| Gene ID | Transcript ID | Common Gene Name | # of miRNA targets for specified miRNAs | Chromosome | Strand Direction | Transcript Link to view miRNA target predictions | Gene Link | Description |
|---|---|---|---|---|---|---|---|---|
| AH9.4 | AH9.4 | AH9.4 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| B0198.2 | B0198.2a | B0198.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0198.3 | B0198.3a | B0198.3 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| B0272.4 | B0272.4 | B0272.4 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0302.1 | B0302.1a.1 | kin-25 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | kin-25 encodes a nonreceptor tyrosine kinase that is a member of the Ack subfamily of cytoplasmic tyrosine kinases. [Source: WormBase] |
| B0302.1 | B0302.1a.2 | kin-25 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | kin-25 encodes a nonreceptor tyrosine kinase that is a member of the Ack subfamily of cytoplasmic tyrosine kinases. [Source: WormBase] |
| B0302.1 | B0302.1b | kin-25 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | kin-25 encodes a nonreceptor tyrosine kinase that is a member of the Ack subfamily of cytoplasmic tyrosine kinases. [Source: WormBase] |
| B0344.2 | B0344.2 | wrt-9 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | wrt-9 encodes a hedgehog-like protein, with an N-terminal signal sequence, a Wart domain, and a C-terminal region of proline-rich, low-complexity sequence. the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins. WRT-9 has no obvious function in RNAi assays. [Source: WormBase] |
| B0395.2 | B0395.2 | mboa-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | mboa-1 encodes a putative acyl-Coenzyme A:cholesterol ('sterol') O-acyltransferase, orthologous to human SOAT1 (OMIM:102642). MBOA-1 is required for normal locomotion and normally long lifespan in mass RNAi assays. mboa-1 is expressed in the seam cells and nervous systems of larvae and adults, and in the adult reproductive system. [Source: WormBase] |
| B0395.3 | B0395.3.1 | B0395.3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | B0395.3 is orthologous to the human gene CHOLINE ACETYLTRANSFERASE ISOFORM R (CHAT. OMIM:118490), which when mutated leads to disease. [Source: WormBase] |
| B0395.3 | B0395.3.2 | B0395.3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | B0395.3 is orthologous to the human gene CHOLINE ACETYLTRANSFERASE ISOFORM R (CHAT. OMIM:118490), which when mutated leads to disease. [Source: WormBase] |
| B0403.4 | B0403.4 | tag-320 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| B0403.5 | B0403.5 | B0403.5 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0410.3 | B0410.3 | B0410.3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| B0416.3 | B0416.3 | B0416.3 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0416.6 | B0416.6 | gly-13 | 3 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | gly-13 encodes an experimentally verified UDP-N-acetylglucosamine alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I (GnT I), that is the primary GnT I enzyme in vivo, and that can act on unusual substrates. gly-13 is expressed throughout development in many cell types. gly-13 has no obvious function in vivo, since a deletion allele of gly-13 is phenotypically normal even as a double or triple mutant with gly-12 and gly-14. [Source: WormBase] |
| B0563.4 | B0563.4.1 | tmbi-4 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0563.4 | B0563.4.2 | tmbi-4 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0563.6 | B0563.6a | B0563.6 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0563.6 | B0563.6b.1 | B0563.6 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0563.6 | B0563.6b.2 | B0563.6 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| B0563.6 | B0563.6c | B0563.6 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C01C10.2 | C01C10.2b | C01C10.2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C01C10.3 | C01C10.3.1 | acl-12 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C01C10.3 | C01C10.3.2 | acl-12 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C02B4.1 | C02B4.1 | adt-1 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | The adt-1 gene encodes a metalloproteinase with disintegrin-like and metalloproteinase with thrombospondin type I motifs (ADAMTS) that is required for male tail morphogenesis. [Source: WormBase] |
