| Gene ID | Transcript ID | Common Gene Name | # of miRNA targets for specified miRNAs | Chromosome | Strand Direction | Transcript Link to view miRNA target predictions | Gene Link | Description |
|---|---|---|---|---|---|---|---|---|
| B0198.2 | B0198.2a | B0198.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0198.2 | B0198.2b | B0198.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0272.4 | B0272.4 | B0272.4 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0302.1 | B0302.1a.1 | kin-25 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | kin-25 encodes a nonreceptor tyrosine kinase that is a member of the Ack subfamily of cytoplasmic tyrosine kinases. [Source: WormBase] |
| B0395.1 | B0395.1 | nhx-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | nhx-1 encodes a sodium/proton exchanger expressed intracellularly within hypodermal and muscle cells. NHX-1 is required for embryonic viability, and is thought to prevent intracellular acidification by catalysing the electroneutral exchange of vesicular sodium for an intracellular proton. [Source: WormBase] |
| B0403.5 | B0403.5 | B0403.5 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0403.6 | B0403.6 | B0403.6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| B0416.1 | B0416.1 | B0416.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0563.2 | B0563.2 | tsp-11 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0563.4 | B0563.4.1 | tmbi-4 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0563.4 | B0563.4.2 | tmbi-4 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0563.6 | B0563.6a | B0563.6 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0563.6 | B0563.6b.1 | B0563.6 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0563.6 | B0563.6b.2 | B0563.6 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0563.6 | B0563.6c | B0563.6 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C02B8.5 | C02B8.5 | C02B8.5 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | C02B8.5 encodes a homolog of the functionally active Fmrf Receptor (FR. CG2114) of D. melanogaster. it is thus possible that C02B8.5 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12). [Source: WormBase] |
| C02D4.2 | C02D4.2a | ser-2 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase] |
| C02D4.2 | C02D4.2b | ser-2 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase] |
| C02D4.2 | C02D4.2e | ser-2 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase] |
| C02D4.2 | C02D4.2f | ser-2 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase] |
| C02F12.10 | C02F12.10 | C02F12.10 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | C02F12.10 encodes a homeobox protein of uncertain affinity, but with some similarity to vertebrate Hox3 proteins and the D. melanogster homeobox protein ROUGH. C02F12.10 is expressed in a single tail neuron of hermaphrodites from late embryo to adult stages, as well as in a uterus cell separate from the vulva (perhaps in the spermetheca). C02F12.10 has no obvious function in mass RNAi assays. [Source: WormBase] |
| C02F12.4 | C02F12.4 | tag-52 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C02F12.8 | C02F12.8 | C02F12.8 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C02H7.3 | C02H7.3a | aex-3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | aex-3 encodes a guanine nucleotide exchange factor for the rab-3 GTPase that is orthologous to human MAP kinase activating protein containing death domain (MADD, OMIM:603584). AEX-3 is required for intracellular vesicle trafficking as well as synaptic vesicle release and interacts with CAB-1 and RAB-3 to regulate separate pathways for neural activities such as defecation and male mating, respectively. AEX-3 is also required for egg laying and locomotion. AEX-3 is expressed in nearly all neurons. [Source: WormBase] |
| C03A3.3 | C03A3.3 | C03A3.3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C03B1.2 | C03B1.2 | C03B1.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C03B1.7 | C03B1.7 | C03B1.7 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C03G5.1 | C03G5.1.1 | sdha-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | sdha-1 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT A, FLAVOPROTEIN (SDHA. OMIM:600857), which when mutated leads to complex II mitochondrial respiratory chain deficiency presenting as Leigh syndrome. [Source: WormBase] |
| C03G5.1 | C03G5.1.2 | sdha-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | sdha-1 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT A, FLAVOPROTEIN (SDHA. OMIM:600857), which when mutated leads to complex II mitochondrial respiratory chain deficiency presenting as Leigh syndrome. [Source: WormBase] |
| C04A11.3 | C04A11.3 | gck-4 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C04A11.4 | C04A11.4 | adm-2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | adm-2 encodes a protein containing a snake venom disintegrin-domain and a metalloprotease-like domain (i.e., a protein of the ADAM family). like ADM-1, ADM-2 is homologous to a mammalian sperm glycoprotein (PH-30/fertilin) implicated in sperm-egg fusion, and ADM-2 might thus be a fusogenic protein mediating the merging of plasma membranes during development. [Source: WormBase] |
| C04B4.2 | C04B4.2 | C04B4.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C04F6.5 | C04F6.5 | dhs-27 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | dhs-27 encodes a short-chain dehydrogenase predicted to be mitochondrial. [Source: WormBase] |
| C05A9.1 | C05A9.1a | pgp-5 | 3 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | pgp-5 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily. by homology, PGP-5 is predicted to function as an ATP-dependent efflux pump that protects C. elegans by exporting exogenous toxins. however, as loss of pgp-5 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of PGP-5 in C. elegans development and/or behavior is not yet known. [Source: WormBase] |
| C05A9.1 | C05A9.1b | pgp-5 | 3 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | pgp-5 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily. by homology, PGP-5 is predicted to function as an ATP-dependent efflux pump that protects C. elegans by exporting exogenous toxins. however, as loss of pgp-5 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of PGP-5 in C. elegans development and/or behavior is not yet known. [Source: WormBase] |
| C05C9.1 | C05C9.1 | C05C9.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C05E11.1 | C05E11.1.1 | lnp-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | lnp-1 encodes a highly conserved protein of unknown function, orthologous to human LUNAPARK/KIAA1715 (OMIM:610236), that is required for normally short body length, normal locomotion, fat content, acetylcholine neurotransmission, localization of RAB-3 and SNB-1, and sensitivity to aldicarb. LNP-1 is expressed in muscles, hypodermal cells, and neurons. within neurons, LNP-1 is localized to cell bodies, neuritic processes and commissures, and requiring UNC-104 for localization outside of cell bodies. LNP-1 is likely to act presynaptically. LNP-1 contains two N-terminal predicted transmembrane sequences, and an atypical zinc finger domain (C2HC2). [Source: WormBase] |
| C05E11.4 | C05E11.4 | amt-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | amt-1 encodes a transmembrane transporter that by homology, is predicted to transport ammonium ions across the plasma membrane. as loss of amt-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of AMT-1 in C. elegans development and/or behavior is not yet known. [Source: WormBase] |
| C05E11.5 | C05E11.5 | amt-4 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | amt-4 encodes a member of the ammonium transporter protein family. [Source: WormBase] |
| C05E11.7 | C05E11.7 | C05E11.7 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C05E11.8 | C05E11.8b | flp-12 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | flp-12 encodes a predicted FMRFamide-like peptide neurotransmitter that affects locomotion when injected into A. suum. expressed in the ASE and PVM sensory neurons. [Source: WormBase] |
| C05E7.1 | C05E7.1 | C05E7.1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C05G5.1 | C05G5.1 | C05G5.1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C05G5.5 | C05G5.5 | C05G5.5 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C06G1.4 | C06G1.4.1 | ain-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | ain-1 encodes an unfamiliar protein synergistically required, with LIN-31, for the normal timing of vulval differentiation, independently of LET-60/RAS, and parallel to or downstream of LIN-14/LIN-28/HBL-1. AIN-1 is expressed in cytoplasmic foci (that are probably P bodies) in several tissues, including vulval precursor cells and neurons. AIN-1 coimmunoprecipitates with DCR-1 and ALG-1, also binds ALG-1 in vitro, and does not require DNA or RNA for its binding. in vivo, AIN-1 targets ALG-1 to cytoplasmic foci, in which it colocalizes with DCAP-2. AIN-1 is likely to be a RISC component, since anti-AIN-1 antibodies precipitate 29 different miRNAs, including mir-2, mir-52, mir-58, mir-71, mir-77, and mir-239a. ain-1(ku322) mutants are essentially wild-type, except for sporadically gapped alae and excess seam cell nuclei arising from retarded seam cell fusion. more prominently, ain-1(ku322) suppresses the multivulva phenotype of lin-31(n1053) mutations, while strongly enhancing lin-31(n1053)'s egg-laying defect. the cellular basis of lin-31(n1053).ain-1(ku322) phenotypes is a delay in vulval development in L4 larvae not seen with either mutation alone. ain-1(ku322) has no effect on let-60(n1046) or lin-3(e1275) mutations. ain-1(ku322) suppresses the precocious vulval development of lin-14(RNAi), lin-28 mutants, and hbl-1(RNAi). alg-1 or alg-1 ain-1 mutant alae resemble ain-1 alae, indicating that ALG-1 and AIN-1 act in a common genetic pathway. AIN-1 is homologous to Brugia malayi 14748.m00068, 14052.m00191, and 14963.m01790, and paralogous to C. elegans B0041.2. AIN-1 and its nematode homologs have weak similarity to human TNRC6A (GW182. OMIM:610739) and Drosophila GAWKY. [Source: WormBase] |
| C06G1.4 | C06G1.4.2 | ain-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | ain-1 encodes an unfamiliar protein synergistically required, with LIN-31, for the normal timing of vulval differentiation, independently of LET-60/RAS, and parallel to or downstream of LIN-14/LIN-28/HBL-1. AIN-1 is expressed in cytoplasmic foci (that are probably P bodies) in several tissues, including vulval precursor cells and neurons. AIN-1 coimmunoprecipitates with DCR-1 and ALG-1, also binds ALG-1 in vitro, and does not require DNA or RNA for its binding. in vivo, AIN-1 targets ALG-1 to cytoplasmic foci, in which it colocalizes with DCAP-2. AIN-1 is likely to be a RISC component, since anti-AIN-1 antibodies precipitate 29 different miRNAs, including mir-2, mir-52, mir-58, mir-71, mir-77, and mir-239a. ain-1(ku322) mutants are essentially wild-type, except for sporadically gapped alae and excess seam cell nuclei arising from retarded seam cell fusion. more prominently, ain-1(ku322) suppresses the multivulva phenotype of lin-31(n1053) mutations, while strongly enhancing lin-31(n1053)'s egg-laying defect. the cellular basis of lin-31(n1053).ain-1(ku322) phenotypes is a delay in vulval development in L4 larvae not seen with either mutation alone. ain-1(ku322) has no effect on let-60(n1046) or lin-3(e1275) mutations. ain-1(ku322) suppresses the precocious vulval development of lin-14(RNAi), lin-28 mutants, and hbl-1(RNAi). alg-1 or alg-1 ain-1 mutant alae resemble ain-1 alae, indicating that ALG-1 and AIN-1 act in a common genetic pathway. AIN-1 is homologous to Brugia malayi 14748.m00068, 14052.m00191, and 14963.m01790, and paralogous to C. elegans B0041.2. AIN-1 and its nematode homologs have weak similarity to human TNRC6A (GW182. OMIM:610739) and Drosophila GAWKY. [Source: WormBase] |
| C06G1.5 | C06G1.5 | C06G1.5 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C07A4.1 | C07A4.1 | tiar-3 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C07B5.4 | C07B5.4a.1 | C07B5.4 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C07B5.4 | C07B5.4a.2 | C07B5.4 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C07B5.4 | C07B5.4b.1 | C07B5.4 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C07B5.4 | C07B5.4b.2 | C07B5.4 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C08A9.1 | C08A9.1 | sod-3 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | sod-3 encodes a iron/manganese superoxide dismutase, predicted to be mitochondrial, that might defend against oxidative stress and promote normal lifespan. sod-3 mRNA levels are diminished by mutation of daf-16 and chromatin immunoprecipitation (ChIP) studies demonstrate that DAF-16 can directly bind the sod-3 promoter. heterologously expressed SOD-3 in E. coli protects against methyl viologen-induced oxidative stress. [Source: WormBase] |
| C08A9.3 | C08A9.3a | C08A9.3 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C08A9.3 | C08A9.3b | C08A9.3 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C08A9.6 | C08A9.6 | C08A9.6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C08A9.8 | C08A9.8 | C08A9.8 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C08A9.9 | C08A9.9.1 | C08A9.9 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C08A9.9 | C08A9.9.2 | C08A9.9 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C09B8.1 | C09B8.1 | ipp-5 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | ipp-5 encodes a type I inositol 5-phosphatase homolog. ipp-5 acts downstream of let-23 to negatively regulate IP3 signaling and is involved in spermathecal contractions during ovulation. an ipp-5::gfp transcriptional reporter is expressed in the adult distal spermatheca and weakly in the proximal sheath. [Source: WormBase] |
| C09B8.5 | C09B8.5 | C09B8.5 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C09B8.7 | C09B8.7a.1 | pak-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | pak-1 encodes, by alternative splicing, at least five isoforms of a putative p21-activated kinase orthologous to human PAK1, PAK2 (OMIM:?), and PAK3 (OMIM:300142, mutated in nonsyndromic mental retardation). PAK-1 is required (redundantly with its paralog, MAX-2) for normal axonal guidance of motoneurons, P cell migration, and locomotion, with max-2(cy2).pak-1(ok448) double mutants phenotypically resembling unc-73 or ced-10.mig-2 mutants. pak-1 is expressed in pharyngeal muscles, CAN neurons, ventral cord motoneurons, migrating distal tip cells, developing uterus, B, Y, and T cells in the male tail, and vulval muscle cells. by itself, the null pak-1(ok448) mutation has no known phenotype. [Source: WormBase] |
| C09B8.7 | C09B8.7a.2 | pak-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | pak-1 encodes, by alternative splicing, at least five isoforms of a putative p21-activated kinase orthologous to human PAK1, PAK2 (OMIM:?), and PAK3 (OMIM:300142, mutated in nonsyndromic mental retardation). PAK-1 is required (redundantly with its paralog, MAX-2) for normal axonal guidance of motoneurons, P cell migration, and locomotion, with max-2(cy2).pak-1(ok448) double mutants phenotypically resembling unc-73 or ced-10.mig-2 mutants. pak-1 is expressed in pharyngeal muscles, CAN neurons, ventral cord motoneurons, migrating distal tip cells, developing uterus, B, Y, and T cells in the male tail, and vulval muscle cells. by itself, the null pak-1(ok448) mutation has no known phenotype. [Source: WormBase] |
| C09C7.1 | C09C7.1 | zig-4 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | zig-4 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins. ZIG-4 activity is required for maintenance of ventral nerve cord organization: the AVKL/R and PVQL/R axons of the left and right ventral nerve cords do not maintain their proper spatial positions and drift into the opposite cord. a zig-4::gfp reporter fusion is expressed in the PVT, ASK, BAG, and M2 neurons, with expression also seen during the L1 stage in pharyngeal mesoderm and ectoderm. [Source: WormBase] |
| C09F12.1 | C09F12.1.1 | clc-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | clc-1 encodes a claudin homolog, closely similar to CLC-2, that is required for normal cohesion of apical junctions in epithelia. claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water. CLC-1 maintains the impermeability ('barrier function') of epithelia, since clc-1(RNAi) animals have abnormal permeability of the pharynx to dyes. clc-1 is expressed in spermatheca, pharynx, intestine, hypodermis, the excretory-secretory system, and the cell-cell junctions of the vulva. in pharyngeal cells, CLC-1 colocalizes with AJM-1 in long thin lines, parallel to the pharyngeal axis and lining the lumenal surface, that appear to correspond with apical intercellular junctions. [Source: WormBase] |
| C09F12.1 | C09F12.1.2 | clc-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | clc-1 encodes a claudin homolog, closely similar to CLC-2, that is required for normal cohesion of apical junctions in epithelia. claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water. CLC-1 maintains the impermeability ('barrier function') of epithelia, since clc-1(RNAi) animals have abnormal permeability of the pharynx to dyes. clc-1 is expressed in spermatheca, pharynx, intestine, hypodermis, the excretory-secretory system, and the cell-cell junctions of the vulva. in pharyngeal cells, CLC-1 colocalizes with AJM-1 in long thin lines, parallel to the pharyngeal axis and lining the lumenal surface, that appear to correspond with apical intercellular junctions. [Source: WormBase] |
| C09F12.2 | C09F12.2 | C09F12.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C09G1.4 | C09G1.4 | C09G1.4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C10A4.2 | C10A4.2 | C10A4.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C10A4.6 | C10A4.6 | C10A4.6 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C10A4.9 | C10A4.9 | C10A4.9 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C10E2.3 | C10E2.3 | hda-4 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | hda-4 encodes a class II histone deacetylase that contains a putative MEF-2 DNA binding domain, a nuclear localization signal domain, and a single catalytic domain and may affect locomotion, body morphology, and growth. interacts with MEF-2 in in vitro assays and is expressed in body-wall muscle, neurons, and hypodermal seam cells [Source: WormBase] |
| C10E2.6 | C10E2.6.1 | C10E2.6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C10E2.6 | C10E2.6.2 | C10E2.6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C11E4.6 | C11E4.6.1 | C11E4.6 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C11E4.6 | C11E4.6.2 | C11E4.6 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C11G6.4 | C11G6.4a | nhr-28 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C11H1.4 | C11H1.4a | prx-1 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | prx-1 encodes a predicted peroxin, a subfamily 2 member of the AAA (ATPases Associated with diverse cellular Activities) family that affects growth in one large-scale RNAi screen. expressed in intestinal cells throughout development. [Source: WormBase] |
| C11H1.4 | C11H1.4b | prx-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | prx-1 encodes a predicted peroxin, a subfamily 2 member of the AAA (ATPases Associated with diverse cellular Activities) family that affects growth in one large-scale RNAi screen. expressed in intestinal cells throughout development. [Source: WormBase] |
| C11H1.9 | C11H1.9a | C11H1.9 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C11H1.9 | C11H1.9b | C11H1.9 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C12D12.1 | C12D12.1a | C12D12.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C12D12.1 | C12D12.1b | C12D12.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C12D12.1 | C12D12.1c | C12D12.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C13E3.1 | C13E3.1 | C13E3.1 | 3 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C14E2.2 | C14E2.2 | C14E2.2 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C14E2.6 | C14E2.6 | C14E2.6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C14F11.4 | C14F11.4a | C14F11.4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C14F11.4 | C14F11.4b | C14F11.4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C14F5.3 | C14F5.3b | tnt-3 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | tnt-3 is orthologous to the human gene TROPONIN T (TNNT2. OMIM:191045), which when mutated leads to disease. [Source: WormBase] |
| C14F5.3 | C14F5.3d | tnt-3 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | tnt-3 is orthologous to the human gene TROPONIN T (TNNT2. OMIM:191045), which when mutated leads to disease. [Source: WormBase] |
| C15A7.2 | C15A7.2 | C15A7.2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C15B12.2 | C15B12.2.1 | C15B12.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C15B12.2 | C15B12.2.2 | C15B12.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C15B12.8 | C15B12.8 | C15B12.8 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C15C7.2 | C15C7.2.1 | klp-8 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | klp-8 encodes an atypical kinesin-like motor protein with the motor domain in the N-terminus. the motor domain of KLP-8 exhibits poor homology to the globular motor domain of the kinesin heavy chain. [Source: WormBase] |
| C15C7.2 | C15C7.2.2 | klp-8 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | klp-8 encodes an atypical kinesin-like motor protein with the motor domain in the N-terminus. the motor domain of KLP-8 exhibits poor homology to the globular motor domain of the kinesin heavy chain. [Source: WormBase] |
| C15C7.6 | C15C7.6 | C15C7.6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C15H9.1 | C15H9.1 | nnt-1 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | nnt-1 encodes a proton-pumping nicotinamide nucleotide transhydrogenase predicted to be mitochondrial. [Source: WormBase] |
| C16B8.3 | C16B8.3 | C16B8.3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl |