| Gene ID | Transcript ID | Common Gene Name | # of miRNA targets for specified miRNAs | Chromosome | Strand Direction | Transcript Link to view miRNA target predictions | Gene Link | Description |
|---|---|---|---|---|---|---|---|---|
| AC8.11 | AC8.11 | AC8.11 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| AC8.4 | AC8.4 | AC8.4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| AH9.1 | AH9.1 | AH9.1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| AH9.2 | AH9.2 | crn-4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| B0198.1 | B0198.1 | tsp-20 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| B0198.3 | B0198.3a | B0198.3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| B0302.4 | B0302.4 | B0302.4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| B0310.1 | B0310.1b | B0310.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | B0310.1 encodes a nematode-specific transmembrane protein. loss of B0310.1 activity via RNAi results in reduced fat content in wild-type and tub-1 mutant animals, suggesting that B0301.1 plays a role in lipid metabolism. [Source: WormBase] |
| B0310.2 | B0310.2.1 | B0310.2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| B0310.2 | B0310.2.2 | B0310.2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| B0403.2 | B0403.2 | ubc-17 | 3 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0403.4 | B0403.4 | tag-320 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| B0410.3 | B0410.3 | B0410.3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| B0416.3 | B0416.3 | B0416.3 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0416.5 | B0416.5a | B0416.5 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| B0416.5 | B0416.5b | B0416.5 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| B0416.6 | B0416.6 | gly-13 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | gly-13 encodes an experimentally verified UDP-N-acetylglucosamine alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I (GnT I), that is the primary GnT I enzyme in vivo, and that can act on unusual substrates. gly-13 is expressed throughout development in many cell types. gly-13 has no obvious function in vivo, since a deletion allele of gly-13 is phenotypically normal even as a double or triple mutant with gly-12 and gly-14. [Source: WormBase] |
| C01C10.2 | C01C10.2a | C01C10.2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C01C10.3 | C01C10.3.1 | acl-12 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C01C10.3 | C01C10.3.2 | acl-12 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C01C10.4 | C01C10.4 | clc-5 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | clc-5 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia. CLC-5 is worm-specific, with obvious homologs only in C. elegans. CLC-5 has no obvious function in mass RNAi assays. claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water. [Source: WormBase] |
| C01C4.2 | C01C4.2 | C01C4.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C02B4.1 | C02B4.1 | adt-1 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | The adt-1 gene encodes a metalloproteinase with disintegrin-like and metalloproteinase with thrombospondin type I motifs (ADAMTS) that is required for male tail morphogenesis. [Source: WormBase] |
| C02B8.6 | C02B8.6 | C02B8.6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C02C6.1 | C02C6.1a | dyn-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | dyn-1 encodes the C. elegans ortholog of the dynamin GTPase. dyn-1 activity is required for endocytosis, synaptic vesicle recycling, cytokinesis, and the CED-1 pathway that regulates engulfment and degradation of apoptotic cells. mutations in dyn-1 affect locomotion, egg-laying, defecation, and embryonic development, indicating that dyn-1's endocytic function is required for a number of diverse processes. dyn-1 reporter fusion constructs are expressed in motor neurons, intestinal cells, and pharyngeal muscle. [Source: WormBase] |
| C02C6.1 | C02C6.1b | dyn-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | dyn-1 encodes the C. elegans ortholog of the dynamin GTPase. dyn-1 activity is required for endocytosis, synaptic vesicle recycling, cytokinesis, and the CED-1 pathway that regulates engulfment and degradation of apoptotic cells. mutations in dyn-1 affect locomotion, egg-laying, defecation, and embryonic development, indicating that dyn-1's endocytic function is required for a number of diverse processes. dyn-1 reporter fusion constructs are expressed in motor neurons, intestinal cells, and pharyngeal muscle. [Source: WormBase] |