| C02C6.3 | C02C6.3a | C02C6.3 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C02C6.3 | C02C6.3b | C02C6.3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C02F12.10 | C02F12.10 | C02F12.10 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | C02F12.10 encodes a homeobox protein of uncertain affinity, but with some similarity to vertebrate Hox3 proteins and the D. melanogster homeobox protein ROUGH. C02F12.10 is expressed in a single tail neuron of hermaphrodites from late embryo to adult stages, as well as in a uterus cell separate from the vulva (perhaps in the spermetheca). C02F12.10 has no obvious function in mass RNAi assays. [Source: WormBase] |
| C02H7.2 | C02H7.2 | npr-19 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C03A3.2 | C03A3.2.1 | C03A3.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C03A3.2 | C03A3.2.2 | C03A3.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C03A3.3 | C03A3.3 | C03A3.3 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C03B1.6 | C03B1.6b | C03B1.6 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C03B1.9 | C03B1.9 | C03B1.9 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C03G5.1 | C03G5.1.1 | sdha-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | sdha-1 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT A, FLAVOPROTEIN (SDHA. OMIM:600857), which when mutated leads to complex II mitochondrial respiratory chain deficiency presenting as Leigh syndrome. [Source: WormBase] |
| C03G5.1 | C03G5.1.2 | sdha-1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | sdha-1 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT A, FLAVOPROTEIN (SDHA. OMIM:600857), which when mutated leads to complex II mitochondrial respiratory chain deficiency presenting as Leigh syndrome. [Source: WormBase] |
| C03G5.7 | C03G5.7 | flp-5 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | flp-5 encodes a predicted FMRFamide-like peptide neurotransmitter that increases action potential frequency in the pharyngeal muscle when applied to the pharynx of dissected worms. expressed in the sensory neurons ASE and PVM. [Source: WormBase] |
| C04A11.3 | C04A11.3 | gck-4 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C04A11.4 | C04A11.4 | adm-2 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | adm-2 encodes a protein containing a snake venom disintegrin-domain and a metalloprotease-like domain (i.e., a protein of the ADAM family). like ADM-1, ADM-2 is homologous to a mammalian sperm glycoprotein (PH-30/fertilin) implicated in sperm-egg fusion, and ADM-2 might thus be a fusogenic protein mediating the merging of plasma membranes during development. [Source: WormBase] |
| C04B4.2 | C04B4.2 | C04B4.2 | 3 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C04B4.3 | C04B4.3 | lips-2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C04C11.1 | C04C11.1a | C04C11.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C04E7.1 | C04E7.1 | C04E7.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C04F6.1 | C04F6.1 | vit-5 | 3 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | vit-5 encodes a vitellogenin, a lipid-binding protein precursor related to vertebrate vitellogenins and mammalian ApoB-100, a core LDL particle constituent. by homology, VIT-5 is predicted to function as a lipid transport protein. loss of vit-5 activity via large-scale RNA-mediated interference (RNAi) screens indicates that VIT-5 is required for embryogenesis and normal rates of postembryonic growth. VIT-5 is a major yolk component and is expressed exclusively in the adult hermaphrodite intestine from which it is secreted into the pseudocoelomic space and taken up by oocytes. [Source: WormBase] |
| C04F6.5 | C04F6.5 | dhs-27 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | dhs-27 encodes a short-chain dehydrogenase predicted to be mitochondrial. [Source: WormBase] |
| C05A9.1 | C05A9.1a | pgp-5 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | pgp-5 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily. by homology, PGP-5 is predicted to function as an ATP-dependent efflux pump that protects C. elegans by exporting exogenous toxins. however, as loss of pgp-5 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of PGP-5 in C. elegans development and/or behavior is not yet known. [Source: WormBase] |
| C05A9.1 | C05A9.1b | pgp-5 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | pgp-5 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily. by homology, PGP-5 is predicted to function as an ATP-dependent efflux pump that protects C. elegans by exporting exogenous toxins. however, as loss of pgp-5 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of PGP-5 in C. elegans development and/or behavior is not yet known. [Source: WormBase] |
| C05C9.3 | C05C9.3 | C05C9.3 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77). [Source: WormBase] |
| C05D9.1 | C05D9.1.1 | snx-1 | 3 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C05D9.1 | C05D9.1.2 | snx-1 | 3 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C05D9.1 | C05D9.1.3 | snx-1 | 3 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C05E7.2 | C05E7.2 | C05E7.2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C05G5.5 | C05G5.5 | C05G5.5 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C06E2.1 | C06E2.1 | C06E2.1 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C06E2.2 | C06E2.2 | C06E2.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C06E2.8 | C06E2.8 | ins-9 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | ins-9 encodes an insulin-like peptide of the insulin superfamily of proteins (OMIM:176730, 147440). INS-9 is one of 38 insulin-like peptides in C. elegans and although INS-9 overexpression can result in low levels of embryonic and larval lethality, the precise role of INS-9 in C. elegans development is not yet clear. INS-9 is expressed exclusively in the amphid sensory neurons ASI and ASJ that regulate dauer arrest, but INS-9 overexpression does not enhance dauer arrest in a wild-type or daf-2 mutant background. [Source: WormBase] |
| C06G1.1 | C06G1.1b | C06G1.1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C06G1.4 | C06G1.4.1 | ain-1 | 3 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | ain-1 encodes an unfamiliar protein synergistically required, with LIN-31, for the normal timing of vulval differentiation, independently of LET-60/RAS, and parallel to or downstream of LIN-14/LIN-28/HBL-1. AIN-1 is expressed in cytoplasmic foci (that are probably P bodies) in several tissues, including vulval precursor cells and neurons. AIN-1 coimmunoprecipitates with DCR-1 and ALG-1, also binds ALG-1 in vitro, and does not require DNA or RNA for its binding. in vivo, AIN-1 targets ALG-1 to cytoplasmic foci, in which it colocalizes with DCAP-2. AIN-1 is likely to be a RISC component, since anti-AIN-1 antibodies precipitate 29 different miRNAs, including mir-2, mir-52, mir-58, mir-71, mir-77, and mir-239a. ain-1(ku322) mutants are essentially wild-type, except for sporadically gapped alae and excess seam cell nuclei arising from retarded seam cell fusion. more prominently, ain-1(ku322) suppresses the multivulva phenotype of lin-31(n1053) mutations, while strongly enhancing lin-31(n1053)'s egg-laying defect. the cellular basis of lin-31(n1053).ain-1(ku322) phenotypes is a delay in vulval development in L4 larvae not seen with either mutation alone. ain-1(ku322) has no effect on let-60(n1046) or lin-3(e1275) mutations. ain-1(ku322) suppresses the precocious vulval development of lin-14(RNAi), lin-28 mutants, and hbl-1(RNAi). alg-1 or alg-1 ain-1 mutant alae resemble ain-1 alae, indicating that ALG-1 and AIN-1 act in a common genetic pathway. AIN-1 is homologous to Brugia malayi 14748.m00068, 14052.m00191, and 14963.m01790, and paralogous to C. elegans B0041.2. AIN-1 and its nematode homologs have weak similarity to human TNRC6A (GW182. OMIM:610739) and Drosophila GAWKY. [Source: WormBase] |
| C06G1.4 | C06G1.4.2 | ain-1 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | ain-1 encodes an unfamiliar protein synergistically required, with LIN-31, for the normal timing of vulval differentiation, independently of LET-60/RAS, and parallel to or downstream of LIN-14/LIN-28/HBL-1. AIN-1 is expressed in cytoplasmic foci (that are probably P bodies) in several tissues, including vulval precursor cells and neurons. AIN-1 coimmunoprecipitates with DCR-1 and ALG-1, also binds ALG-1 in vitro, and does not require DNA or RNA for its binding. in vivo, AIN-1 targets ALG-1 to cytoplasmic foci, in which it colocalizes with DCAP-2. AIN-1 is likely to be a RISC component, since anti-AIN-1 antibodies precipitate 29 different miRNAs, including mir-2, mir-52, mir-58, mir-71, mir-77, and mir-239a. ain-1(ku322) mutants are essentially wild-type, except for sporadically gapped alae and excess seam cell nuclei arising from retarded seam cell fusion. more prominently, ain-1(ku322) suppresses the multivulva phenotype of lin-31(n1053) mutations, while strongly enhancing lin-31(n1053)'s egg-laying defect. the cellular basis of lin-31(n1053).ain-1(ku322) phenotypes is a delay in vulval development in L4 larvae not seen with either mutation alone. ain-1(ku322) has no effect on let-60(n1046) or lin-3(e1275) mutations. ain-1(ku322) suppresses the precocious vulval development of lin-14(RNAi), lin-28 mutants, and hbl-1(RNAi). alg-1 or alg-1 ain-1 mutant alae resemble ain-1 alae, indicating that ALG-1 and AIN-1 act in a common genetic pathway. AIN-1 is homologous to Brugia malayi 14748.m00068, 14052.m00191, and 14963.m01790, and paralogous to C. elegans B0041.2. AIN-1 and its nematode homologs have weak similarity to human TNRC6A (GW182. OMIM:610739) and Drosophila GAWKY. [Source: WormBase] |
| C06G1.5 | C06G1.5 | C06G1.5 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C06G1.6 | C06G1.6 | C06G1.6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C07A12.3 | C07A12.3a | nhr-35 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C07A12.7 | C07A12.7a.1 | C07A12.7 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C07A12.7 | C07A12.7a.2 | C07A12.7 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C07A12.7 | C07A12.7b | C07A12.7 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C07A12.7 | C07A12.7c.1 | C07A12.7 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C07A12.7 | C07A12.7c.2 | C07A12.7 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C07A4.2 | C07A4.2 | C07A4.2 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C07B5.4 | C07B5.4a.1 | C07B5.4 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C07B5.4 | C07B5.4a.2 | C07B5.4 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C07B5.4 | C07B5.4b.1 | C07B5.4 | 3 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C07B5.4 | C07B5.4b.2 | C07B5.4 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C07B5.5 | C07B5.5 | nuc-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | The nuc-1 gene encodes a DNase II homolog similar to mammalian and Drosophila DNaseII enzymes and is required for DNA degradation during apoptosis as well as for degradation of dietary DNA during normal feeding. during apoptosis, NUC-1 functions in apoptotic cells at an intermediate stage of DNA degradation, after the killing step, but prior to cell-corpse engulfment. [Source: WormBase] |
| C08A9.10 | C08A9.10 | C08A9.10 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C08A9.9 | C08A9.9.1 | C08A9.9 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C08A9.9 | C08A9.9.2 | C08A9.9 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C09B8.6 | C09B8.6a | hsp-25 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | hsp-25 encodes a member of the small heat shock family of proteins. HSP-25 is expressed throughout development and in vitro, exhibits chaperone activity. HSP-25 localizes to: 1) dense bodies and M lines in body wall muscle, 2) the lining of the pharynx, and 3) to cell-cell junctions in the spermathecal wall. consistent with a role in myofibril organization, HSP-25 binds vinculin and alpha-actinin in vitro. [Source: WormBase] |
| C09B8.6 | C09B8.6b | hsp-25 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | hsp-25 encodes a member of the small heat shock family of proteins. HSP-25 is expressed throughout development and in vitro, exhibits chaperone activity. HSP-25 localizes to: 1) dense bodies and M lines in body wall muscle, 2) the lining of the pharynx, and 3) to cell-cell junctions in the spermathecal wall. consistent with a role in myofibril organization, HSP-25 binds vinculin and alpha-actinin in vitro. [Source: WormBase] |
| C09B8.6 | C09B8.6c.1 | hsp-25 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | hsp-25 encodes a member of the small heat shock family of proteins. HSP-25 is expressed throughout development and in vitro, exhibits chaperone activity. HSP-25 localizes to: 1) dense bodies and M lines in body wall muscle, 2) the lining of the pharynx, and 3) to cell-cell junctions in the spermathecal wall. consistent with a role in myofibril organization, HSP-25 binds vinculin and alpha-actinin in vitro. [Source: WormBase] |
| C09B8.6 | C09B8.6c.2 | hsp-25 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | hsp-25 encodes a member of the small heat shock family of proteins. HSP-25 is expressed throughout development and in vitro, exhibits chaperone activity. HSP-25 localizes to: 1) dense bodies and M lines in body wall muscle, 2) the lining of the pharynx, and 3) to cell-cell junctions in the spermathecal wall. consistent with a role in myofibril organization, HSP-25 binds vinculin and alpha-actinin in vitro. [Source: WormBase] |
| C09B8.6 | C09B8.6c.3 | hsp-25 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | hsp-25 encodes a member of the small heat shock family of proteins. HSP-25 is expressed throughout development and in vitro, exhibits chaperone activity. HSP-25 localizes to: 1) dense bodies and M lines in body wall muscle, 2) the lining of the pharynx, and 3) to cell-cell junctions in the spermathecal wall. consistent with a role in myofibril organization, HSP-25 binds vinculin and alpha-actinin in vitro. [Source: WormBase] |
| C09B8.6 | C09B8.6c.4 | hsp-25 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | hsp-25 encodes a member of the small heat shock family of proteins. HSP-25 is expressed throughout development and in vitro, exhibits chaperone activity. HSP-25 localizes to: 1) dense bodies and M lines in body wall muscle, 2) the lining of the pharynx, and 3) to cell-cell junctions in the spermathecal wall. consistent with a role in myofibril organization, HSP-25 binds vinculin and alpha-actinin in vitro. [Source: WormBase] |
| C09E10.2 | C09E10.2a | dgk-1 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | dgk-1 encodes an ortholog of mammalian diacylglycerol kinase theta (DGKQ). dgk-1 activity functions downstream in a serotonin signaling pathway that regulates locomotion and synaptic transmission. in addition, dgk-1 activity negatively regulates egg laying. dgk-1 genetically interacts with the goa-1 and egl-30 signaling pathways. a GFP::DGK-1 reporter fusion protein is expressed in the excretory canals and in most neurons, including the ventral cord neurons. in neurons, GFP::DGK-1 localizes to axons and cell bodies. when expressed ectopically in HEK293 cells, DGK-1 exhibits DAG kinase activity. [Source: WormBase] |
| C09E10.2 | C09E10.2b | dgk-1 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | dgk-1 encodes an ortholog of mammalian diacylglycerol kinase theta (DGKQ). dgk-1 activity functions downstream in a serotonin signaling pathway that regulates locomotion and synaptic transmission. in addition, dgk-1 activity negatively regulates egg laying. dgk-1 genetically interacts with the goa-1 and egl-30 signaling pathways. a GFP::DGK-1 reporter fusion protein is expressed in the excretory canals and in most neurons, including the ventral cord neurons. in neurons, GFP::DGK-1 localizes to axons and cell bodies. when expressed ectopically in HEK293 cells, DGK-1 exhibits DAG kinase activity. [Source: WormBase] |
| C09E10.2 | C09E10.2c | dgk-1 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | dgk-1 encodes an ortholog of mammalian diacylglycerol kinase theta (DGKQ). dgk-1 activity functions downstream in a serotonin signaling pathway that regulates locomotion and synaptic transmission. in addition, dgk-1 activity negatively regulates egg laying. dgk-1 genetically interacts with the goa-1 and egl-30 signaling pathways. a GFP::DGK-1 reporter fusion protein is expressed in the excretory canals and in most neurons, including the ventral cord neurons. in neurons, GFP::DGK-1 localizes to axons and cell bodies. when expressed ectopically in HEK293 cells, DGK-1 exhibits DAG kinase activity. [Source: WormBase] |
