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Genome: Caenorhabditis Elegans | mRNA | miRBase 18 (Nov. 2011), ENSEMBL 65 (Dec. 2011) and RNA22v1.0
Description: List of transcripts that are targeted by all of the below miRNA identifiers simultaneously
miRNA's: cel-miR-4937 (MIMAT0020143)
Filtering By: Base pair min value: 12 | Folding energy max value (Kcal/mol): -21 | Min miRNA targets: 1


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Gene IDTranscript IDCommon Gene Name# of miRNA targets
for specified miRNAs
ChromosomeStrand DirectionTranscript Link to view miRNA target predictionsGene LinkDescription
AC8.10AC8.10AC8.10223 XReverseView as cDNA map |
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Ensembl
AC8.11AC8.11AC8.11123 XReverseView as cDNA map |
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Ensembl
AC8.3AC8.3AC8.3223 XReverseView as cDNA map |
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Ensembl
AC8.4AC8.4AC8.4123 XReverseView as cDNA map |
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Ensembl
AH9.1AH9.1AH9.1123 XReverseView as cDNA map |
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Ensembl
AH9.6AH9.6AH9.6123 XReverseView as cDNA map |
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Ensembl
AH9.6 encodes a novel protein that contains two predicted transmembrane domains and that is conserved in other nematode species. [Source: WormBase]
B0198.1B0198.1tsp-20323 XReverseView as cDNA map |
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Ensembl
B0198.2B0198.2aB0198.2223 XForwardView as cDNA map |
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Ensembl
B0198.2B0198.2bB0198.2223 XForwardView as cDNA map |
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Ensembl
B0198.3B0198.3aB0198.3723 XReverseView as cDNA map |
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Ensembl
B0272.1B0272.1tbb-4323 XReverseView as cDNA map |
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Ensembl
B0272.3B0272.3.1B0272.3223 XForwardView as cDNA map |
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Ensembl
B0272.3 encodes a 3-hydroxyacyl-CoA dehydrogenase. by homology, the product of B0272.3 is predicted to function in mitochondrial fatty acid metabolism by catalyzing the NAD+-dependent oxidation of short-chain hydroxyacyl CoAs. large-scale expression studies indicate that B0272.3 is widely expressed. [Source: WormBase]
B0272.3B0272.3.2B0272.3223 XForwardView as cDNA map |
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Ensembl
B0272.3 encodes a 3-hydroxyacyl-CoA dehydrogenase. by homology, the product of B0272.3 is predicted to function in mitochondrial fatty acid metabolism by catalyzing the NAD+-dependent oxidation of short-chain hydroxyacyl CoAs. large-scale expression studies indicate that B0272.3 is widely expressed. [Source: WormBase]
B0294.3B0294.3B0294.3123 XForwardView as cDNA map |
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Ensembl
This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins. [Source: WormBase]
B0302.1B0302.1a.1kin-25623 XForwardView as cDNA map |
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Ensembl
kin-25 encodes a nonreceptor tyrosine kinase that is a member of the Ack subfamily of cytoplasmic tyrosine kinases. [Source: WormBase]
B0302.1B0302.1a.2kin-25423 XForwardView as cDNA map |
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Ensembl
kin-25 encodes a nonreceptor tyrosine kinase that is a member of the Ack subfamily of cytoplasmic tyrosine kinases. [Source: WormBase]
B0302.1B0302.1bkin-25223 XForwardView as cDNA map |
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Ensembl
kin-25 encodes a nonreceptor tyrosine kinase that is a member of the Ack subfamily of cytoplasmic tyrosine kinases. [Source: WormBase]
B0302.5B0302.5B0302.5223 XReverseView as cDNA map |
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Ensembl
B0310.2B0310.2.1B0310.2323 XReverseView as cDNA map |
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B0310.2B0310.2.2B0310.2323 XReverseView as cDNA map |
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B0310.3B0310.3B0310.3123 XReverseView as cDNA map |
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Ensembl
B0310.5B0310.5ugt-46323 XReverseView as cDNA map |
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B0310.6B0310.6B0310.6123 XReverseView as cDNA map |
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Ensembl
B0344.2B0344.2wrt-9223 XForwardView as cDNA map |
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Ensembl
wrt-9 encodes a hedgehog-like protein, with an N-terminal signal sequence, a Wart domain, and a C-terminal region of proline-rich, low-complexity sequence. the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins. WRT-9 has no obvious function in RNAi assays. [Source: WormBase]
B0395.1B0395.1nhx-1223 XForwardView as cDNA map |
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nhx-1 encodes a sodium/proton exchanger expressed intracellularly within hypodermal and muscle cells. NHX-1 is required for embryonic viability, and is thought to prevent intracellular acidification by catalysing the electroneutral exchange of vesicular sodium for an intracellular proton. [Source: WormBase]
B0395.2B0395.2mboa-1123 XForwardView as cDNA map |
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mboa-1 encodes a putative acyl-Coenzyme A:cholesterol ('sterol') O-acyltransferase, orthologous to human SOAT1 (OMIM:102642). MBOA-1 is required for normal locomotion and normally long lifespan in mass RNAi assays. mboa-1 is expressed in the seam cells and nervous systems of larvae and adults, and in the adult reproductive system. [Source: WormBase]
B0395.3B0395.3.1B0395.3223 XReverseView as cDNA map |
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B0395.3 is orthologous to the human gene CHOLINE ACETYLTRANSFERASE ISOFORM R (CHAT. OMIM:118490), which when mutated leads to disease. [Source: WormBase]
B0395.3B0395.3.2B0395.3223 XReverseView as cDNA map |
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B0395.3 is orthologous to the human gene CHOLINE ACETYLTRANSFERASE ISOFORM R (CHAT. OMIM:118490), which when mutated leads to disease. [Source: WormBase]
B0403.2B0403.2ubc-17423 XForwardView as cDNA map |
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B0403.4B0403.4tag-320623 XReverseView as cDNA map |
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B0403.5B0403.5B0403.5123 XForwardView as cDNA map |
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B0403.6B0403.6B0403.6223 XReverseView as cDNA map |
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B0410.2B0410.2avang-1323 XForwardView as cDNA map |
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vang-1 encodes an ortholog of Drosophila VAN GOGH (also known as STRABISMUS). VANG-1 enables Wnt-directed planar cell polarity. VANG-1 is required for the fully asymmetrical division of B.a versus B.p cells, though this requirement is quantitatively weak. [Source: WormBase]
B0410.2B0410.2bvang-1323 XForwardView as cDNA map |
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vang-1 encodes an ortholog of Drosophila VAN GOGH (also known as STRABISMUS). VANG-1 enables Wnt-directed planar cell polarity. VANG-1 is required for the fully asymmetrical division of B.a versus B.p cells, though this requirement is quantitatively weak. [Source: WormBase]
B0410.3B0410.3B0410.3123 XReverseView as cDNA map |
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B0416.1B0416.1B0416.1623 XForwardView as cDNA map |
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B0416.2B0416.2B0416.2123 XForwardView as cDNA map |
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B0416.5B0416.5aB0416.5223 XReverseView as cDNA map |
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B0416.5B0416.5bB0416.5223 XReverseView as cDNA map |
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B0416.6B0416.6gly-13123 XReverseView as cDNA map |
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gly-13 encodes an experimentally verified UDP-N-acetylglucosamine alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I (GnT I), that is the primary GnT I enzyme in vivo, and that can act on unusual substrates. gly-13 is expressed throughout development in many cell types. gly-13 has no obvious function in vivo, since a deletion allele of gly-13 is phenotypically normal even as a double or triple mutant with gly-12 and gly-14. [Source: WormBase]
B0563.10B0563.10B0563.10123 XReverseView as cDNA map |
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B0563.1B0563.1B0563.1323 XForwardView as cDNA map |
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B0563.2B0563.2tsp-11123 XForwardView as cDNA map |
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B0563.5B0563.5B0563.5123 XForwardView as cDNA map |
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B0563.6B0563.6aB0563.6523 XForwardView as cDNA map |
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B0563.6B0563.6b.1B0563.6523 XForwardView as cDNA map |
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B0563.6B0563.6b.2B0563.6423 XForwardView as cDNA map |
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B0563.6B0563.6cB0563.6323 XForwardView as cDNA map |
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B0563.8B0563.8B0563.8123 XReverseView as cDNA map |
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C01C10.1C01C10.1clc-2123 XForwardView as cDNA map |
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clc-2 encodes a claudin homolog, closely similar to CLC-1, that is required for normal cohesion of apical junctions in epithelia. claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water. CLC-2 maintains the impermeability ('barrier function') of epithelia, since clc-1(RNAi) animals have abnormal permeability of the hypodermis to dyes. clc-2 is expressed in hypodermal seam cells, with two diffuse lines of CLC-2 protein. [Source: WormBase]
C01C10.3C01C10.3.1acl-12323 XReverseView as cDNA map |
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C01C10.3C01C10.3.2acl-12223 XReverseView as cDNA map |
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C01C10.4C01C10.4clc-5123 XForwardView as cDNA map |
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clc-5 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia. CLC-5 is worm-specific, with obvious homologs only in C. elegans. CLC-5 has no obvious function in mass RNAi assays. claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water. [Source: WormBase]
C01C4.1C01C4.1nlp-1323 XForwardView as cDNA map |
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nlp-1 encodes a predicted neuropeptide-like protein of the MSFamide family with similarity to Aplysia californica (sea hare) buccalin, a neuropeptide that regulates acetylcholine-induced muscle contraction. NLP-1 is expressed in the phasmid PHB tail sensory neuron, lateral neurons, head neurons, and the intestine. the precise role of NLP-1 in nervous system function and development is not yet known. [Source: WormBase]
C01C4.2C01C4.2C01C4.2123 XForwardView as cDNA map |
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C01C4.3C01C4.3bC01C4.3423 XForwardView as cDNA map |
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C01C4.3 encodes a serine/threonine protein kinase. [Source: WormBase]
C02B4.1C02B4.1adt-1923 XForwardView as cDNA map |
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The adt-1 gene encodes a metalloproteinase with disintegrin-like and metalloproteinase with thrombospondin type I motifs (ADAMTS) that is required for male tail morphogenesis. [Source: WormBase]
C02B4.2C02B4.2nhr-17223 XReverseView as cDNA map |
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Ensembl
nhr-17 encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators. nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain. [Source: WormBase]
C02B8.1C02B8.1.1C02B8.1223 XForwardView as cDNA map |
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C02B8.1C02B8.1.2C02B8.1123 XForwardView as cDNA map |
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C02B8.5C02B8.5C02B8.5323 XReverseView as cDNA map |
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C02B8.5 encodes a homolog of the functionally active Fmrf Receptor (FR. CG2114) of D. melanogaster. it is thus possible that C02B8.5 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12). [Source: WormBase]
C02B8.6C02B8.6C02B8.6323 XReverseView as cDNA map |
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C02C6.1C02C6.1adyn-1423 XForwardView as cDNA map |
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dyn-1 encodes the C. elegans ortholog of the dynamin GTPase. dyn-1 activity is required for endocytosis, synaptic vesicle recycling, cytokinesis, and the CED-1 pathway that regulates engulfment and degradation of apoptotic cells. mutations in dyn-1 affect locomotion, egg-laying, defecation, and embryonic development, indicating that dyn-1's endocytic function is required for a number of diverse processes. dyn-1 reporter fusion constructs are expressed in motor neurons, intestinal cells, and pharyngeal muscle. [Source: WormBase]
C02C6.1C02C6.1bdyn-1523 XForwardView as cDNA map |
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dyn-1 encodes the C. elegans ortholog of the dynamin GTPase. dyn-1 activity is required for endocytosis, synaptic vesicle recycling, cytokinesis, and the CED-1 pathway that regulates engulfment and degradation of apoptotic cells. mutations in dyn-1 affect locomotion, egg-laying, defecation, and embryonic development, indicating that dyn-1's endocytic function is required for a number of diverse processes. dyn-1 reporter fusion constructs are expressed in motor neurons, intestinal cells, and pharyngeal muscle. [Source: WormBase]
C02C6.2C02C6.2aolrn-1123 XForwardView as cDNA map |
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olrn-1 encodes, by alternative splicing, two isoforms of a transmembrane protein required for differentiation of the AWC[ON] neuron, expression of str-2 in AWC[ON], adaptation to benzaldehyde, chemotaxis to butanone, and enhancement of chemotaxis to butanone by the presence of food. OLRN-1 is orthologous to Drosophila melanogaster RAW and Schistosoma japonicum SJCHGC05616. while OLRN-1 has orthologs in nematodes, trematodes, and arthropods, its has no obvious chordate homologs. OLRN-6 is expressed in many pharyngeal neurons and some head neurons, but is required solely in the AWC[ON] neuron for butanone enhancement. OLRN-6's function in butanone enhancement is both serotonin- and dopamine-independent, and appears to also act in chemotactic enhancement of 2,3-pentanedione and isoamyl alcohol. by orthology with RAW, OLRN-6 is predicted to inhibit JNK-1 signalling, which may in turn allow the asymmetrical AWC[ON] fate to emerge. [Source: WormBase]
C02C6.2C02C6.2bolrn-1123 XForwardView as cDNA map |
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olrn-1 encodes, by alternative splicing, two isoforms of a transmembrane protein required for differentiation of the AWC[ON] neuron, expression of str-2 in AWC[ON], adaptation to benzaldehyde, chemotaxis to butanone, and enhancement of chemotaxis to butanone by the presence of food. OLRN-1 is orthologous to Drosophila melanogaster RAW and Schistosoma japonicum SJCHGC05616. while OLRN-1 has orthologs in nematodes, trematodes, and arthropods, its has no obvious chordate homologs. OLRN-6 is expressed in many pharyngeal neurons and some head neurons, but is required solely in the AWC[ON] neuron for butanone enhancement. OLRN-6's function in butanone enhancement is both serotonin- and dopamine-independent, and appears to also act in chemotactic enhancement of 2,3-pentanedione and isoamyl alcohol. by orthology with RAW, OLRN-6 is predicted to inhibit JNK-1 signalling, which may in turn allow the asymmetrical AWC[ON] fate to emerge. [Source: WormBase]
C02C6.3C02C6.3aC02C6.3323 XReverseView as cDNA map |
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C02C6.3C02C6.3bC02C6.3223 XReverseView as cDNA map |
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C02D4.1C02D4.1jud-4323 XForwardView as cDNA map |
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jud-4 encodes an unfamiliar protein, putatively secreted, that is required both for normal sensitivity to ethanol and for survival after freezing and thawing. JUD-4 is expressed in hypodermis and vulval muscles. JUD-4 is orthologous to Brugia malayi Bm1_40315, but lacks obvious orthologies to non-nematode proteins. JUD-4's C-terminal domain has possible similarity to F40E10.5, and to proteins such as human HOMER1. jud-4(ys18) mutants show delayed sensitivity to ethanol levels that rapidly paralyze normal worms, but do not survive freezing and rethawing as does wild-type. JUD-4 has no obvious function in mass RNAi assays. [Source: WormBase]
C02D4.2C02D4.2aser-2223 XReverseView as cDNA map |
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ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase]
C02D4.2C02D4.2bser-2223 XReverseView as cDNA map |
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ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase]
C02D4.2C02D4.2eser-2223 XReverseView as cDNA map |
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ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase]
C02D4.2C02D4.2fser-2323 XReverseView as cDNA map |
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ser-2 encodes at least four tyramine 7-transmembrane domain receptors (GPCRs), by alternative splicing from three different promoters, that have distinct but partially overlapping expression patterns. ser-2 has at least three alternative promoters that drive SER-2 expression in a set of sensory, inter- and motor neurons (e.g., AIY, AIZ, and RIA) adding up to ~10% of all neurons in the nervous system, as well as pharyngeal cells and head muscles. the deletion ser-2(pk1397) has no obvious mutant phenotype. LIM-4 is required for SER-2 expression, and MAB-23 is required for SER-2 expression at normally high levels. [Source: WormBase]
C02F12.10C02F12.10C02F12.10123 XReverseView as cDNA map |
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C02F12.10 encodes a homeobox protein of uncertain affinity, but with some similarity to vertebrate Hox3 proteins and the D. melanogster homeobox protein ROUGH. C02F12.10 is expressed in a single tail neuron of hermaphrodites from late embryo to adult stages, as well as in a uterus cell separate from the vulva (perhaps in the spermetheca). C02F12.10 has no obvious function in mass RNAi assays. [Source: WormBase]
C02F12.1C02F12.1atsp-17223 XForwardView as cDNA map |
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C02F12.1C02F12.1btsp-17223 XForwardView as cDNA map |
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C02F12.3C02F12.3.1C02F12.3223 XReverseView as cDNA map |
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C02F12.3C02F12.3.2C02F12.3123 XReverseView as cDNA map |
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C02F12.3C02F12.3.3C02F12.3123 XReverseView as cDNA map |
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C02F12.4C02F12.4tag-52323 XReverseView as cDNA map |
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C02F12.7C02F12.7tag-278323 XReverseView as cDNA map |
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C02F12.8C02F12.8C02F12.8523 XReverseView as cDNA map |
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C02F12.9C02F12.9C02F12.9323 XForwardView as cDNA map |
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C02H7.2C02H7.2npr-19323 XReverseView as cDNA map |
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C02H7.3C02H7.3aaex-3823 XReverseView as cDNA map |
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aex-3 encodes a guanine nucleotide exchange factor for the rab-3 GTPase that is orthologous to human MAP kinase activating protein containing death domain (MADD, OMIM:603584). AEX-3 is required for intracellular vesicle trafficking as well as synaptic vesicle release and interacts with CAB-1 and RAB-3 to regulate separate pathways for neural activities such as defecation and male mating, respectively. AEX-3 is also required for egg laying and locomotion. AEX-3 is expressed in nearly all neurons. [Source: WormBase]
C03A3.1C03A3.1aC03A3.1223 XForwardView as cDNA map |
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C03A3.1C03A3.1bC03A3.1223 XForwardView as cDNA map |
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C03A3.2C03A3.2.1C03A3.2223 XForwardView as cDNA map |
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C03A3.2C03A3.2.2C03A3.2123 XForwardView as cDNA map |
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C03A3.3C03A3.3C03A3.3123 XReverseView as cDNA map |
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C03B1.12C03B1.12.1lmp-1223 XReverseView as cDNA map |
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lmp-1 encodes a protein with similarity to vertebrate lysosome-associated membrane proteins CD68, and appears to be the only protein in C. elegans that has a GYXX (phi) vertebrate lysosomal targeting sequence at its carboxy terminus. localized to the periphery of a large population of membrane bound organelles (granules) seen throughout the early embryos and restricted to the cells of the intestine during later stages. [Source: WormBase]
C03B1.12C03B1.12.2lmp-1123 XReverseView as cDNA map |
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lmp-1 encodes a protein with similarity to vertebrate lysosome-associated membrane proteins CD68, and appears to be the only protein in C. elegans that has a GYXX (phi) vertebrate lysosomal targeting sequence at its carboxy terminus. localized to the periphery of a large population of membrane bound organelles (granules) seen throughout the early embryos and restricted to the cells of the intestine during later stages. [Source: WormBase]
C03B1.13C03B1.13C03B1.13623 XReverseView as cDNA map |
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C03B1.1C03B1.1C03B1.1123 XForwardView as cDNA map |
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C03B1.2C03B1.2C03B1.2423 XForwardView as cDNA map |
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C03B1.3C03B1.3C03B1.3223 XForwardView as cDNA map |
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C03B1.4C03B1.4C03B1.4323 XForwardView as cDNA map |
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C03B1.5C03B1.5C03B1.5523 XForwardView as cDNA map |
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C03B1.6C03B1.6bC03B1.6323 XForwardView as cDNA map |
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C03B1.7C03B1.7C03B1.7523 XForwardView as cDNA map |
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We gratefully acknowledge support of this work by the William M. Keck Foundation