| Gene ID | Transcript ID | Common Gene Name | # of miRNA targets for specified miRNAs | Chromosome | Strand Direction | Transcript Link to view miRNA target predictions | Gene Link | Description |
|---|---|---|---|---|---|---|---|---|
| AH9.6 | AH9.6 | AH9.6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | AH9.6 encodes a novel protein that contains two predicted transmembrane domains and that is conserved in other nematode species. [Source: WormBase] |
| B0272.1 | B0272.1 | tbb-4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| B0302.1 | B0302.1a.1 | kin-25 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | kin-25 encodes a nonreceptor tyrosine kinase that is a member of the Ack subfamily of cytoplasmic tyrosine kinases. [Source: WormBase] |
| B0310.2 | B0310.2.1 | B0310.2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| B0310.2 | B0310.2.2 | B0310.2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| B0416.1 | B0416.1 | B0416.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0416.4 | B0416.4 | B0416.4 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0563.10 | B0563.10 | B0563.10 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C02B4.2 | C02B4.2 | nhr-17 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | nhr-17 encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators. nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain. [Source: WormBase] |
| C03F11.4 | C03F11.4.1 | C03F11.4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C03F11.4 | C03F11.4.2 | C03F11.4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C03F11.4 | C03F11.4.3 | C03F11.4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C04A11.3 | C04A11.3 | gck-4 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C05E7.2 | C05E7.2 | C05E7.2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C06G1.4 | C06G1.4.1 | ain-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | ain-1 encodes an unfamiliar protein synergistically required, with LIN-31, for the normal timing of vulval differentiation, independently of LET-60/RAS, and parallel to or downstream of LIN-14/LIN-28/HBL-1. AIN-1 is expressed in cytoplasmic foci (that are probably P bodies) in several tissues, including vulval precursor cells and neurons. AIN-1 coimmunoprecipitates with DCR-1 and ALG-1, also binds ALG-1 in vitro, and does not require DNA or RNA for its binding. in vivo, AIN-1 targets ALG-1 to cytoplasmic foci, in which it colocalizes with DCAP-2. AIN-1 is likely to be a RISC component, since anti-AIN-1 antibodies precipitate 29 different miRNAs, including mir-2, mir-52, mir-58, mir-71, mir-77, and mir-239a. ain-1(ku322) mutants are essentially wild-type, except for sporadically gapped alae and excess seam cell nuclei arising from retarded seam cell fusion. more prominently, ain-1(ku322) suppresses the multivulva phenotype of lin-31(n1053) mutations, while strongly enhancing lin-31(n1053)'s egg-laying defect. the cellular basis of lin-31(n1053).ain-1(ku322) phenotypes is a delay in vulval development in L4 larvae not seen with either mutation alone. ain-1(ku322) has no effect on let-60(n1046) or lin-3(e1275) mutations. ain-1(ku322) suppresses the precocious vulval development of lin-14(RNAi), lin-28 mutants, and hbl-1(RNAi). alg-1 or alg-1 ain-1 mutant alae resemble ain-1 alae, indicating that ALG-1 and AIN-1 act in a common genetic pathway. AIN-1 is homologous to Brugia malayi 14748.m00068, 14052.m00191, and 14963.m01790, and paralogous to C. elegans B0041.2. AIN-1 and its nematode homologs have weak similarity to human TNRC6A (GW182. OMIM:610739) and Drosophila GAWKY. [Source: WormBase] |
| C10A4.2 | C10A4.2 | C10A4.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C10A4.5 | C10A4.5 | C10A4.5 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C11E4.3 | C11E4.3 | tag-263 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C11E4.6 | C11E4.6.1 | C11E4.6 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C11E4.6 | C11E4.6.2 | C11E4.6 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C12D12.1 | C12D12.1c | C12D12.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C14E2.4 | C14E2.4 | C14E2.4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C14F11.7 | C14F11.7 | C14F11.7 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C14F5.3 | C14F5.3a | tnt-3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | tnt-3 is orthologous to the human gene TROPONIN T (TNNT2. OMIM:191045), which when mutated leads to disease. [Source: WormBase] |