| C02F12.4 | C02F12.4 | tag-52 | 3 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C02F12.8 | C02F12.8 | C02F12.8 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C02F12.9 | C02F12.9 | C02F12.9 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C03B1.14 | C03B1.14 | C03B1.14 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C03B1.1 | C03B1.1 | C03B1.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C03B1.4 | C03B1.4 | C03B1.4 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C03B1.7 | C03B1.7 | C03B1.7 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C03F11.4 | C03F11.4.1 | C03F11.4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C03F11.4 | C03F11.4.2 | C03F11.4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C03F11.4 | C03F11.4.3 | C03F11.4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C03G5.1 | C03G5.1.1 | sdha-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | sdha-1 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT A, FLAVOPROTEIN (SDHA. OMIM:600857), which when mutated leads to complex II mitochondrial respiratory chain deficiency presenting as Leigh syndrome. [Source: WormBase] |
| C03G5.1 | C03G5.1.2 | sdha-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | sdha-1 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT A, FLAVOPROTEIN (SDHA. OMIM:600857), which when mutated leads to complex II mitochondrial respiratory chain deficiency presenting as Leigh syndrome. [Source: WormBase] |
| C04A11.2 | C04A11.2 | C04A11.2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C04A11.3 | C04A11.3 | gck-4 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C04B4.2 | C04B4.2 | C04B4.2 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C04B4.4 | C04B4.4 | C04B4.4 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C04E7.2 | C04E7.2 | sor-3 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | sor-3 encodes a novel protein that contains an MBT (malignant brain tumor) domain related to the MBT domains found in the Sex comb on midleg (SCM) and Sfmbt Polycomb group proteins. during development, SOR-3 activity is required to specify the correct number of dopaminergic and serotonergic neurons in males, as well as for proper ray neuron axon guidance, distal tip cell migration, and normal body size. SOR-3 activity is necessary for maintaining repression of Hox gene expression, notably that of egl-5 in many head neurons. in regulating neurotransmitter phenotype, sor-3 functions together with sop-2, which also encodes a Polycomb group protein, and members of the TGF-beta signaling pathway. sor-3 and sop-2 also function together to regulate progression through larval development. a SOR-3::GFP reporter fusion is expressed ubiquitously throughout the life cycle and localizes to both the cytoplasm and the nucleus. [Source: WormBase] |
| C04E7.3 | C04E7.3 | C04E7.3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C04F6.1 | C04F6.1 | vit-5 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | vit-5 encodes a vitellogenin, a lipid-binding protein precursor related to vertebrate vitellogenins and mammalian ApoB-100, a core LDL particle constituent. by homology, VIT-5 is predicted to function as a lipid transport protein. loss of vit-5 activity via large-scale RNA-mediated interference (RNAi) screens indicates that VIT-5 is required for embryogenesis and normal rates of postembryonic growth. VIT-5 is a major yolk component and is expressed exclusively in the adult hermaphrodite intestine from which it is secreted into the pseudocoelomic space and taken up by oocytes. [Source: WormBase] |
| C04F6.3 | C04F6.3.1 | cht-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | cht-1 encodes a chitinase orthologous to human chitinase-1 (OMIM:600031, mutations are associated with chitotriosidase deficiency). CHT-1 is predicted to function as an extracellular O-glycosyl hydrolase that hydrolyzes the glycosidic bond between two or more carbohydrates. in C. elegans, CHT-1 may play a role in embryogenesis, and may also be required for cuticle degradation during molting and degradation of chitin-containing pathogens as part of a host defense mechanism. [Source: WormBase] |
| C04F6.3 | C04F6.3.2 | cht-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | cht-1 encodes a chitinase orthologous to human chitinase-1 (OMIM:600031, mutations are associated with chitotriosidase deficiency). CHT-1 is predicted to function as an extracellular O-glycosyl hydrolase that hydrolyzes the glycosidic bond between two or more carbohydrates. in C. elegans, CHT-1 may play a role in embryogenesis, and may also be required for cuticle degradation during molting and degradation of chitin-containing pathogens as part of a host defense mechanism. [Source: WormBase] |
| C05C9.3 | C05C9.3 | C05C9.3 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77). [Source: WormBase] |
| C05D9.2 | C05D9.2.1 | lmp-2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | lmp-2 encodes a transmembrane protein that is one of two C. elegans LAMP (lysosomal associated membrane glycoprotein) homologs. [Source: WormBase] |
| C05D9.2 | C05D9.2.2 | lmp-2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | lmp-2 encodes a transmembrane protein that is one of two C. elegans LAMP (lysosomal associated membrane glycoprotein) homologs. [Source: WormBase] |
| C05D9.2 | C05D9.2.3 | lmp-2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | lmp-2 encodes a transmembrane protein that is one of two C. elegans LAMP (lysosomal associated membrane glycoprotein) homologs. [Source: WormBase] |
| C05E11.4 | C05E11.4 | amt-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | amt-1 encodes a transmembrane transporter that by homology, is predicted to transport ammonium ions across the plasma membrane. as loss of amt-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of AMT-1 in C. elegans development and/or behavior is not yet known. [Source: WormBase] |
| C05E11.7 | C05E11.7 | C05E11.7 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C06E2.1 | C06E2.1 | C06E2.1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C06G1.4 | C06G1.4.1 | ain-1 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | ain-1 encodes an unfamiliar protein synergistically required, with LIN-31, for the normal timing of vulval differentiation, independently of LET-60/RAS, and parallel to or downstream of LIN-14/LIN-28/HBL-1. AIN-1 is expressed in cytoplasmic foci (that are probably P bodies) in several tissues, including vulval precursor cells and neurons. AIN-1 coimmunoprecipitates with DCR-1 and ALG-1, also binds ALG-1 in vitro, and does not require DNA or RNA for its binding. in vivo, AIN-1 targets ALG-1 to cytoplasmic foci, in which it colocalizes with DCAP-2. AIN-1 is likely to be a RISC component, since anti-AIN-1 antibodies precipitate 29 different miRNAs, including mir-2, mir-52, mir-58, mir-71, mir-77, and mir-239a. ain-1(ku322) mutants are essentially wild-type, except for sporadically gapped alae and excess seam cell nuclei arising from retarded seam cell fusion. more prominently, ain-1(ku322) suppresses the multivulva phenotype of lin-31(n1053) mutations, while strongly enhancing lin-31(n1053)'s egg-laying defect. the cellular basis of lin-31(n1053).ain-1(ku322) phenotypes is a delay in vulval development in L4 larvae not seen with either mutation alone. ain-1(ku322) has no effect on let-60(n1046) or lin-3(e1275) mutations. ain-1(ku322) suppresses the precocious vulval development of lin-14(RNAi), lin-28 mutants, and hbl-1(RNAi). alg-1 or alg-1 ain-1 mutant alae resemble ain-1 alae, indicating that ALG-1 and AIN-1 act in a common genetic pathway. AIN-1 is homologous to Brugia malayi 14748.m00068, 14052.m00191, and 14963.m01790, and paralogous to C. elegans B0041.2. AIN-1 and its nematode homologs have weak similarity to human TNRC6A (GW182. OMIM:610739) and Drosophila GAWKY. [Source: WormBase] |
| C06G1.4 | C06G1.4.2 | ain-1 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | ain-1 encodes an unfamiliar protein synergistically required, with LIN-31, for the normal timing of vulval differentiation, independently of LET-60/RAS, and parallel to or downstream of LIN-14/LIN-28/HBL-1. AIN-1 is expressed in cytoplasmic foci (that are probably P bodies) in several tissues, including vulval precursor cells and neurons. AIN-1 coimmunoprecipitates with DCR-1 and ALG-1, also binds ALG-1 in vitro, and does not require DNA or RNA for its binding. in vivo, AIN-1 targets ALG-1 to cytoplasmic foci, in which it colocalizes with DCAP-2. AIN-1 is likely to be a RISC component, since anti-AIN-1 antibodies precipitate 29 different miRNAs, including mir-2, mir-52, mir-58, mir-71, mir-77, and mir-239a. ain-1(ku322) mutants are essentially wild-type, except for sporadically gapped alae and excess seam cell nuclei arising from retarded seam cell fusion. more prominently, ain-1(ku322) suppresses the multivulva phenotype of lin-31(n1053) mutations, while strongly enhancing lin-31(n1053)'s egg-laying defect. the cellular basis of lin-31(n1053).ain-1(ku322) phenotypes is a delay in vulval development in L4 larvae not seen with either mutation alone. ain-1(ku322) has no effect on let-60(n1046) or lin-3(e1275) mutations. ain-1(ku322) suppresses the precocious vulval development of lin-14(RNAi), lin-28 mutants, and hbl-1(RNAi). alg-1 or alg-1 ain-1 mutant alae resemble ain-1 alae, indicating that ALG-1 and AIN-1 act in a common genetic pathway. AIN-1 is homologous to Brugia malayi 14748.m00068, 14052.m00191, and 14963.m01790, and paralogous to C. elegans B0041.2. AIN-1 and its nematode homologs have weak similarity to human TNRC6A (GW182. OMIM:610739) and Drosophila GAWKY. [Source: WormBase] |
| C08A9.1 | C08A9.1 | sod-3 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | sod-3 encodes a iron/manganese superoxide dismutase, predicted to be mitochondrial, that might defend against oxidative stress and promote normal lifespan. sod-3 mRNA levels are diminished by mutation of daf-16 and chromatin immunoprecipitation (ChIP) studies demonstrate that DAF-16 can directly bind the sod-3 promoter. heterologously expressed SOD-3 in E. coli protects against methyl viologen-induced oxidative stress. [Source: WormBase] |
| C08A9.9 | C08A9.9.1 | C08A9.9 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C08A9.9 | C08A9.9.2 | C08A9.9 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C09F12.1 | C09F12.1.1 | clc-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | clc-1 encodes a claudin homolog, closely similar to CLC-2, that is required for normal cohesion of apical junctions in epithelia. claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water. CLC-1 maintains the impermeability ('barrier function') of epithelia, since clc-1(RNAi) animals have abnormal permeability of the pharynx to dyes. clc-1 is expressed in spermatheca, pharynx, intestine, hypodermis, the excretory-secretory system, and the cell-cell junctions of the vulva. in pharyngeal cells, CLC-1 colocalizes with AJM-1 in long thin lines, parallel to the pharyngeal axis and lining the lumenal surface, that appear to correspond with apical intercellular junctions. [Source: WormBase] |
| C09F12.1 | C09F12.1.2 | clc-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | clc-1 encodes a claudin homolog, closely similar to CLC-2, that is required for normal cohesion of apical junctions in epithelia. claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water. CLC-1 maintains the impermeability ('barrier function') of epithelia, since clc-1(RNAi) animals have abnormal permeability of the pharynx to dyes. clc-1 is expressed in spermatheca, pharynx, intestine, hypodermis, the excretory-secretory system, and the cell-cell junctions of the vulva. in pharyngeal cells, CLC-1 colocalizes with AJM-1 in long thin lines, parallel to the pharyngeal axis and lining the lumenal surface, that appear to correspond with apical intercellular junctions. [Source: WormBase] |
| C09G1.5 | C09G1.5.1 | C09G1.5 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C09G1.5 | C09G1.5.2 | C09G1.5 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C09G1.5 | C09G1.5.3 | C09G1.5 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C10A4.1 | C10A4.1 | C10A4.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C10E2.2 | C10E2.2.1 | C10E2.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins. [Source: WormBase] |
| C10E2.6 | C10E2.6.1 | C10E2.6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C10E2.6 | C10E2.6.2 | C10E2.6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C11E4.1 | C11E4.1 | C11E4.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C11E4.6 | C11E4.6.1 | C11E4.6 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C11E4.6 | C11E4.6.2 | C11E4.6 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C11H1.9 | C11H1.9a | C11H1.9 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C11H1.9 | C11H1.9b | C11H1.9 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C12D12.2 | C12D12.2a.1 | glt-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | glt-1 encodes a predicted plasma membrane glutamate transporter that is functional when expressed in Xenopus oocytes. expressed in the M3 pharyngeal neuron, the male tail, some anterior hypodermal cells, and in cells in the terminal bulb of the pharynx. [Source: WormBase] |
| C12D12.2 | C12D12.2a.2 | glt-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | glt-1 encodes a predicted plasma membrane glutamate transporter that is functional when expressed in Xenopus oocytes. expressed in the M3 pharyngeal neuron, the male tail, some anterior hypodermal cells, and in cells in the terminal bulb of the pharynx. [Source: WormBase] |
| C13E3.1 | C13E3.1 | C13E3.1 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C14A11.3 | C14A11.3a | cgef-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C14A11.3 | C14A11.3b | cgef-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C14A11.3 | C14A11.3c | cgef-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C14A11.5 | C14A11.5 | C14A11.5 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C14E2.4 | C14E2.4 | C14E2.4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C14E2.6 | C14E2.6 | C14E2.6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C14F11.2 | C14F11.2 | C14F11.2 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C14F5.5 | C14F5.5 | sem-5 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | sem-5 encodes a Src homology (SH) domain 2 and 3-containing protein, orthologous to human GRB2 (OMIM:108355) and Drosophila Drk. sem-5 functions in multiple signaling pathways during development including those regulating sex myoblast migration, muscle membrane extension, vulval induction, fluid balance, viability, and formation of the male tail. SEM-5 acts downstream of the LET-23 epidermal growth factor receptor to negatively regulate RAS-, MAP-, and IP-3-, mediated signal transduction. a sem-5::yfp promoter fusion is expressed in many cells throughout development, including the hypodermis, intestine, neurons, body wall muscles, and vulval precursor cells. [Source: WormBase] |
| C14H10.3 | C14H10.3a | C14H10.3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C14H10.3 | C14H10.3b.1 | C14H10.3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C14H10.3 | C14H10.3b.2 | C14H10.3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C15A7.1 | C15A7.1 | lgc-23 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C15H9.1 | C15H9.1 | nnt-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | nnt-1 encodes a proton-pumping nicotinamide nucleotide transhydrogenase predicted to be mitochondrial. [Source: WormBase] |
| C15H9.6 | C15H9.6.1 | hsp-3 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | hsp-3 encodes one of two C. elegans heat shock response 70 (hsp70) proteins homologous to mammalian grp78/BiP (glucose regulated protein 78/immunoglobulin heavy chain-binding protein, OMIM:138120). HSP-3 likely functions as a molecular chaperone, and is expressed constitutively (expression is not heat inducible) throughout development with greatest abundance during the L1 larval stage. hsp-3 transcription is, however, upregulated in response to endoplasmic reticulum stress induced by dithiothreitol (DTT) or tunicamycin. HSP-3 contains a long hydrophobic amino terminus and a carboxyl terminal KDEL sequence suggesting that it may be retained in the endoplasmic reticulum. [Source: WormBase] |
| C15H9.6 | C15H9.6.2 | hsp-3 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | hsp-3 encodes one of two C. elegans heat shock response 70 (hsp70) proteins homologous to mammalian grp78/BiP (glucose regulated protein 78/immunoglobulin heavy chain-binding protein, OMIM:138120). HSP-3 likely functions as a molecular chaperone, and is expressed constitutively (expression is not heat inducible) throughout development with greatest abundance during the L1 larval stage. hsp-3 transcription is, however, upregulated in response to endoplasmic reticulum stress induced by dithiothreitol (DTT) or tunicamycin. HSP-3 contains a long hydrophobic amino terminus and a carboxyl terminal KDEL sequence suggesting that it may be retained in the endoplasmic reticulum. [Source: WormBase] |
| C15H9.6 | C15H9.6.3 | hsp-3 | 3 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | hsp-3 encodes one of two C. elegans heat shock response 70 (hsp70) proteins homologous to mammalian grp78/BiP (glucose regulated protein 78/immunoglobulin heavy chain-binding protein, OMIM:138120). HSP-3 likely functions as a molecular chaperone, and is expressed constitutively (expression is not heat inducible) throughout development with greatest abundance during the L1 larval stage. hsp-3 transcription is, however, upregulated in response to endoplasmic reticulum stress induced by dithiothreitol (DTT) or tunicamycin. HSP-3 contains a long hydrophobic amino terminus and a carboxyl terminal KDEL sequence suggesting that it may be retained in the endoplasmic reticulum. [Source: WormBase] |
| C16B8.1 | C16B8.1.1 | lin-18 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | lin-18 encodes a predicted receptor tyrosine kinase that is a member of the Ryk/Derailed family of tyrosine kinase-related receptors (OMIM:600524, mutations in humans are associated with cleft palate). in C. elegans, LIN-18 is required for establishing the polarity of the secondary vulval cell lineage produced by the P7.p vulval precursor cell. LIN-18 may be a receptor for Wnt-like signaling molecules, and in vulval development appears to function independently of, but in parallel with, LIN-17, a Frizzled-like Wnt receptor, also required for proper orientation of the P7.p lineage. a lin-18 reporter gene is expressed in body wall muscle, neurons, and the developing vulva. in the vulva, expression is detected in P5.p, P6.p, and P7.p and all of their descendants during the L3 and L4 larval stages. [Source: WormBase] |
| C16B8.1 | C16B8.1.2 | lin-18 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | lin-18 encodes a predicted receptor tyrosine kinase that is a member of the Ryk/Derailed family of tyrosine kinase-related receptors (OMIM:600524, mutations in humans are associated with cleft palate). in C. elegans, LIN-18 is required for establishing the polarity of the secondary vulval cell lineage produced by the P7.p vulval precursor cell. LIN-18 may be a receptor for Wnt-like signaling molecules, and in vulval development appears to function independently of, but in parallel with, LIN-17, a Frizzled-like Wnt receptor, also required for proper orientation of the P7.p lineage. a lin-18 reporter gene is expressed in body wall muscle, neurons, and the developing vulva. in the vulva, expression is detected in P5.p, P6.p, and P7.p and all of their descendants during the L3 and L4 larval stages. [Source: WormBase] |
| C16B8.2 | C16B8.2.1 | C16B8.2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C16B8.2 | C16B8.2.2 | C16B8.2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C16H3.3 | C16H3.3a | C16H3.3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C17G1.1 | C17G1.1 | C17G1.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C17G1.5 | C17G1.5 | C17G1.5 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C17H11.4 | C17H11.4 | C17H11.4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl |