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Genome: Caenorhabditis Elegans | mRNA | miRBase 18 (Nov. 2011), ENSEMBL 65 (Dec. 2011) and RNA22v1.0
Description: List of transcripts that are targeted by all of the below miRNA identifiers simultaneously
miRNA's: cel-miR-239b-3p (MIMAT0015115)
Filtering By: Base pair min value: 12 | Folding energy max value (Kcal/mol): -21 | Min miRNA targets: 1


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Gene IDTranscript IDCommon Gene Name# of miRNA targets
for specified miRNAs
ChromosomeStrand DirectionTranscript Link to view miRNA target predictionsGene LinkDescription
AC8.10AC8.10AC8.10223 XReverseView as cDNA map |
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Ensembl
AC8.11AC8.11AC8.11123 XReverseView as cDNA map |
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Ensembl
AC8.3AC8.3AC8.3223 XReverseView as cDNA map |
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Ensembl
AC8.4AC8.4AC8.4123 XReverseView as cDNA map |
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Ensembl
B0198.1B0198.1tsp-20323 XReverseView as cDNA map |
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Ensembl
B0198.2B0198.2aB0198.2123 XForwardView as cDNA map |
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Ensembl
B0198.2B0198.2bB0198.2123 XForwardView as cDNA map |
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Ensembl
B0198.3B0198.3aB0198.3223 XReverseView as cDNA map |
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B0272.4B0272.4B0272.4223 XForwardView as cDNA map |
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B0302.1B0302.1a.1kin-25223 XForwardView as cDNA map |
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Ensembl
kin-25 encodes a nonreceptor tyrosine kinase that is a member of the Ack subfamily of cytoplasmic tyrosine kinases. [Source: WormBase]
B0302.1B0302.1a.2kin-25223 XForwardView as cDNA map |
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Ensembl
kin-25 encodes a nonreceptor tyrosine kinase that is a member of the Ack subfamily of cytoplasmic tyrosine kinases. [Source: WormBase]
B0302.1B0302.1bkin-25223 XForwardView as cDNA map |
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Ensembl
kin-25 encodes a nonreceptor tyrosine kinase that is a member of the Ack subfamily of cytoplasmic tyrosine kinases. [Source: WormBase]
B0310.1B0310.1bB0310.1123 XForwardView as cDNA map |
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Ensembl
B0310.1 encodes a nematode-specific transmembrane protein. loss of B0310.1 activity via RNAi results in reduced fat content in wild-type and tub-1 mutant animals, suggesting that B0301.1 plays a role in lipid metabolism. [Source: WormBase]
B0310.2B0310.2.1B0310.2123 XReverseView as cDNA map |
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B0310.2B0310.2.2B0310.2123 XReverseView as cDNA map |
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Ensembl
B0310.3B0310.3B0310.3123 XReverseView as cDNA map |
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Ensembl
B0344.2B0344.2wrt-9123 XForwardView as cDNA map |
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Ensembl
wrt-9 encodes a hedgehog-like protein, with an N-terminal signal sequence, a Wart domain, and a C-terminal region of proline-rich, low-complexity sequence. the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins. WRT-9 has no obvious function in RNAi assays. [Source: WormBase]
B0395.1B0395.1nhx-1123 XForwardView as cDNA map |
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Ensembl
nhx-1 encodes a sodium/proton exchanger expressed intracellularly within hypodermal and muscle cells. NHX-1 is required for embryonic viability, and is thought to prevent intracellular acidification by catalysing the electroneutral exchange of vesicular sodium for an intracellular proton. [Source: WormBase]
B0403.2B0403.2ubc-17223 XForwardView as cDNA map |
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B0403.3B0403.3B0403.3123 XReverseView as cDNA map |
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B0403.4B0403.4tag-320123 XReverseView as cDNA map |
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B0416.1B0416.1B0416.1223 XForwardView as cDNA map |
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B0416.5B0416.5aB0416.5123 XReverseView as cDNA map |
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B0416.5B0416.5bB0416.5123 XReverseView as cDNA map |
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B0416.6B0416.6gly-13223 XReverseView as cDNA map |
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gly-13 encodes an experimentally verified UDP-N-acetylglucosamine alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I (GnT I), that is the primary GnT I enzyme in vivo, and that can act on unusual substrates. gly-13 is expressed throughout development in many cell types. gly-13 has no obvious function in vivo, since a deletion allele of gly-13 is phenotypically normal even as a double or triple mutant with gly-12 and gly-14. [Source: WormBase]
B0416.7B0416.7aB0416.7123 XReverseView as cDNA map |
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B0416.7B0416.7bB0416.7123 XReverseView as cDNA map |
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B0563.1B0563.1B0563.1123 XForwardView as cDNA map |
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Ensembl
B0563.2B0563.2tsp-11123 XForwardView as cDNA map |
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B0563.7B0563.7B0563.7123 XReverseView as cDNA map |
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B0563.8B0563.8B0563.8123 XReverseView as cDNA map |
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C01C10.2C01C10.2bC01C10.2123 XReverseView as cDNA map |
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C01C10.3C01C10.3.1acl-12123 XReverseView as cDNA map |
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C01C10.3C01C10.3.2acl-12123 XReverseView as cDNA map |
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C01C4.3C01C4.3bC01C4.3523 XForwardView as cDNA map |
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C01C4.3 encodes a serine/threonine protein kinase. [Source: WormBase]
C02B4.1C02B4.1adt-1523 XForwardView as cDNA map |
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The adt-1 gene encodes a metalloproteinase with disintegrin-like and metalloproteinase with thrombospondin type I motifs (ADAMTS) that is required for male tail morphogenesis. [Source: WormBase]
C02B4.2C02B4.2nhr-17123 XReverseView as cDNA map |
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nhr-17 encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators. nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain. [Source: WormBase]
C02B8.5C02B8.5C02B8.5323 XReverseView as cDNA map |
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C02B8.5 encodes a homolog of the functionally active Fmrf Receptor (FR. CG2114) of D. melanogaster. it is thus possible that C02B8.5 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12). [Source: WormBase]
C02C6.1C02C6.1adyn-1223 XForwardView as cDNA map |
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dyn-1 encodes the C. elegans ortholog of the dynamin GTPase. dyn-1 activity is required for endocytosis, synaptic vesicle recycling, cytokinesis, and the CED-1 pathway that regulates engulfment and degradation of apoptotic cells. mutations in dyn-1 affect locomotion, egg-laying, defecation, and embryonic development, indicating that dyn-1's endocytic function is required for a number of diverse processes. dyn-1 reporter fusion constructs are expressed in motor neurons, intestinal cells, and pharyngeal muscle. [Source: WormBase]
C02C6.1C02C6.1bdyn-1223 XForwardView as cDNA map |
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dyn-1 encodes the C. elegans ortholog of the dynamin GTPase. dyn-1 activity is required for endocytosis, synaptic vesicle recycling, cytokinesis, and the CED-1 pathway that regulates engulfment and degradation of apoptotic cells. mutations in dyn-1 affect locomotion, egg-laying, defecation, and embryonic development, indicating that dyn-1's endocytic function is required for a number of diverse processes. dyn-1 reporter fusion constructs are expressed in motor neurons, intestinal cells, and pharyngeal muscle. [Source: WormBase]
C02C6.2C02C6.2bolrn-1123 XForwardView as cDNA map |
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olrn-1 encodes, by alternative splicing, two isoforms of a transmembrane protein required for differentiation of the AWC[ON] neuron, expression of str-2 in AWC[ON], adaptation to benzaldehyde, chemotaxis to butanone, and enhancement of chemotaxis to butanone by the presence of food. OLRN-1 is orthologous to Drosophila melanogaster RAW and Schistosoma japonicum SJCHGC05616. while OLRN-1 has orthologs in nematodes, trematodes, and arthropods, its has no obvious chordate homologs. OLRN-6 is expressed in many pharyngeal neurons and some head neurons, but is required solely in the AWC[ON] neuron for butanone enhancement. OLRN-6's function in butanone enhancement is both serotonin- and dopamine-independent, and appears to also act in chemotactic enhancement of 2,3-pentanedione and isoamyl alcohol. by orthology with RAW, OLRN-6 is predicted to inhibit JNK-1 signalling, which may in turn allow the asymmetrical AWC[ON] fate to emerge. [Source: WormBase]
C02C6.3C02C6.3aC02C6.3123 XReverseView as cDNA map |
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C02C6.3C02C6.3bC02C6.3123 XReverseView as cDNA map |
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C02C6.3C02C6.3cC02C6.3123 XReverseView as cDNA map |
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C02C6.3C02C6.3d.1C02C6.3123 XReverseView as cDNA map |
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C02C6.3C02C6.3d.2C02C6.3123 XReverseView as cDNA map |
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C02D4.1C02D4.1jud-4123 XForwardView as cDNA map |
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jud-4 encodes an unfamiliar protein, putatively secreted, that is required both for normal sensitivity to ethanol and for survival after freezing and thawing. JUD-4 is expressed in hypodermis and vulval muscles. JUD-4 is orthologous to Brugia malayi Bm1_40315, but lacks obvious orthologies to non-nematode proteins. JUD-4's C-terminal domain has possible similarity to F40E10.5, and to proteins such as human HOMER1. jud-4(ys18) mutants show delayed sensitivity to ethanol levels that rapidly paralyze normal worms, but do not survive freezing and rethawing as does wild-type. JUD-4 has no obvious function in mass RNAi assays. [Source: WormBase]
C02F12.1C02F12.1atsp-17123 XForwardView as cDNA map |
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Ensembl
C02F12.1C02F12.1btsp-17123 XForwardView as cDNA map |
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C02F12.4C02F12.4tag-52123 XReverseView as cDNA map |
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C02F12.7C02F12.7tag-278123 XReverseView as cDNA map |
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C02F12.8C02F12.8C02F12.8123 XReverseView as cDNA map |
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C02F12.9C02F12.9C02F12.9123 XForwardView as cDNA map |
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C02H7.1C02H7.1dyf-11123 XForwardView as cDNA map |
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dyf-11 encodes a conserved protein orthologous to the human microtubule-binding protein MIP-T3 and that contains a lysine-rich region and a C-terminal coiled-coil domain present in a number of intraflagellar transport (IFT) complex B proteins. DYF-11 activity is required continuously in sensory neurons for formation of medial and distal ciliary segments and thus, for normal sensory cilium morphology and function and chemotaxis. a dyf-11::gfp promoter fusion is expressed in all ciliated sensory neurons as well as in the AQR, PQR, ADE, and PDR neurons. a DYF-11::GFP protein fusion is detected throughout the cilium and appears to localize to IFT-B particles in a manner consistent with an early role in IFT-B particle assembly. dyf-11 expression in ciliated neurons is dependent upon the presence of the DAF-19 RFX transcription factor. [Source: WormBase]
C02H7.3C02H7.3aaex-3923 XReverseView as cDNA map |
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aex-3 encodes a guanine nucleotide exchange factor for the rab-3 GTPase that is orthologous to human MAP kinase activating protein containing death domain (MADD, OMIM:603584). AEX-3 is required for intracellular vesicle trafficking as well as synaptic vesicle release and interacts with CAB-1 and RAB-3 to regulate separate pathways for neural activities such as defecation and male mating, respectively. AEX-3 is also required for egg laying and locomotion. AEX-3 is expressed in nearly all neurons. [Source: WormBase]
C03B1.12C03B1.12.1lmp-1123 XReverseView as cDNA map |
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lmp-1 encodes a protein with similarity to vertebrate lysosome-associated membrane proteins CD68, and appears to be the only protein in C. elegans that has a GYXX (phi) vertebrate lysosomal targeting sequence at its carboxy terminus. localized to the periphery of a large population of membrane bound organelles (granules) seen throughout the early embryos and restricted to the cells of the intestine during later stages. [Source: WormBase]
C03B1.12C03B1.12.2lmp-1123 XReverseView as cDNA map |
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lmp-1 encodes a protein with similarity to vertebrate lysosome-associated membrane proteins CD68, and appears to be the only protein in C. elegans that has a GYXX (phi) vertebrate lysosomal targeting sequence at its carboxy terminus. localized to the periphery of a large population of membrane bound organelles (granules) seen throughout the early embryos and restricted to the cells of the intestine during later stages. [Source: WormBase]
C03B1.13C03B1.13C03B1.13123 XReverseView as cDNA map |
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C03B1.14C03B1.14C03B1.14123 XReverseView as cDNA map |
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C03B1.5C03B1.5C03B1.5123 XForwardView as cDNA map |
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C03F11.4C03F11.4.1C03F11.4223 XReverseView as cDNA map |
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C03F11.4C03F11.4.2C03F11.4123 XReverseView as cDNA map |
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C03F11.4C03F11.4.3C03F11.4123 XReverseView as cDNA map |
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C03G5.1C03G5.1.1sdha-1123 XReverseView as cDNA map |
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sdha-1 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT A, FLAVOPROTEIN (SDHA. OMIM:600857), which when mutated leads to complex II mitochondrial respiratory chain deficiency presenting as Leigh syndrome. [Source: WormBase]
C03G5.1C03G5.1.2sdha-1123 XReverseView as cDNA map |
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sdha-1 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT A, FLAVOPROTEIN (SDHA. OMIM:600857), which when mutated leads to complex II mitochondrial respiratory chain deficiency presenting as Leigh syndrome. [Source: WormBase]
C03G5.7C03G5.7flp-5123 XForwardView as cDNA map |
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flp-5 encodes a predicted FMRFamide-like peptide neurotransmitter that increases action potential frequency in the pharyngeal muscle when applied to the pharynx of dissected worms. expressed in the sensory neurons ASE and PVM. [Source: WormBase]
C03H12.1C03H12.1C03H12.1123 XForwardView as cDNA map |
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C04A11.1C04A11.1C04A11.1123 XForwardView as cDNA map |
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C04A11.2C04A11.2C04A11.2123 XReverseView as cDNA map |
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C04A11.3C04A11.3gck-4423 XForwardView as cDNA map |
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C04A11.4C04A11.4adm-2423 XForwardView as cDNA map |
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adm-2 encodes a protein containing a snake venom disintegrin-domain and a metalloprotease-like domain (i.e., a protein of the ADAM family). like ADM-1, ADM-2 is homologous to a mammalian sperm glycoprotein (PH-30/fertilin) implicated in sperm-egg fusion, and ADM-2 might thus be a fusogenic protein mediating the merging of plasma membranes during development. [Source: WormBase]
C04A11.5C04A11.5.1C04A11.5223 XForwardView as cDNA map |
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C04A11.5C04A11.5.2C04A11.5223 XForwardView as cDNA map |
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C04B4.1C04B4.1.1C04B4.1323 XForwardView as cDNA map |
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C04B4.1C04B4.1.2C04B4.1323 XForwardView as cDNA map |
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C04B4.3C04B4.3lips-2123 XForwardView as cDNA map |
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C04B4.4C04B4.4C04B4.4123 XForwardView as cDNA map |
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C04B4.6C04B4.6C04B4.6223 XReverseView as cDNA map |
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C04C11.1C04C11.1aC04C11.1123 XForwardView as cDNA map |
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C04C11.2C04C11.2.1arrd-25123 XForwardView as cDNA map |
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C04C11.2C04C11.2.2arrd-25123 XForwardView as cDNA map |
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C04E7.1C04E7.1C04E7.1123 XForwardView as cDNA map |
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C04E7.2C04E7.2sor-3223 XForwardView as cDNA map |
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sor-3 encodes a novel protein that contains an MBT (malignant brain tumor) domain related to the MBT domains found in the Sex comb on midleg (SCM) and Sfmbt Polycomb group proteins. during development, SOR-3 activity is required to specify the correct number of dopaminergic and serotonergic neurons in males, as well as for proper ray neuron axon guidance, distal tip cell migration, and normal body size. SOR-3 activity is necessary for maintaining repression of Hox gene expression, notably that of egl-5 in many head neurons. in regulating neurotransmitter phenotype, sor-3 functions together with sop-2, which also encodes a Polycomb group protein, and members of the TGF-beta signaling pathway. sor-3 and sop-2 also function together to regulate progression through larval development. a SOR-3::GFP reporter fusion is expressed ubiquitously throughout the life cycle and localizes to both the cytoplasm and the nucleus. [Source: WormBase]
C04E7.3C04E7.3C04E7.3223 XReverseView as cDNA map |
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C04E7.4C04E7.4C04E7.4123 XReverseView as cDNA map |
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C04F6.1C04F6.1vit-5123 XForwardView as cDNA map |
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vit-5 encodes a vitellogenin, a lipid-binding protein precursor related to vertebrate vitellogenins and mammalian ApoB-100, a core LDL particle constituent. by homology, VIT-5 is predicted to function as a lipid transport protein. loss of vit-5 activity via large-scale RNA-mediated interference (RNAi) screens indicates that VIT-5 is required for embryogenesis and normal rates of postembryonic growth. VIT-5 is a major yolk component and is expressed exclusively in the adult hermaphrodite intestine from which it is secreted into the pseudocoelomic space and taken up by oocytes. [Source: WormBase]
C04F6.3C04F6.3.1cht-1123 XReverseView as cDNA map |
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cht-1 encodes a chitinase orthologous to human chitinase-1 (OMIM:600031, mutations are associated with chitotriosidase deficiency). CHT-1 is predicted to function as an extracellular O-glycosyl hydrolase that hydrolyzes the glycosidic bond between two or more carbohydrates. in C. elegans, CHT-1 may play a role in embryogenesis, and may also be required for cuticle degradation during molting and degradation of chitin-containing pathogens as part of a host defense mechanism. [Source: WormBase]
C04F6.3C04F6.3.2cht-1123 XReverseView as cDNA map |
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cht-1 encodes a chitinase orthologous to human chitinase-1 (OMIM:600031, mutations are associated with chitotriosidase deficiency). CHT-1 is predicted to function as an extracellular O-glycosyl hydrolase that hydrolyzes the glycosidic bond between two or more carbohydrates. in C. elegans, CHT-1 may play a role in embryogenesis, and may also be required for cuticle degradation during molting and degradation of chitin-containing pathogens as part of a host defense mechanism. [Source: WormBase]
C04F6.4C04F6.4aunc-78223 XReverseView as cDNA map |
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The unc-78 gene encodes a homolog of actin-interacting protein 1 (AIP1) that regulates the ordered assembly of actin and cofilin in myofibrils. [Source: WormBase]
C04F6.7C04F6.7C04F6.7123 XReverseView as cDNA map |
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C05A9.1C05A9.1apgp-5223 XReverseView as cDNA map |
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pgp-5 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily. by homology, PGP-5 is predicted to function as an ATP-dependent efflux pump that protects C. elegans by exporting exogenous toxins. however, as loss of pgp-5 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of PGP-5 in C. elegans development and/or behavior is not yet known. [Source: WormBase]
C05A9.1C05A9.1bpgp-5223 XReverseView as cDNA map |
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pgp-5 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily. by homology, PGP-5 is predicted to function as an ATP-dependent efflux pump that protects C. elegans by exporting exogenous toxins. however, as loss of pgp-5 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of PGP-5 in C. elegans development and/or behavior is not yet known. [Source: WormBase]
C05C9.3C05C9.3C05C9.3523 XReverseView as cDNA map |
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The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77). [Source: WormBase]
C05D9.2C05D9.2.1lmp-2223 XForwardView as cDNA map |
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lmp-2 encodes a transmembrane protein that is one of two C. elegans LAMP (lysosomal associated membrane glycoprotein) homologs. [Source: WormBase]
C05D9.2C05D9.2.2lmp-2223 XForwardView as cDNA map |
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lmp-2 encodes a transmembrane protein that is one of two C. elegans LAMP (lysosomal associated membrane glycoprotein) homologs. [Source: WormBase]
C05D9.2C05D9.2.3lmp-2223 XForwardView as cDNA map |
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lmp-2 encodes a transmembrane protein that is one of two C. elegans LAMP (lysosomal associated membrane glycoprotein) homologs. [Source: WormBase]
C05D9.3C05D9.3C05D9.3323 XForwardView as cDNA map |
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C05D9.4C05D9.4C05D9.4123 XForwardView as cDNA map |
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C05D9.5C05D9.5ife-4123 XForwardView as cDNA map |
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The ife-4 gene encodes a member of the Initiation Factor 4E (eIF4E) family. [Source: WormBase]
C05D9.7C05D9.7C05D9.7223 XReverseView as cDNA map |
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GUI created by the Computational Medicine Center at the Sidney Kimmel Medical College of Thomas Jefferson University
We gratefully acknowledge support of this work by the William M. Keck Foundation