| C14F5.3 | C14F5.3c.1 | tnt-3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | tnt-3 is orthologous to the human gene TROPONIN T (TNNT2. OMIM:191045), which when mutated leads to disease. [Source: WormBase] |
| C14F5.3 | C14F5.3c.2 | tnt-3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | tnt-3 is orthologous to the human gene TROPONIN T (TNNT2. OMIM:191045), which when mutated leads to disease. [Source: WormBase] |
| C14F5.3 | C14F5.3d | tnt-3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | tnt-3 is orthologous to the human gene TROPONIN T (TNNT2. OMIM:191045), which when mutated leads to disease. [Source: WormBase] |
| C15A7.2 | C15A7.2 | C15A7.2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C15H9.2 | C15H9.2 | C15H9.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C17G1.1 | C17G1.1 | C17G1.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C17G1.7 | C17G1.7.1 | C17G1.7 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C17H11.6 | C17H11.6a | C17H11.6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C17H11.6 | C17H11.6b | C17H11.6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C17H11.6 | C17H11.6c.1 | C17H11.6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C17H11.6 | C17H11.6c.2 | C17H11.6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C17H11.6 | C17H11.6c.3 | C17H11.6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C17H11.6 | C17H11.6d | C17H11.6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C18A11.3 | C18A11.3 | C18A11.3 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C18B12.3 | C18B12.3 | dsc-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C23H4.7 | C23H4.7 | C23H4.7 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C24A8.1 | C24A8.1 | dop-6 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | dop-6 encodes an homolog of mammalian D2 or D3 dopamine receptors, and a paralog of DOP-2/-3. dop-6 is expressed in the nervous system. because of its paralogy, DOP-6 might act redundantly with DOP-2 to promote the basal slowing response to bacterial feeding, or it might account for the residual response to excess dopamine seen in triple dop-1/-2/-3 mutants. but dop-6 otherwise has no obvious function in RNAi assays of brood size, egg laying, pharyngeal pumping, locomotion, or male mating. [Source: WormBase] |
| C25B8.5 | C25B8.5 | C25B8.5 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C25F6.2 | C25F6.2a.1 | dlg-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | dlg-1 encodes a MAGUK protein, orthologous to Drosophila disks large, that is physically located to adherens junctions in all epithelia and that is genetically required for organization of the embryonic gut epithelium into an coherent tube. [Source: WormBase] |
| C25F6.2 | C25F6.2a.2 | dlg-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | dlg-1 encodes a MAGUK protein, orthologous to Drosophila disks large, that is physically located to adherens junctions in all epithelia and that is genetically required for organization of the embryonic gut epithelium into an coherent tube. [Source: WormBase] |
| C25F6.2 | C25F6.2b.1 | dlg-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | dlg-1 encodes a MAGUK protein, orthologous to Drosophila disks large, that is physically located to adherens junctions in all epithelia and that is genetically required for organization of the embryonic gut epithelium into an coherent tube. [Source: WormBase] |
| C25F6.2 | C25F6.2b.2 | dlg-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | dlg-1 encodes a MAGUK protein, orthologous to Drosophila disks large, that is physically located to adherens junctions in all epithelia and that is genetically required for organization of the embryonic gut epithelium into an coherent tube. [Source: WormBase] |
| C25F6.2 | C25F6.2b.3 | dlg-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | dlg-1 encodes a MAGUK protein, orthologous to Drosophila disks large, that is physically located to adherens junctions in all epithelia and that is genetically required for organization of the embryonic gut epithelium into an coherent tube. [Source: WormBase] |
| C25F6.7 | C25F6.7a | C25F6.7 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C26B9.1 | C26B9.1a | C26B9.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C26B9.2 | C26B9.2 | C26B9.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C33A11.4 | C33A11.4b | tag-97 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C34E7.4 | C34E7.4 | C34E7.4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C34F6.4 | C34F6.4 | hst-2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | hst-2 encodes the C. elegans ortholog of the heparan sulfate modifying enzyme 2O-sulfotransferase. by homology, HST-2 is predicted to function in heparan sulfate biosynthesis by catalyzing the chain-modifying sulfation of the C2 hydroxyl group of hexuronic acid. during development, hst-2 activity is required for normal body size, cell migration, and nervous system development. an hst-2::gfp reporter fusion is first expressed in embryos, continuing on through adulthood. expression is detected in many tissues, including the pharynx, hypodermis, muscles, vulva, and distal tip cells (DTCs) of the somatic gonad. [Source: WormBase] |
| C35C5.1 | C35C5.1 | sdc-2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | The sdc-2 gene encodes a protein that represses transcription of X chromosomes to achieve dosage compensation, and that also represses the male sex-determination gene her-1 to elicit hermaphrodite differentiation. [Source: WormBase] |
| C35C5.6 | C35C5.6 | C35C5.6 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C36B7.2 | C36B7.2 | C36B7.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C38C5.1 | C38C5.1a | C38C5.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C39B10.2 | C39B10.2a | lgc-41 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C39B10.2 | C39B10.2b | lgc-41 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C39E6.1 | C39E6.1.1 | lon-2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | lon-2 encodes a member of the glypican family of heparan sulfate proteoglycans. during development, lon-2 activity is required in the hypodermis for negative regulation of the DBL-1/BMP signaling pathway that regulates body length. genetic analyses indicate that lon-2 functions upstream of dbl-1, and in vitro studies show that LON-2 can bind mammalian BMP2, suggesting that LON-2 may directly interact with DBL-1 to negatively regulate DBL-1/BMP signaling. in addition to expression in hypodermis, LON-2 is expressed strongly in the intestine, particularly the anterior and posterior cells. LON-2 localizes to the cell surface. [Source: WormBase] |
| C39E6.1 | C39E6.1.2 | lon-2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | lon-2 encodes a member of the glypican family of heparan sulfate proteoglycans. during development, lon-2 activity is required in the hypodermis for negative regulation of the DBL-1/BMP signaling pathway that regulates body length. genetic analyses indicate that lon-2 functions upstream of dbl-1, and in vitro studies show that LON-2 can bind mammalian BMP2, suggesting that LON-2 may directly interact with DBL-1 to negatively regulate DBL-1/BMP signaling. in addition to expression in hypodermis, LON-2 is expressed strongly in the intestine, particularly the anterior and posterior cells. LON-2 localizes to the cell surface. [Source: WormBase] |
| C39E6.1 | C39E6.1.3 | lon-2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | lon-2 encodes a member of the glypican family of heparan sulfate proteoglycans. during development, lon-2 activity is required in the hypodermis for negative regulation of the DBL-1/BMP signaling pathway that regulates body length. genetic analyses indicate that lon-2 functions upstream of dbl-1, and in vitro studies show that LON-2 can bind mammalian BMP2, suggesting that LON-2 may directly interact with DBL-1 to negatively regulate DBL-1/BMP signaling. in addition to expression in hypodermis, LON-2 is expressed strongly in the intestine, particularly the anterior and posterior cells. LON-2 localizes to the cell surface. [Source: WormBase] |
| C39E6.6 | C39E6.6 | npr-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | npr-1 encodes a predicted G protein-coupled neuropeptide receptor that is homologous to the mammalian neuropeptide Y (NPY) receptor (OMIM:162641) required for regulating anxiety, food consumption, and pain sensation. in C. elegans, NPR-1 is involved in ethological variations of social behavior such as social versus solitary feeding. in regulating social behavior, NPR-1 functions as a receptor for the FLP-18 and FLP-21 peptide ligands. NPR-1 also affects some aspect of UNC-6/netrin-mediated branching of motor neurons, as strong npr-1 mutations can suppress abnormal migration of ventral nerve cord neurons induced by overexpression of UNC-6 lacking domain C. NPR-1 is expressed predominantly in the nervous system, and particularly in the AQR, PQR, and URX neurons that are exposed to the body fluid. [Source: WormBase] |
| C40C9.5 | C40C9.5a | nlg-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | nlg-1 encodes the sole C. elegans neuroligin homolog. nlg-1 activity is required for a subset of sensory behaviors and sensory processing, and for normal sensitivity to oxidative stress and mercury compounds. NLG-1 is expressed in a variety of neurons, including sensory, motor, and interneurons, and localizes to synaptic regions. [Source: WormBase] |
| C40C9.5 | C40C9.5c | nlg-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | nlg-1 encodes the sole C. elegans neuroligin homolog. nlg-1 activity is required for a subset of sensory behaviors and sensory processing, and for normal sensitivity to oxidative stress and mercury compounds. NLG-1 is expressed in a variety of neurons, including sensory, motor, and interneurons, and localizes to synaptic regions. [Source: WormBase] |
| C41G11.3 | C41G11.3 | rgs-6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | rgs-6 encodes a regulator of G protein signaling. by homology, RGS-6 is predicted to function as a GTPase-activating protein that binds G protein alpha subunits and negatively regulates heterotrimeric G protein signaling. loss of rgs-6 activity via RNAi or a deletion mutation results in no obvious defects, and likewise, rgs-6 overexpression has no measurable effect on egg-laying behavior, locomotion, or viability. the rgs-6 expression pattern has not yet been reported. [Source: WormBase] |
| C42D8.2 | C42D8.2a | vit-2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | The vit-2 gene encodes the vitellogenin homolog YP170. [Source: WormBase] |
| C44C1.5 | C44C1.5a | C44C1.5 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C44C10.3 | C44C10.3 | C44C10.3 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C44E12.1 | C44E12.1 | C44E12.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C45B2.2 | C45B2.2 | C45B2.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C45B2.4 | C45B2.4a | ggr-2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | ggr-2 encodes a predicted member of the GABA/ glycine receptor family of ligand-gated chloride channels that affects thermotaxis. expressed in neurons that include SMDV, SMDD, SIAV, CAN, HSN, DD, and is weakly expressed in the egg-laying muscles. [Source: WormBase] |
| C45B2.4 | C45B2.4b.1 | ggr-2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | ggr-2 encodes a predicted member of the GABA/ glycine receptor family of ligand-gated chloride channels that affects thermotaxis. expressed in neurons that include SMDV, SMDD, SIAV, CAN, HSN, DD, and is weakly expressed in the egg-laying muscles. [Source: WormBase] |
| C45B2.4 | C45B2.4b.2 | ggr-2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | ggr-2 encodes a predicted member of the GABA/ glycine receptor family of ligand-gated chloride channels that affects thermotaxis. expressed in neurons that include SMDV, SMDD, SIAV, CAN, HSN, DD, and is weakly expressed in the egg-laying muscles. [Source: WormBase] |
| C46C11.4 | C46C11.4 | C46C11.4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C52B9.6 | C52B9.6 | twk-28 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C53C9.2 | C53C9.2 | C53C9.2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C53C9.3 | C53C9.3a | kvs-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | kvs-1 encodes a voltage-gated, A-type potassium channel. kvs-1 is required for the normal function of several neurons and thus for normal forward locomotion, chemotaxis to select molecules, osmotic avoidance, and nose-touch. when expressed in tissue culture cells, KVS-1 exhibits potassium-selective channel activity that is altered by coexpression with C. elegans MPS-1, -2, -3, and -4, KCNE-like ancillary subunits, or a related human protein, hMiRP1. in addition, KVS-1 forms a functional complex with MPS-1 in the ASER neuron and activity of MPS-2, MPS-3, and KVS-1 coexpressed in culture suggests that these three proteins can form a functional ternary complex that genetic analyses indicate likely plays a role in regulating responsiveness to sodium. kvs-1 reporter fusions are expressed in sperm, the anal depressor muscle, the PDA motoneuron, ventral cord neurons, and several chemosensory neurons. [Source: WormBase] |
| C53C9.3 | C53C9.3b | kvs-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | kvs-1 encodes a voltage-gated, A-type potassium channel. kvs-1 is required for the normal function of several neurons and thus for normal forward locomotion, chemotaxis to select molecules, osmotic avoidance, and nose-touch. when expressed in tissue culture cells, KVS-1 exhibits potassium-selective channel activity that is altered by coexpression with C. elegans MPS-1, -2, -3, and -4, KCNE-like ancillary subunits, or a related human protein, hMiRP1. in addition, KVS-1 forms a functional complex with MPS-1 in the ASER neuron and activity of MPS-2, MPS-3, and KVS-1 coexpressed in culture suggests that these three proteins can form a functional ternary complex that genetic analyses indicate likely plays a role in regulating responsiveness to sodium. kvs-1 reporter fusions are expressed in sperm, the anal depressor muscle, the PDA motoneuron, ventral cord neurons, and several chemosensory neurons. [Source: WormBase] |
| C53C9.3 | C53C9.3c | kvs-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | kvs-1 encodes a voltage-gated, A-type potassium channel. kvs-1 is required for the normal function of several neurons and thus for normal forward locomotion, chemotaxis to select molecules, osmotic avoidance, and nose-touch. when expressed in tissue culture cells, KVS-1 exhibits potassium-selective channel activity that is altered by coexpression with C. elegans MPS-1, -2, -3, and -4, KCNE-like ancillary subunits, or a related human protein, hMiRP1. in addition, KVS-1 forms a functional complex with MPS-1 in the ASER neuron and activity of MPS-2, MPS-3, and KVS-1 coexpressed in culture suggests that these three proteins can form a functional ternary complex that genetic analyses indicate likely plays a role in regulating responsiveness to sodium. kvs-1 reporter fusions are expressed in sperm, the anal depressor muscle, the PDA motoneuron, ventral cord neurons, and several chemosensory neurons. [Source: WormBase] |
| C54D1.3 | C54D1.3 | ist-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | ist-1 encodes a pleckstrin homology (PH) and phosphotyrosine binding (PTB) domain-containing insulin receptor substrate (IRS) homolog that negatively regulates lifespan and dauer development. IST-1 potentiates insulin-like signaling, although it is not absolutely required for such signaling under most conditions. in addition to acting through the AGE-1/PI3K branch of the insulin-like signaling pathway, IST-1 may also function in a parallel pathway to activate downstream protein-kinase Bs encoded by akt-1 and akt-2. [Source: WormBase] |
| C54D2.5 | C54D2.5a | cca-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | cca-1 encodes a calcium channel alpha subunit that is homologous to vertebrate T-type calcium channel alpha 1 subunits. CCA-1 is required for regulation of pharyngeal pumping, specifically for the efficient initiation of action potentials in the pharynx in response to excitatory inputs. a CCA-1::GFP fusion protein is expressed strongly in pharyngeal muscle as well as in many neurons, including particular subsets of neurons in the head, pharynx, ventral nerve cord, and anal ganglia. [Source: WormBase] |
| C54D2.5 | C54D2.5c | cca-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | cca-1 encodes a calcium channel alpha subunit that is homologous to vertebrate T-type calcium channel alpha 1 subunits. CCA-1 is required for regulation of pharyngeal pumping, specifically for the efficient initiation of action potentials in the pharynx in response to excitatory inputs. a CCA-1::GFP fusion protein is expressed strongly in pharyngeal muscle as well as in many neurons, including particular subsets of neurons in the head, pharynx, ventral nerve cord, and anal ganglia. [Source: WormBase] |
| C54D2.5 | C54D2.5d | cca-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | cca-1 encodes a calcium channel alpha subunit that is homologous to vertebrate T-type calcium channel alpha 1 subunits. CCA-1 is required for regulation of pharyngeal pumping, specifically for the efficient initiation of action potentials in the pharynx in response to excitatory inputs. a CCA-1::GFP fusion protein is expressed strongly in pharyngeal muscle as well as in many neurons, including particular subsets of neurons in the head, pharynx, ventral nerve cord, and anal ganglia. [Source: WormBase] |
| C54D2.5 | C54D2.5e | cca-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | cca-1 encodes a calcium channel alpha subunit that is homologous to vertebrate T-type calcium channel alpha 1 subunits. CCA-1 is required for regulation of pharyngeal pumping, specifically for the efficient initiation of action potentials in the pharynx in response to excitatory inputs. a CCA-1::GFP fusion protein is expressed strongly in pharyngeal muscle as well as in many neurons, including particular subsets of neurons in the head, pharynx, ventral nerve cord, and anal ganglia. [Source: WormBase] |
| C54D2.5 | C54D2.5f | cca-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | cca-1 encodes a calcium channel alpha subunit that is homologous to vertebrate T-type calcium channel alpha 1 subunits. CCA-1 is required for regulation of pharyngeal pumping, specifically for the efficient initiation of action potentials in the pharynx in response to excitatory inputs. a CCA-1::GFP fusion protein is expressed strongly in pharyngeal muscle as well as in many neurons, including particular subsets of neurons in the head, pharynx, ventral nerve cord, and anal ganglia. [Source: WormBase] |
| C55B6.1 | C55B6.1a | C55B6.1 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C55B6.1 | C55B6.1b | C55B6.1 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C55B6.2 | C55B6.2 | dnj-7 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | dnj-7 encodes a protein containing a DnaJ domain that is orthologous to vertebrate P58IPK/DNAJC3, peripheral membrane proteins of the rough endoplasmic reticulum (ER) that function in cotranslocational ER protein degradation during ER stress. in C. elegans, loss of dnj-7 activity via RNAi results in increased expression of an hsp-4::gfp (BiP) stress-inducible reporter fusion, suggesting that dnj-7 functions to regulate ER homeostasis. [Source: WormBase] |
| D1005.2 | D1005.2 | D1005.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| D1009.3 | D1009.3a | D1009.3 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| D1009.3 | D1009.3b | D1009.3 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| D1009.4 | D1009.4.1 | nlp-14 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| D1053.1 | D1053.1 | gst-42 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | gst-42 is orthologous to the human gene GLUTATHIONE TRANSFERASE ZETA-1 (also known as MALEYLACETOACETATE ISOMERASE. GSTZ1. OMIM:603758), which when mutated is thought to lead to a variety of type I tyrosinemia. [Source: WormBase] |
| D2021.1 | D2021.1 | utx-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | utx-1 encodes a putative histone H3 di/trimethyllysine-27 (H3K27me2/me3) demethylase, required for embryonic viability and vulval development, and for high brood sizes, locomotion, and growth sizes. UTX-1 contains a JmjC domain, is orthologous to human UTX and UTY, and is paralogous to human JMJD3. by orthology, UTX-1 is expected to antagonize transcriptional repression by polycomb repressor complexes, which mark stem cells (and presumably germline) by H3K27me3-mediated repression of somatic genes. [Source: WormBase] |
| E03E2.1 | E03E2.1.1 | cyp-43A1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| E03E2.1 | E03E2.1.2 | cyp-43A1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| F01E11.3 | F01E11.3 | F01E11.3 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| F01G12.5 | F01G12.5a | let-2 | 3 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | let-2 encodes an alpha-2 type IV collagen, probably most closely equivalent to the human gene COL4A2 (OMIM:120090) on the basis of biological function. LET-2 is required for embryonic development and is a component of the basement membrane between muscle and hypodermis. LET-2 interacts with UNC-105, a mechanosensory ion channel of the degenerin ion channel superfamily that is expressed in muscle and required for normal growth, muscle contraction, and muscle organization. let-2 activity is governed, in part, by ASD-2-mediated, developmentally regulated alternative splicing in which exon nine is used in embryos and exon 10 in late larvae and adults. [Source: WormBase] |
| F02C12.1 | F02C12.1 | F02C12.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl |