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Genome: Caenorhabditis Elegans | mRNA | miRBase 18 (Nov. 2011), ENSEMBL 65 (Dec. 2011) and RNA22v1.0
Description: List of transcripts that are targeted by all of the below miRNA identifiers simultaneously
miRNA's: cel-miR-5546-5p (MIMAT0022183)
Filtering By: Base pair min value: 12 | Folding energy max value (Kcal/mol): -21 | Min miRNA targets: 1


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Gene IDTranscript IDCommon Gene Name# of miRNA targets
for specified miRNAs
ChromosomeStrand DirectionTranscript Link to view miRNA target predictionsGene LinkDescription
B0310.1B0310.1bB0310.1123 XForwardView as cDNA map |
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Ensembl
B0310.1 encodes a nematode-specific transmembrane protein. loss of B0310.1 activity via RNAi results in reduced fat content in wild-type and tub-1 mutant animals, suggesting that B0301.1 plays a role in lipid metabolism. [Source: WormBase]
B0310.3B0310.3B0310.3123 XReverseView as cDNA map |
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Ensembl
B0395.3B0395.3.1B0395.3123 XReverseView as cDNA map |
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Ensembl
B0395.3 is orthologous to the human gene CHOLINE ACETYLTRANSFERASE ISOFORM R (CHAT. OMIM:118490), which when mutated leads to disease. [Source: WormBase]
B0395.3B0395.3.2B0395.3123 XReverseView as cDNA map |
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Ensembl
B0395.3 is orthologous to the human gene CHOLINE ACETYLTRANSFERASE ISOFORM R (CHAT. OMIM:118490), which when mutated leads to disease. [Source: WormBase]
B0416.4B0416.4B0416.4123 XForwardView as cDNA map |
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Ensembl
B0563.4B0563.4.1tmbi-4123 XForwardView as cDNA map |
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Ensembl
B0563.4B0563.4.2tmbi-4123 XForwardView as cDNA map |
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Ensembl
C02B4.1C02B4.1adt-1323 XForwardView as cDNA map |
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Ensembl
The adt-1 gene encodes a metalloproteinase with disintegrin-like and metalloproteinase with thrombospondin type I motifs (ADAMTS) that is required for male tail morphogenesis. [Source: WormBase]
C02C6.1C02C6.1adyn-1123 XForwardView as cDNA map |
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Ensembl
dyn-1 encodes the C. elegans ortholog of the dynamin GTPase. dyn-1 activity is required for endocytosis, synaptic vesicle recycling, cytokinesis, and the CED-1 pathway that regulates engulfment and degradation of apoptotic cells. mutations in dyn-1 affect locomotion, egg-laying, defecation, and embryonic development, indicating that dyn-1's endocytic function is required for a number of diverse processes. dyn-1 reporter fusion constructs are expressed in motor neurons, intestinal cells, and pharyngeal muscle. [Source: WormBase]
C02C6.1C02C6.1bdyn-1123 XForwardView as cDNA map |
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Ensembl
dyn-1 encodes the C. elegans ortholog of the dynamin GTPase. dyn-1 activity is required for endocytosis, synaptic vesicle recycling, cytokinesis, and the CED-1 pathway that regulates engulfment and degradation of apoptotic cells. mutations in dyn-1 affect locomotion, egg-laying, defecation, and embryonic development, indicating that dyn-1's endocytic function is required for a number of diverse processes. dyn-1 reporter fusion constructs are expressed in motor neurons, intestinal cells, and pharyngeal muscle. [Source: WormBase]
C02F12.7C02F12.7tag-278323 XReverseView as cDNA map |
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Ensembl
C02H7.1C02H7.1dyf-11323 XForwardView as cDNA map |
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Ensembl
dyf-11 encodes a conserved protein orthologous to the human microtubule-binding protein MIP-T3 and that contains a lysine-rich region and a C-terminal coiled-coil domain present in a number of intraflagellar transport (IFT) complex B proteins. DYF-11 activity is required continuously in sensory neurons for formation of medial and distal ciliary segments and thus, for normal sensory cilium morphology and function and chemotaxis. a dyf-11::gfp promoter fusion is expressed in all ciliated sensory neurons as well as in the AQR, PQR, ADE, and PDR neurons. a DYF-11::GFP protein fusion is detected throughout the cilium and appears to localize to IFT-B particles in a manner consistent with an early role in IFT-B particle assembly. dyf-11 expression in ciliated neurons is dependent upon the presence of the DAF-19 RFX transcription factor. [Source: WormBase]
C03B1.7C03B1.7C03B1.7123 XForwardView as cDNA map |
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C03F11.2C03F11.2C03F11.2123 XReverseView as cDNA map |
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C04A11.4C04A11.4adm-2123 XForwardView as cDNA map |
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Ensembl
adm-2 encodes a protein containing a snake venom disintegrin-domain and a metalloprotease-like domain (i.e., a protein of the ADAM family). like ADM-1, ADM-2 is homologous to a mammalian sperm glycoprotein (PH-30/fertilin) implicated in sperm-egg fusion, and ADM-2 might thus be a fusogenic protein mediating the merging of plasma membranes during development. [Source: WormBase]
C04B4.3C04B4.3lips-2123 XForwardView as cDNA map |
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Ensembl
C04E7.3C04E7.3C04E7.3123 XReverseView as cDNA map |
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C04F6.1C04F6.1vit-5123 XForwardView as cDNA map |
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Ensembl
vit-5 encodes a vitellogenin, a lipid-binding protein precursor related to vertebrate vitellogenins and mammalian ApoB-100, a core LDL particle constituent. by homology, VIT-5 is predicted to function as a lipid transport protein. loss of vit-5 activity via large-scale RNA-mediated interference (RNAi) screens indicates that VIT-5 is required for embryogenesis and normal rates of postembryonic growth. VIT-5 is a major yolk component and is expressed exclusively in the adult hermaphrodite intestine from which it is secreted into the pseudocoelomic space and taken up by oocytes. [Source: WormBase]
C05D9.1C05D9.1.1snx-1123 XForwardView as cDNA map |
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C05D9.1C05D9.1.2snx-1123 XForwardView as cDNA map |
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C05D9.1C05D9.1.3snx-1123 XForwardView as cDNA map |
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C05D9.9C05D9.9aC05D9.9123 XReverseView as cDNA map |
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C05D9.9C05D9.9bC05D9.9123 XReverseView as cDNA map |
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C05E11.4C05E11.4amt-1123 XForwardView as cDNA map |
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amt-1 encodes a transmembrane transporter that by homology, is predicted to transport ammonium ions across the plasma membrane. as loss of amt-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of AMT-1 in C. elegans development and/or behavior is not yet known. [Source: WormBase]
C05E7.3C05E7.3C05E7.3123 XReverseView as cDNA map |
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C05G5.5C05G5.5C05G5.5123 XReverseView as cDNA map |
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C06E2.3C06E2.3ubc-21123 XForwardView as cDNA map |
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C06G1.5C06G1.5C06G1.5123 XReverseView as cDNA map |
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C07A12.3C07A12.3anhr-35123 XForwardView as cDNA map |
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C07A12.5C07A12.5aspr-3223 XForwardView as cDNA map |
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C09G1.2C09G1.2C09G1.2123 XReverseView as cDNA map |
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C09G1.4C09G1.4C09G1.4123 XReverseView as cDNA map |
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C10A4.8C10A4.8mnm-2123 XReverseView as cDNA map |
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C10E2.2C10E2.2.1C10E2.2123 XForwardView as cDNA map |
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This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins. [Source: WormBase]
C11G10.2C11G10.2C11G10.2123 XReverseView as cDNA map |
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C11G6.3C11G6.3C11G6.3223 XForwardView as cDNA map |
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Ensembl
C11G6.3 encodes a plant homeodomain-containing protein that is related to the ING (Inhibitor of Growth) family of proteins that function in regulation of gene expression and are candidate tumor suppressors. [Source: WormBase]
C11H1.2C11H1.2C11H1.2123 XReverseView as cDNA map |
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C14A11.3C14A11.3bcgef-1123 XForwardView as cDNA map |
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C14A11.5C14A11.5C14A11.5123 XReverseView as cDNA map |
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C14A11.7C14A11.7ssr-2123 XReverseView as cDNA map |
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C14F11.4C14F11.4aC14F11.4123 XReverseView as cDNA map |
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C14F11.4C14F11.4bC14F11.4123 XReverseView as cDNA map |
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C14H10.3C14H10.3aC14H10.3223 XReverseView as cDNA map |
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C14H10.3C14H10.3b.1C14H10.3223 XReverseView as cDNA map |
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C14H10.3C14H10.3b.2C14H10.3223 XReverseView as cDNA map |
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C14H10.4C14H10.4str-74123 XReverseView as cDNA map |
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C15B12.6C15B12.6C15B12.6223 XReverseView as cDNA map |
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Ensembl
C15C7.2C15C7.2.1klp-8123 XForwardView as cDNA map |
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Ensembl
klp-8 encodes an atypical kinesin-like motor protein with the motor domain in the N-terminus. the motor domain of KLP-8 exhibits poor homology to the globular motor domain of the kinesin heavy chain. [Source: WormBase]
C15C7.2C15C7.2.2klp-8123 XForwardView as cDNA map |
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Ensembl
klp-8 encodes an atypical kinesin-like motor protein with the motor domain in the N-terminus. the motor domain of KLP-8 exhibits poor homology to the globular motor domain of the kinesin heavy chain. [Source: WormBase]
C16B8.1C16B8.1.1lin-18123 XForwardView as cDNA map |
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Ensembl
lin-18 encodes a predicted receptor tyrosine kinase that is a member of the Ryk/Derailed family of tyrosine kinase-related receptors (OMIM:600524, mutations in humans are associated with cleft palate). in C. elegans, LIN-18 is required for establishing the polarity of the secondary vulval cell lineage produced by the P7.p vulval precursor cell. LIN-18 may be a receptor for Wnt-like signaling molecules, and in vulval development appears to function independently of, but in parallel with, LIN-17, a Frizzled-like Wnt receptor, also required for proper orientation of the P7.p lineage. a lin-18 reporter gene is expressed in body wall muscle, neurons, and the developing vulva. in the vulva, expression is detected in P5.p, P6.p, and P7.p and all of their descendants during the L3 and L4 larval stages. [Source: WormBase]
C16B8.1C16B8.1.2lin-18123 XForwardView as cDNA map |
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Ensembl
lin-18 encodes a predicted receptor tyrosine kinase that is a member of the Ryk/Derailed family of tyrosine kinase-related receptors (OMIM:600524, mutations in humans are associated with cleft palate). in C. elegans, LIN-18 is required for establishing the polarity of the secondary vulval cell lineage produced by the P7.p vulval precursor cell. LIN-18 may be a receptor for Wnt-like signaling molecules, and in vulval development appears to function independently of, but in parallel with, LIN-17, a Frizzled-like Wnt receptor, also required for proper orientation of the P7.p lineage. a lin-18 reporter gene is expressed in body wall muscle, neurons, and the developing vulva. in the vulva, expression is detected in P5.p, P6.p, and P7.p and all of their descendants during the L3 and L4 larval stages. [Source: WormBase]
C16E9.1C16E9.1C16E9.1123 XForwardView as cDNA map |
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C16H3.3C16H3.3aC16H3.3123 XReverseView as cDNA map |
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C16H3.3C16H3.3bC16H3.3123 XReverseView as cDNA map |
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C17G1.2C17G1.2C17G1.2123 XForwardView as cDNA map |
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C17G1.3C17G1.3augt-23123 XReverseView as cDNA map |
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C17G1.3C17G1.3b.1ugt-23123 XReverseView as cDNA map |
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C17G1.3C17G1.3b.2ugt-23123 XReverseView as cDNA map |
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C17G1.7C17G1.7.1C17G1.7123 XReverseView as cDNA map |
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C18B12.3C18B12.3dsc-1123 XReverseView as cDNA map |
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C18B12.6C18B12.6C18B12.6123 XReverseView as cDNA map |
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C23F12.1C23F12.1afln-2123 XForwardView as cDNA map |
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C23F12.1C23F12.1bfln-2123 XForwardView as cDNA map |
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C23H4.1C23H4.1.1cab-1123 XReverseView as cDNA map |
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Novel protein which has a C-terminal motif weakly homologous to mouse NPDC-1 and is involved in synaptic regulation. it is expressed in various neurons including ventral cord and tail ganglion neurons. it physically interacts with AEX-3, which is a guanine nucleotide exchange factor for the Rab3 GTPase. [Source: WormBase]
C23H4.1C23H4.1.2cab-1123 XReverseView as cDNA map |
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Ensembl
Novel protein which has a C-terminal motif weakly homologous to mouse NPDC-1 and is involved in synaptic regulation. it is expressed in various neurons including ventral cord and tail ganglion neurons. it physically interacts with AEX-3, which is a guanine nucleotide exchange factor for the Rab3 GTPase. [Source: WormBase]
C23H4.1C23H4.1.3cab-1123 XReverseView as cDNA map |
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Ensembl
Novel protein which has a C-terminal motif weakly homologous to mouse NPDC-1 and is involved in synaptic regulation. it is expressed in various neurons including ventral cord and tail ganglion neurons. it physically interacts with AEX-3, which is a guanine nucleotide exchange factor for the Rab3 GTPase. [Source: WormBase]
C23H4.1C23H4.1.4cab-1123 XReverseView as cDNA map |
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Ensembl
Novel protein which has a C-terminal motif weakly homologous to mouse NPDC-1 and is involved in synaptic regulation. it is expressed in various neurons including ventral cord and tail ganglion neurons. it physically interacts with AEX-3, which is a guanine nucleotide exchange factor for the Rab3 GTPase. [Source: WormBase]
C23H4.1C23H4.1.5cab-1123 XReverseView as cDNA map |
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Ensembl
Novel protein which has a C-terminal motif weakly homologous to mouse NPDC-1 and is involved in synaptic regulation. it is expressed in various neurons including ventral cord and tail ganglion neurons. it physically interacts with AEX-3, which is a guanine nucleotide exchange factor for the Rab3 GTPase. [Source: WormBase]
C23H4.7C23H4.7C23H4.7123 XForwardView as cDNA map |
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Ensembl
C23H4.8C23H4.8C23H4.8223 XForwardView as cDNA map |
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C24A8.4C24A8.4cst-2223 XReverseView as cDNA map |
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Ensembl
C25F6.2C25F6.2b.1dlg-1123 XForwardView as cDNA map |
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dlg-1 encodes a MAGUK protein, orthologous to Drosophila disks large, that is physically located to adherens junctions in all epithelia and that is genetically required for organization of the embryonic gut epithelium into an coherent tube. [Source: WormBase]
C25G6.3C25G6.3C25G6.3123 XReverseView as cDNA map |
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C26B9.6C26B9.6C26B9.6123 XReverseView as cDNA map |
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C26G2.1C26G2.1syg-2223 XForwardView as cDNA map |
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syg-2 encodes a transmembrane protein that is a member of the immunoglobulin superfamily of proteins. during larval development, SYG-2 activity is required in vulval epithelial cells for proper synaptic specificity of the HSNL neuron. in regulating synapse formation, SYG-2 acts as a guidepost protein for the SYG-1 receptor that interacts with SYG-2 and acts within HSNL to regulate synaptic specificity. a SYG-2::GFP fusion protein is expressed in the primary vulval cell lineages beginning at the L3 larval stage, with expression increasing during the L4 stage and finally disappearing by adulthood. in embryos, SYG-2::GFP expression is detected in some head neurons and body wall muscles, the latter of which also express the reporter during the L1 and L2 larval stages. [Source: WormBase]
C29F7.5C29F7.5fkh-4123 XReverseView as cDNA map |
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fkh-4 encodes a member of the forkhead domain transcription factor family. [Source: WormBase]
C30F2.2C30F2.2C30F2.2123 XReverseView as cDNA map |
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C30G4.7C30G4.7C30G4.7123 XReverseView as cDNA map |
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C31E10.5C31E10.5C31E10.5123 XReverseView as cDNA map |
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C31E10.8C31E10.8tbc-19123 XReverseView as cDNA map |
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C31H2.2C31H2.2dpy-8123 XReverseView as cDNA map |
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dpy-8 encodes a collagen with a nematode-specific N-terminal domain that is required for normal body morphology and (perhaps) for a normal embryonic cell division rate. dpy-8 interacts genetically with emb-5 and glp-1. [Source: WormBase]
C31H2.4C31H2.4C31H2.4123 XReverseView as cDNA map |
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C31H2.4 encodes a possible 4-hydroxyphenylpyruvate dioxygenase, orthologous to human HPDL/GLOXD1, and paralogous to HPD-1 and human HPD (OMIM:609695, mutated in tyrosinemia type III). C31H2.4 has no obvious function in mass RNAi experiments. [Source: WormBase]
C33D12.3C33D12.3twk-26123 XReverseView as cDNA map |
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C33D3.4C33D3.4C33D3.4123 XForwardView as cDNA map |
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C33E10.5C33E10.5C33E10.5223 XForwardView as cDNA map |
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C33E10.8C33E10.8C33E10.8123 XReverseView as cDNA map |
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This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins. [Source: WormBase]
C33G3.1C33G3.1b.1dyc-1123 XForwardView as cDNA map |
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dyc-1 encodes a homolog of murine CAPON, a protein associated with neuronal nitric oxide synthase that regulates its interactions with PSD95. DYC-1 is expressed in muscle, and is required for a dystrophin-related function in muscle. [Source: WormBase]
C33G3.1C33G3.1b.2dyc-1123 XForwardView as cDNA map |
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dyc-1 encodes a homolog of murine CAPON, a protein associated with neuronal nitric oxide synthase that regulates its interactions with PSD95. DYC-1 is expressed in muscle, and is required for a dystrophin-related function in muscle. [Source: WormBase]
C34E11.3C34E11.3atag-241223 XForwardView as cDNA map |
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C34E11.3C34E11.3btag-241223 XForwardView as cDNA map |
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C34E11.3C34E11.3ctag-241223 XForwardView as cDNA map |
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C34E11.3C34E11.3dtag-241223 XForwardView as cDNA map |
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C34F6.10C34F6.10C34F6.10123 XReverseView as cDNA map |
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C34F6.1C34F6.1C34F6.1123 XReverseView as cDNA map |
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C34F6.2C34F6.2col-178123 XForwardView as cDNA map |
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C34F6.3C34F6.3col-179123 XForwardView as cDNA map |
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C34F6.8C34F6.8.1idh-2123 XForwardView as cDNA map |
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C34F6.8C34F6.8.2idh-2123 XForwardView as cDNA map |
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C34F6.8C34F6.8.3idh-2123 XForwardView as cDNA map |
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C35B8.3C35B8.3bC35B8.3123 XForwardView as cDNA map |
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We gratefully acknowledge support of this work by the William M. Keck Foundation