| C09E10.2 | C09E10.2d | dgk-1 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | dgk-1 encodes an ortholog of mammalian diacylglycerol kinase theta (DGKQ). dgk-1 activity functions downstream in a serotonin signaling pathway that regulates locomotion and synaptic transmission. in addition, dgk-1 activity negatively regulates egg laying. dgk-1 genetically interacts with the goa-1 and egl-30 signaling pathways. a GFP::DGK-1 reporter fusion protein is expressed in the excretory canals and in most neurons, including the ventral cord neurons. in neurons, GFP::DGK-1 localizes to axons and cell bodies. when expressed ectopically in HEK293 cells, DGK-1 exhibits DAG kinase activity. [Source: WormBase] |
| C09E10.2 | C09E10.2e | dgk-1 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | dgk-1 encodes an ortholog of mammalian diacylglycerol kinase theta (DGKQ). dgk-1 activity functions downstream in a serotonin signaling pathway that regulates locomotion and synaptic transmission. in addition, dgk-1 activity negatively regulates egg laying. dgk-1 genetically interacts with the goa-1 and egl-30 signaling pathways. a GFP::DGK-1 reporter fusion protein is expressed in the excretory canals and in most neurons, including the ventral cord neurons. in neurons, GFP::DGK-1 localizes to axons and cell bodies. when expressed ectopically in HEK293 cells, DGK-1 exhibits DAG kinase activity. [Source: WormBase] |
| C09F12.1 | C09F12.1.1 | clc-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | clc-1 encodes a claudin homolog, closely similar to CLC-2, that is required for normal cohesion of apical junctions in epithelia. claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water. CLC-1 maintains the impermeability ('barrier function') of epithelia, since clc-1(RNAi) animals have abnormal permeability of the pharynx to dyes. clc-1 is expressed in spermatheca, pharynx, intestine, hypodermis, the excretory-secretory system, and the cell-cell junctions of the vulva. in pharyngeal cells, CLC-1 colocalizes with AJM-1 in long thin lines, parallel to the pharyngeal axis and lining the lumenal surface, that appear to correspond with apical intercellular junctions. [Source: WormBase] |
| C09F12.1 | C09F12.1.2 | clc-1 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | clc-1 encodes a claudin homolog, closely similar to CLC-2, that is required for normal cohesion of apical junctions in epithelia. claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water. CLC-1 maintains the impermeability ('barrier function') of epithelia, since clc-1(RNAi) animals have abnormal permeability of the pharynx to dyes. clc-1 is expressed in spermatheca, pharynx, intestine, hypodermis, the excretory-secretory system, and the cell-cell junctions of the vulva. in pharyngeal cells, CLC-1 colocalizes with AJM-1 in long thin lines, parallel to the pharyngeal axis and lining the lumenal surface, that appear to correspond with apical intercellular junctions. [Source: WormBase] |
| C09F12.3 | C09F12.3 | C09F12.3 | 2 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C09G1.2 | C09G1.2 | C09G1.2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C10A4.1 | C10A4.1 | C10A4.1 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C10A4.3 | C10A4.3 | C10A4.3 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C10A4.5 | C10A4.5 | C10A4.5 | 2 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | |
| C10A4.8 | C10A4.8 | mnm-2 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C10E2.2 | C10E2.2.1 | C10E2.2 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins. [Source: WormBase] |
| C10E2.3 | C10E2.3 | hda-4 | 1 | 23 X | Forward | View as cDNA map | View as Table | Internal | Ensembl | hda-4 encodes a class II histone deacetylase that contains a putative MEF-2 DNA binding domain, a nuclear localization signal domain, and a single catalytic domain and may affect locomotion, body morphology, and growth. interacts with MEF-2 in in vitro assays and is expressed in body-wall muscle, neurons, and hypodermal seam cells [Source: WormBase] |
| C10E2.6 | C10E2.6.1 | C10E2.6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl | |
| C10E2.6 | C10E2.6.2 | C10E2.6 | 1 | 23 X | Reverse | View as cDNA map | View as Table | Internal | Ensembl |