is required solely in the AWC[ON] neuron for butanone enhancement. OLRN-6's function in butanone enhancement is both serotonin- and dopamine-independent, and appears to also act in chemotactic enhancement of 2,3-pentanedione and isoamyl alcohol. by orthology with RAW, OLRN-6 is predicted to inhibit JNK-1 signalling, which may in turn allow the asymmetrical AWC[ON] fate to emerge. [Source: WormBase]
C02C6.3C02C6.3aC02C6.3123 XReverseView as cDNA map |
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Ensembl
C02C6.3C02C6.3d.1C02C6.3223 XReverseView as cDNA map |
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Ensembl
C02C6.3C02C6.3d.2C02C6.3223 XReverseView as cDNA map |
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Ensembl
C02D4.2C02D4.2aser-2123 XReverseView as cDNA map |
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Ensembl
ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase]
C02D4.2C02D4.2bser-2123 XReverseView as cDNA map |
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Ensembl
ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase]
C02D4.2C02D4.2eser-2123 XReverseView as cDNA map |
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Ensembl
ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase]
C02D4.2C02D4.2fser-2123 XReverseView as cDNA map |
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Ensembl
ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase]
C02F12.3C02F12.3.1C02F12.3123 XReverseView as cDNA map |
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C02F12.3C02F12.3.2C02F12.3123 XReverseView as cDNA map |
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C02F12.4C02F12.4tag-52123 XReverseView as cDNA map |
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Ensembl
C02F12.5C02F12.5C02F12.5123 XReverseView as cDNA map |
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C02F12.5 encodes a putatively secreted protein with a Kunitz/bovine pancreatic trypsin inhibitor domain. C02F12.5 has no obvious function in mass RNAi assays. [Source: WormBase]
C02F12.7C02F12.7tag-278123 XReverseView as cDNA map |
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Ensembl
C02F12.8C02F12.8C02F12.8223 XReverseView as cDNA map |
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C02H7.2C02H7.2npr-19423 XReverseView as cDNA map |
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Ensembl
C02H7.3C02H7.3aaex-3323 XReverseView as cDNA map |
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aex-3 encodes a guanine nucleotide exchange factor for the rab-3 GTPase that is orthologous to human MAP kinase activating protein containing death domain (MADD, OMIM:603584). AEX-3 is required for intracellular vesicle trafficking as well as synaptic vesicle release and interacts with CAB-1 and RAB-3 to regulate separate pathways for neural activities such as defecation and male mating, respectively. AEX-3 is also required for egg laying and locomotion. AEX-3 is expressed in nearly all neurons. [Source: WormBase]
C03A3.2C03A3.2.1C03A3.2123 XForwardView as cDNA map |
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C03A3.2C03A3.2.2C03A3.2123 XForwardView as cDNA map |
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C03B1.13C03B1.13C03B1.13223 XReverseView as cDNA map |
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C03B1.2C03B1.2C03B1.2123 XForwardView as cDNA map |
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C03B1.4C03B1.4C03B1.4123 XForwardView as cDNA map |
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C03B1.7C03B1.7C03B1.7223 XForwardView as cDNA map |
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C03F11.1C03F11.1C03F11.1223 XForwardView as cDNA map |
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C03F11.3C03F11.3scav-1123 XReverseView as cDNA map |
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C03G5.7C03G5.7flp-5123 XForwardView as cDNA map |
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flp-5 encodes a predicted FMRFamide-like peptide neurotransmitter that increases action potential frequency in the pharyngeal muscle when applied to the pharynx of dissected worms. expressed in the sensory neurons ASE and PVM. [Source: WormBase]
C03H12.1C03H12.1C03H12.1123 XForwardView as cDNA map |
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C04A11.1C04A11.1C04A11.1223 XForwardView as cDNA map |
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C04A11.4C04A11.4adm-2223 XForwardView as cDNA map |
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adm-2 encodes a protein containing a snake venom disintegrin-domain and a metalloprotease-like domain (i.e., a protein of the ADAM family). like ADM-1, ADM-2 is homologous to a mammalian sperm glycoprotein (PH-30/fertilin) implicated in sperm-egg fusion, and ADM-2 might thus be a fusogenic protein mediating the merging of plasma membranes during development. [Source: WormBase]
C04B4.1C04B4.1.1C04B4.1323 XForwardView as cDNA map |
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C04B4.1C04B4.1.2C04B4.1323 XForwardView as cDNA map |
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C04B4.2C04B4.2C04B4.2123 XForwardView as cDNA map |
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C04B4.4C04B4.4C04B4.4123 XForwardView as cDNA map |
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C04E7.2C04E7.2sor-3223 XForwardView as cDNA map |
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sor-3 encodes a novel protein that contains an MBT (malignant brain tumor) domain related to the MBT domains found in the Sex comb on midleg (SCM) and Sfmbt Polycomb group proteins. during development, SOR-3 activity is required to specify the correct number of dopaminergic and serotonergic neurons in males, as well as for proper ray neuron axon guidance, distal tip cell migration, and normal body size. SOR-3 activity is necessary for maintaining repression of Hox gene expression, notably that of egl-5 in many head neurons. in regulating neurotransmitter phenotype, sor-3 functions together with sop-2, which also encodes a Polycomb group protein, and members of the TGF-beta signaling pathway. sor-3 and sop-2 also function together to regulate progression through larval development. a SOR-3::GFP reporter fusion is expressed ubiquitously throughout the life cycle and localizes to both the cytoplasm and the nucleus. [Source: WormBase]
C04E7.4C04E7.4C04E7.4323 XReverseView as cDNA map |
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C04F6.1C04F6.1vit-5523 XForwardView as cDNA map |
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vit-5 encodes a vitellogenin, a lipid-binding protein precursor related to vertebrate vitellogenins and mammalian ApoB-100, a core LDL particle constituent. by homology, VIT-5 is predicted to function as a lipid transport protein. loss of vit-5 activity via large-scale RNA-mediated interference (RNAi) screens indicates that VIT-5 is required for embryogenesis and normal rates of postembryonic growth. VIT-5 is a major yolk component and is expressed exclusively in the adult hermaphrodite intestine from which it is secreted into the pseudocoelomic space and taken up by oocytes. [Source: WormBase]
C04F6.4C04F6.4aunc-78323 XReverseView as cDNA map |
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The unc-78 gene encodes a homolog of actin-interacting protein 1 (AIP1) that regulates the ordered assembly of actin and cofilin in myofibrils. [Source: WormBase]
C05C9.1C05C9.1C05C9.1223 XForwardView as cDNA map |
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C05C9.3C05C9.3C05C9.3223 XReverseView as cDNA map |
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The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77). [Source: WormBase]
C05D9.3C05D9.3C05D9.3123 XForwardView as cDNA map |
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C05E11.1C05E11.1.1lnp-1123 XForwardView as cDNA map |
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lnp-1 encodes a highly conserved protein of unknown function, orthologous to human LUNAPARK/KIAA1715 (OMIM:610236), that is required for normally short body length, normal locomotion, fat content, acetylcholine neurotransmission, localization of RAB-3 and SNB-1, and sensitivity to aldicarb. LNP-1 is expressed in muscles, hypodermal cells, and neurons. within neurons, LNP-1 is localized to cell bodies, neuritic processes and commissures, and requiring UNC-104 for localization outside of cell bodies. LNP-1 is likely to act presynaptically. LNP-1 contains two N-terminal predicted transmembrane sequences, and an atypical zinc finger domain (C2HC2). [Source: WormBase]
C05E11.4C05E11.4amt-1123 XForwardView as cDNA map |
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amt-1 encodes a transmembrane transporter that by homology, is predicted to transport ammonium ions across the plasma membrane. as loss of amt-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of AMT-1 in C. elegans development and/or behavior is not yet known. [Source: WormBase]
C05E11.5C05E11.5amt-4123 XForwardView as cDNA map |
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amt-4 encodes a member of the ammonium transporter protein family. [Source: WormBase]
C05E7.1C05E7.1C05E7.1123 XReverseView as cDNA map |
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C05E7.2C05E7.2C05E7.2123 XReverseView as cDNA map |
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C05E7.3C05E7.3C05E7.3123 XReverseView as cDNA map |
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C05E7.4C05E7.4C05E7.4123 XForwardView as cDNA map |
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C05G5.1C05G5.1C05G5.1123 XReverseView as cDNA map |
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C05G5.2C05G5.2C05G5.2223 XForwardView as cDNA map |
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C06E2.5C06E2.5.1C06E2.5123 XReverseView as cDNA map |
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C06E2.5C06E2.5.2C06E2.5123 XReverseView as cDNA map |
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C06G1.1C06G1.1aC06G1.1223 XForwardView as cDNA map |
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C06G1.1C06G1.1bC06G1.1323 XForwardView as cDNA map |
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C06G1.4C06G1.4.1ain-1423 XForwardView as cDNA map |
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ain-1 encodes an unfamiliar protein synergistically required, with LIN-31, for the normal timing of vulval differentiation, independently of LET-60/RAS, and parallel to or downstream of LIN-14/LIN-28/HBL-1. AIN-1 is expressed in cytoplasmic foci (that are probably P bodies) in several tissues, including vulval precursor cells and neurons. AIN-1 coimmunoprecipitates with DCR-1 and ALG-1, also binds ALG-1 in vitro, and does not require DNA or RNA for its binding. in vivo, AIN-1 targets ALG-1 to cytoplasmic foci, in which it colocalizes with DCAP-2. AIN-1 is likely to be a RISC component, since anti-AIN-1 antibodies precipitate 29 different miRNAs, including mir-2, mir-52, mir-58, mir-71, mir-77, and mir-239a. ain-1(ku322) mutants are essentially wild-type, except for sporadically gapped alae and excess seam cell nuclei arising from retarded seam cell fusion. more prominently, ain-1(ku322) suppresses the multivulva phenotype of lin-31(n1053) mutations, while strongly enhancing lin-31(n1053)'s egg-laying defect. the cellular basis of lin-31(n1053).ain-1(ku322) phenotypes is a delay in vulval development in L4 larvae not seen with either mutation alone. ain-1(ku322) has no effect on let-60(n1046) or lin-3(e1275) mutations. ain-1(ku322) suppresses the precocious vulval development of lin-14(RNAi), lin-28 mutants, and hbl-1(RNAi). alg-1 or alg-1 ain-1 mutant alae resemble ain-1 alae, indicating that ALG-1 and AIN-1 act in a common genetic pathway. AIN-1 is homologous to Brugia malayi 14748.m00068, 14052.m00191, and 14963.m01790, and paralogous to C. elegans B0041.2. AIN-1 and its nematode homologs have weak similarity to human TNRC6A (GW182. OMIM:610739) and Drosophila GAWKY. [Source: WormBase]
C07A12.1C07A12.1aham-2123 XForwardView as cDNA map |
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The ham-2 gene encodes a C2H2 zinc finger-containing protein required for proper migration of the hermaphrodite-specific neurons (HSNs) and proper attachment of the pharynx to the nose. HAM-2 is expressed in the nuclei of the HSNs during migration, and acts downstream of EGL-5, a posterior group Hox protein, in HSN specification. HAM-2 acts redundantly with UNC-86 to downregulate UNC-43 expression in the HSNs after migration is complete. [Source: WormBase]
C07A12.1C07A12.1bham-2123 XForwardView as cDNA map |
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The ham-2 gene encodes a C2H2 zinc finger-containing protein required for proper migration of the hermaphrodite-specific neurons (HSNs) and proper attachment of the pharynx to the nose. HAM-2 is expressed in the nuclei of the HSNs during migration, and acts downstream of EGL-5, a posterior group Hox protein, in HSN specification. HAM-2 acts redundantly with UNC-86 to downregulate UNC-43 expression in the HSNs after migration is complete. [Source: WormBase]
C07A12.1C07A12.1cham-2123 XForwardView as cDNA map |
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The ham-2 gene encodes a C2H2 zinc finger-containing protein required for proper migration of the hermaphrodite-specific neurons (HSNs) and proper attachment of the pharynx to the nose. HAM-2 is expressed in the nuclei of the HSNs during migration, and acts downstream of EGL-5, a posterior group Hox protein, in HSN specification. HAM-2 acts redundantly with UNC-86 to downregulate UNC-43 expression in the HSNs after migration is complete. [Source: WormBase]
C07A12.3C07A12.3anhr-35123 XForwardView as cDNA map |
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C07A12.4C07A12.4a.1pdi-2223 XForwardView as cDNA map |
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C07A12.4C07A12.4a.2pdi-2223 XForwardView as cDNA map |
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C07A12.4C07A12.4bpdi-2223 XForwardView as cDNA map |
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Ensembl
C07A12.4C07A12.4cpdi-2123 XForwardView as cDNA map |
View as Table
Internal |
Ensembl
C07A12.5C07A12.5aspr-3223 XForwardView as cDNA map |
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Internal |
Ensembl
C07A12.7C07A12.7a.1C07A12.7123 XReverseView as cDNA map |
View as Table
Internal |
Ensembl
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GUI created by the Computational Medicine Center at the Sidney Kimmel Medical College of Thomas Jefferson University
We gratefully acknowledge support of this work by the William M. Keck Foundation