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Genome: Mus Musculus | mRNA | miRBase 18 (Nov. 2011), ENSEMBL 65 (Dec. 2011) and RNA22v2.0
Description: List of transcripts that are targeted by all of the below miRNA identifiers simultaneously
miRNA's: mmu-miR-669a-3p (MIMAT0017243)
Filtering By: Base pair min value: 12 | Folding energy max value (Kcal/mol): -12 | Min miRNA targets: 1 | Max p-value: .1


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Gene IDTranscript IDCommon Gene Name# of miRNA targets
for specified miRNAs
ChromosomeStrand DirectionTranscript Link to view miRNA target predictionsGene LinkDescription
ENSMUSG00000000817ENSMUST00000000834Fasl11ReverseView as cDNA map |
View as Table
Internal |
Ensembl
Fas ligand (TNF superfamily, member 6) [Source:MGI Symbol;Acc:MGI:99255]
ENSMUSG00000002459ENSMUST00000002533Rgs2041ReverseView as cDNA map |
View as Table
Internal |
Ensembl
regulator of G-protein signaling 20 [Source:MGI Symbol;Acc:MGI:1929866]
ENSMUSG00000002459ENSMUST00000118000Rgs2041ReverseView as cDNA map |
View as Table
Internal |
Ensembl
regulator of G-protein signaling 20 [Source:MGI Symbol;Acc:MGI:1929866]
ENSMUSG00000003721ENSMUST00000003818Insig211ReverseView as cDNA map |
View as Table
Internal |
Ensembl
insulin induced gene 2 [Source:MGI Symbol;Acc:MGI:1920249]
ENSMUSG00000003721ENSMUST00000071064Insig211ReverseView as cDNA map |
View as Table
Internal |
Ensembl
insulin induced gene 2 [Source:MGI Symbol;Acc:MGI:1920249]
ENSMUSG00000003721ENSMUST00000159085Insig211ReverseView as cDNA map |
View as Table
Internal |
Ensembl
insulin induced gene 2 [Source:MGI Symbol;Acc:MGI:1920249]
ENSMUSG00000003721ENSMUST00000160968Insig211ReverseView as cDNA map |
View as Table
Internal |
Ensembl
insulin induced gene 2 [Source:MGI Symbol;Acc:MGI:1920249]
ENSMUSG00000004872ENSMUST00000004994Pax311ReverseView as cDNA map |
View as Table
Internal |
Ensembl
paired box gene 3 [Source:MGI Symbol;Acc:MGI:97487]
ENSMUSG00000004872ENSMUST00000087086Pax311ReverseView as cDNA map |
View as Table
Internal |
Ensembl
paired box gene 3 [Source:MGI Symbol;Acc:MGI:97487]
ENSMUSG00000005338ENSMUST00000111220Cadm351ReverseView as cDNA map |
View as Table
Internal |
Ensembl
cell adhesion molecule 3 [Source:MGI Symbol;Acc:MGI:2137858]
ENSMUSG00000006301ENSMUST00000016309Tmbim111ReverseView as cDNA map |
View as Table
Internal |
Ensembl
transmembrane BAX inhibitor motif containing 1 [Source:MGI Symbol;Acc:MGI:1916910]
ENSMUSG00000006301ENSMUST00000113796Tmbim111ReverseView as cDNA map |
View as Table
Internal |
Ensembl
transmembrane BAX inhibitor motif containing 1 [Source:MGI Symbol;Acc:MGI:1916910]
ENSMUSG00000006403ENSMUST00000006570Adamts431ForwardView as cDNA map |
View as Table
Internal |
Ensembl
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 [Source:MGI Symbol;Acc:MGI:1339949]
ENSMUSG00000006403ENSMUST00000111314Adamts431ForwardView as cDNA map |
View as Table
Internal |
Ensembl
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 [Source:MGI Symbol;Acc:MGI:1339949]
ENSMUSG00000006403ENSMUST00000111315Adamts431ForwardView as cDNA map |
View as Table
Internal |
Ensembl
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 [Source:MGI Symbol;Acc:MGI:1339949]
ENSMUSG00000006411ENSMUST00000006578Pvrl441ForwardView as cDNA map |
View as Table
Internal |
Ensembl
poliovirus receptor-related 4 [Source:MGI Symbol;Acc:MGI:1918990]
ENSMUSG00000006411ENSMUST00000111286Pvrl441ForwardView as cDNA map |
View as Table
Internal |
Ensembl
poliovirus receptor-related 4 [Source:MGI Symbol;Acc:MGI:1918990]
ENSMUSG00000009418ENSMUST00000040599Nav111ReverseView as cDNA map |
View as Table
Internal |
Ensembl
neuron navigator 1 [Source:MGI Symbol;Acc:MGI:2183683]
ENSMUSG00000009907ENSMUST00000094646Vps4b11ReverseView as cDNA map |
View as Table
Internal |
Ensembl
vacuolar protein sorting 4b (yeast) [Source:MGI Symbol;Acc:MGI:1100499]
ENSMUSG00000018196ENSMUST00000145571Glrx211ForwardView as cDNA map |
View as Table
Internal |
Ensembl
glutaredoxin 2 (thioltransferase) [Source:MGI Symbol;Acc:MGI:1916617]
ENSMUSG00000025920ENSMUST00000054668Stau211ReverseView as cDNA map |
View as Table
Internal |
Ensembl
staufen (RNA binding protein) homolog 2 (Drosophila) [Source:MGI Symbol;Acc:MGI:1352508]
ENSMUSG00000025920ENSMUST00000162751Stau211ReverseView as cDNA map |
View as Table
Internal |
Ensembl
staufen (RNA binding protein) homolog 2 (Drosophila) [Source:MGI Symbol;Acc:MGI:1352508]
ENSMUSG00000025927ENSMUST00000027059Tcfap2b21ForwardView as cDNA map |
View as Table
Internal |
Ensembl
transcription factor AP-2 beta [Source:MGI Symbol;Acc:MGI:104672]
ENSMUSG00000025932ENSMUST00000027066Eya121ReverseView as cDNA map |
View as Table
Internal |
Ensembl
eyes absent 1 homolog (Drosophila) [Source:MGI Symbol;Acc:MGI:109344]
ENSMUSG00000025932ENSMUST00000080664Eya121ReverseView as cDNA map |
View as Table
Internal |
Ensembl
eyes absent 1 homolog (Drosophila) [Source:MGI Symbol;Acc:MGI:109344]
ENSMUSG00000025932ENSMUST00000168081Eya121ReverseView as cDNA map |
View as Table
Internal |
Ensembl
eyes absent 1 homolog (Drosophila) [Source:MGI Symbol;Acc:MGI:109344]
ENSMUSG00000025940ENSMUST00000065373Tmem7011ForwardView as cDNA map |
View as Table
Internal |
Ensembl
transmembrane protein 70 [Source:MGI Symbol;Acc:MGI:1915068]
ENSMUSG00000025969ENSMUST00000027112Nrp211ForwardView as cDNA map |
View as Table
Internal |
Ensembl
neuropilin 2 [Source:MGI Symbol;Acc:MGI:1100492]
ENSMUSG00000025969ENSMUST00000063594Nrp251ForwardView as cDNA map |
View as Table
Internal |
Ensembl
neuropilin 2 [Source:MGI Symbol;Acc:MGI:1100492]
ENSMUSG00000025969ENSMUST00000075144Nrp251ForwardView as cDNA map |
View as Table
Internal |
Ensembl
neuropilin 2 [Source:MGI Symbol;Acc:MGI:1100492]
ENSMUSG00000025969ENSMUST00000102822Nrp251ForwardView as cDNA map |
View as Table
Internal |
Ensembl
neuropilin 2 [Source:MGI Symbol;Acc:MGI:1100492]
ENSMUSG00000025969ENSMUST00000114155Nrp211ForwardView as cDNA map |
View as Table
Internal |
Ensembl
neuropilin 2 [Source:MGI Symbol;Acc:MGI:1100492]
ENSMUSG00000025969ENSMUST00000114157Nrp251ForwardView as cDNA map |
View as Table
Internal |
Ensembl
neuropilin 2 [Source:MGI Symbol;Acc:MGI:1100492]
ENSMUSG00000025986ENSMUST00000027131Slc39a1011ReverseView as cDNA map |
View as Table
Internal |
Ensembl
solute carrier family 39 (zinc transporter), member 10 [Source:MGI Symbol;Acc:MGI:1914515]
ENSMUSG00000025997ENSMUST00000027146Ikzf221ReverseView as cDNA map |
View as Table
Internal |
Ensembl
IKAROS family zinc finger 2 [Source:MGI Symbol;Acc:MGI:1342541]
ENSMUSG00000026000ENSMUST00000027149Lancl111ReverseView as cDNA map |
View as Table
Internal |
Ensembl
LanC (bacterial lantibiotic synthetase component C)-like 1 [Source:MGI Symbol;Acc:MGI:1336997]
ENSMUSG00000026000ENSMUST00000113979Lancl111ReverseView as cDNA map |
View as Table
Internal |
Ensembl
LanC (bacterial lantibiotic synthetase component C)-like 1 [Source:MGI Symbol;Acc:MGI:1336997]
ENSMUSG00000026029ENSMUST00000027189Casp811ForwardView as cDNA map |
View as Table
Internal |
Ensembl
caspase 8 [Source:MGI Symbol;Acc:MGI:1261423]
ENSMUSG00000026029ENSMUST00000165549Casp811ForwardView as cDNA map |
View as Table
Internal |
Ensembl
caspase 8 [Source:MGI Symbol;Acc:MGI:1261423]
ENSMUSG00000026070ENSMUST00000097771Il18r111ForwardView as cDNA map |
View as Table
Internal |
Ensembl
interleukin 18 receptor 1 [Source:MGI Symbol;Acc:MGI:105383]
ENSMUSG00000026070ENSMUST00000108044Il18r131ForwardView as cDNA map |
View as Table
Internal |
Ensembl
interleukin 18 receptor 1 [Source:MGI Symbol;Acc:MGI:105383]
ENSMUSG00000026094ENSMUST00000027263Stk17b21ReverseView as cDNA map |
View as Table
Internal |
Ensembl
serine/threonine kinase 17b (apoptosis-inducing) [Source:MGI Symbol;Acc:MGI:2138162]
ENSMUSG00000026103ENSMUST00000114510Gls11ReverseView as cDNA map |
View as Table
Internal |
Ensembl
glutaminase [Source:MGI Symbol;Acc:MGI:95752]
ENSMUSG00000026112ENSMUST000000272866330578E17Rik31ReverseView as cDNA map |
View as Table
Internal |
Ensembl
RIKEN cDNA 6330578E17 gene [Source:MGI Symbol;Acc:MGI:1923428]
ENSMUSG00000026121ENSMUST00000027295Sema4c11ReverseView as cDNA map |
View as Table
Internal |
Ensembl
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C [Source:MGI Symbol;Acc:MGI:109252]
ENSMUSG00000026121ENSMUST00000114990Sema4c11ReverseView as cDNA map |
View as Table
Internal |
Ensembl
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C [Source:MGI Symbol;Acc:MGI:109252]
ENSMUSG00000026121ENSMUST00000114991Sema4c11ReverseView as cDNA map |
View as Table
Internal |
Ensembl
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C [Source:MGI Symbol;Acc:MGI:109252]
ENSMUSG00000026121ENSMUST00000114992Sema4c11ReverseView as cDNA map |
View as Table
Internal |
Ensembl
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C [Source:MGI Symbol;Acc:MGI:109252]
ENSMUSG00000026127ENSMUST00000027303Imp411ForwardView as cDNA map |
View as Table
Internal |
Ensembl
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) [Source:MGI Symbol;Acc:MGI:106572]
ENSMUSG00000026209ENSMUST00000066668Dnpep11ReverseView as cDNA map |
View as Table
Internal |
Ensembl
aspartyl aminopeptidase [Source:MGI Symbol;Acc:MGI:1278328]
ENSMUSG00000026209ENSMUST00000171858Dnpep11ReverseView as cDNA map |
View as Table
Internal |
Ensembl
aspartyl aminopeptidase [Source:MGI Symbol;Acc:MGI:1278328]
ENSMUSG00000026235ENSMUST00000027451Epha441ReverseView as cDNA map |
View as Table
Internal |
Ensembl
Eph receptor A4 [Source:MGI Symbol;Acc:MGI:98277]
ENSMUSG00000026235ENSMUST00000113540Epha441ReverseView as cDNA map |
View as Table
Internal |
Ensembl
Eph receptor A4 [Source:MGI Symbol;Acc:MGI:98277]
ENSMUSG00000026240ENSMUST00000027446Cops7b11ForwardView as cDNA map |
View as Table
Internal |
Ensembl
COP9 (constitutive photomorphogenic) homolog, subunit 7b (Arabidopsis thaliana) [Source:MGI Symbol;Acc:MGI:1349388]
ENSMUSG00000026240ENSMUST00000121534Cops7b11ForwardView as cDNA map |
View as Table
Internal |
Ensembl
COP9 (constitutive photomorphogenic) homolog, subunit 7b (Arabidopsis thaliana) [Source:MGI Symbol;Acc:MGI:1349388]
ENSMUSG00000026275ENSMUST00000027494Ppp1r711ForwardView as cDNA map |
View as Table
Internal |
Ensembl
protein phosphatase 1, regulatory (inhibitor) subunit 7 [Source:MGI Symbol;Acc:MGI:1913635]
ENSMUSG00000026289ENSMUST00000027512Atg16l111ForwardView as cDNA map |
View as Table
Internal |
Ensembl
autophagy-related 16-like 1 (yeast) [Source:MGI Symbol;Acc:MGI:1924290]
ENSMUSG00000026289ENSMUST00000113186Atg16l111ForwardView as cDNA map |
View as Table
Internal |
Ensembl
autophagy-related 16-like 1 (yeast) [Source:MGI Symbol;Acc:MGI:1924290]
ENSMUSG00000026312ENSMUST00000086681Cdh751ForwardView as cDNA map |
View as Table
Internal |
Ensembl
cadherin 7, type 2 [Source:MGI Symbol;Acc:MGI:2442792]
ENSMUSG00000026315ENSMUST00000000514Serpinb831ForwardView as cDNA map |
View as Table
Internal |
Ensembl
serine (or cysteine) peptidase inhibitor, clade B, member 8 [Source:MGI Symbol;Acc:MGI:894657]
ENSMUSG00000026315ENSMUST00000112706Serpinb831ForwardView as cDNA map |
View as Table
Internal |
Ensembl
serine (or cysteine) peptidase inhibitor, clade B, member 8 [Source:MGI Symbol;Acc:MGI:894657]
ENSMUSG00000026321ENSMUST00000027559Tnfrsf11a111ForwardView as cDNA map |
View as Table
Internal |
Ensembl
tumor necrosis factor receptor superfamily, member 11a [Source:MGI Symbol;Acc:MGI:1314891]
ENSMUSG00000026339ENSMUST00000036025Ccdc9311ForwardView as cDNA map |
View as Table
Internal |
Ensembl
coiled-coil domain containing 93 [Source:MGI Symbol;Acc:MGI:1918079]
ENSMUSG00000026344ENSMUST00000159417Lypd131ReverseView as cDNA map |
View as Table
Internal |
Ensembl
Ly6/Plaur domain containing 1 [Source:MGI Symbol;Acc:MGI:1919835]
ENSMUSG00000026361ENSMUST00000018337Cdc7311ReverseView as cDNA map |
View as Table
Internal |
Ensembl
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:2384876]
ENSMUSG00000026383ENSMUST00000052404Epb4.1l531ReverseView as cDNA map |
View as Table
Internal |
Ensembl
erythrocyte protein band 4.1-like 5 [Source:MGI Symbol;Acc:MGI:103006]
ENSMUSG00000026383ENSMUST00000163147Epb4.1l531ReverseView as cDNA map |
View as Table
Internal |
Ensembl
erythrocyte protein band 4.1-like 5 [Source:MGI Symbol;Acc:MGI:103006]
ENSMUSG00000026395ENSMUST00000027645Ptprc31ReverseView as cDNA map |
View as Table
Internal |
Ensembl
protein tyrosine phosphatase, receptor type, C [Source:MGI Symbol;Acc:MGI:97810]
ENSMUSG00000026395ENSMUST00000081416Ptprc31ReverseView as cDNA map |
View as Table
Internal |
Ensembl
protein tyrosine phosphatase, receptor type, C [Source:MGI Symbol;Acc:MGI:97810]
ENSMUSG00000026395ENSMUST00000112036Ptprc31ReverseView as cDNA map |
View as Table
Internal |
Ensembl
protein tyrosine phosphatase, receptor type, C [Source:MGI Symbol;Acc:MGI:97810]
ENSMUSG00000026395ENSMUST00000112038Ptprc31ReverseView as cDNA map |
View as Table
Internal |
Ensembl
protein tyrosine phosphatase, receptor type, C [Source:MGI Symbol;Acc:MGI:97810]
ENSMUSG00000026409ENSMUST00000050406Pfkfb2181ReverseView as cDNA map |
View as Table
Internal |
Ensembl
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 [Source:MGI Symbol;Acc:MGI:107815]
ENSMUSG00000026409ENSMUST00000066863Pfkfb2151ReverseView as cDNA map |
View as Table
Internal |
Ensembl
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 [Source:MGI Symbol;Acc:MGI:107815]
ENSMUSG00000026409ENSMUST00000169659Pfkfb2151ReverseView as cDNA map |
View as Table
Internal |
Ensembl
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 [Source:MGI Symbol;Acc:MGI:107815]
ENSMUSG00000026413ENSMUST00000027667Pkp111ReverseView as cDNA map |
View as Table
Internal |
Ensembl
plakophilin 1 [Source:MGI Symbol;Acc:MGI:1328359]
ENSMUSG00000026413ENSMUST00000163260Pkp111ReverseView as cDNA map |
View as Table
Internal |
Ensembl
plakophilin 1 [Source:MGI Symbol;Acc:MGI:1328359]
ENSMUSG00000026434ENSMUST00000062264Nucks121ForwardView as cDNA map |
View as Table
Internal |
Ensembl
nuclear casein kinase and cyclin-dependent kinase substrate 1 [Source:MGI Symbol;Acc:MGI:1934811]
ENSMUSG00000026452ENSMUST00000121990Syt231ForwardView as cDNA map |
View as Table
Internal |
Ensembl
synaptotagmin II [Source:MGI Symbol;Acc:MGI:99666]
ENSMUSG00000026456ENSMUST00000027726Cyb5r131ForwardView as cDNA map |
View as Table
Internal |
Ensembl
cytochrome b5 reductase 1 [Source:MGI Symbol;Acc:MGI:1919267]
ENSMUSG00000026458ENSMUST00000168515Ppfia411ReverseView as cDNA map |
View as Table
Internal |
Ensembl
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 [Source:MGI Symbol;Acc:MGI:1915757]
ENSMUSG00000026473ENSMUST00000086199Glul11ForwardView as cDNA map |
View as Table
Internal |
Ensembl
glutamate-ammonia ligase (glutamine synthetase) [Source:MGI Symbol;Acc:MGI:95739]
ENSMUSG00000026482ENSMUST00000027760Rgl131ReverseView as cDNA map |
View as Table
Internal |
Ensembl
ral guanine nucleotide dissociation stimulator,-like 1 [Source:MGI Symbol;Acc:MGI:107484]
ENSMUSG00000026482ENSMUST00000111857Rgl131ReverseView as cDNA map |
View as Table
Internal |
Ensembl
ral guanine nucleotide dissociation stimulator,-like 1 [Source:MGI Symbol;Acc:MGI:107484]
ENSMUSG00000026482ENSMUST00000111859Rgl131ReverseView as cDNA map |
View as Table
Internal |
Ensembl
ral guanine nucleotide dissociation stimulator,-like 1 [Source:MGI Symbol;Acc:MGI:107484]
ENSMUSG00000026502ENSMUST00000027783Pppde141ForwardView as cDNA map |
View as Table
Internal |
Ensembl
PPPDE peptidase domain containing 1 [Source:MGI Symbol;Acc:MGI:1926075]
ENSMUSG00000026532ENSMUST00000027817Spna131ForwardView as cDNA map |
View as Table
Internal |
Ensembl
spectrin alpha 1 [Source:MGI Symbol;Acc:MGI:98385]
ENSMUSG00000026556ENSMUST00000027837Vangl231ReverseView as cDNA map |
View as Table
Internal |
Ensembl
vang-like 2 (van gogh, Drosophila) [Source:MGI Symbol;Acc:MGI:2135272]
ENSMUSG00000026556ENSMUST00000111263Vangl231ReverseView as cDNA map |
View as Table
Internal |
Ensembl
vang-like 2 (van gogh, Drosophila) [Source:MGI Symbol;Acc:MGI:2135272]
ENSMUSG00000026586ENSMUST00000027878Prrx111ReverseView as cDNA map |
View as Table
Internal |
Ensembl
paired related homeobox 1 [Source:MGI Symbol;Acc:MGI:97712]
ENSMUSG00000026586ENSMUST00000075805Prrx111ReverseView as cDNA map |
View as Table
Internal |
Ensembl
paired related homeobox 1 [Source:MGI Symbol;Acc:MGI:97712]
ENSMUSG00000026686ENSMUST00000028003Lmx1a21ForwardView as cDNA map |
View as Table
Internal |
Ensembl
LIM homeobox transcription factor 1 alpha [Source:MGI Symbol;Acc:MGI:1888519]
ENSMUSG00000026686ENSMUST00000111377Lmx1a21ForwardView as cDNA map |
View as Table
Internal |
Ensembl
LIM homeobox transcription factor 1 alpha [Source:MGI Symbol;Acc:MGI:1888519]
ENSMUSG00000027520ENSMUST00000029025Zdbf211ForwardView as cDNA map |
View as Table
Internal |
Ensembl
zinc finger, DBF-type containing 2 [Source:MGI Symbol;Acc:MGI:1921134]
ENSMUSG00000027520ENSMUST00000114132Zdbf211ForwardView as cDNA map |
View as Table
Internal |
Ensembl
zinc finger, DBF-type containing 2 [Source:MGI Symbol;Acc:MGI:1921134]
ENSMUSG00000033774ENSMUST00000044180Npbwr111ReverseView as cDNA map |
View as Table
Internal |
Ensembl
neuropeptides B/W receptor 1 [Source:MGI Symbol;Acc:MGI:891989]
ENSMUSG00000033964ENSMUST00000039867Zbtb4111ForwardView as cDNA map |
View as Table
Internal |
Ensembl
zinc finger and BTB domain containing 41 homolog [Source:MGI Symbol;Acc:MGI:2444487]
ENSMUSG00000036104ENSMUST00000037649Rab3gap111ForwardView as cDNA map |
View as Table
Internal |
Ensembl
RAB3 GTPase activating protein subunit 1 [Source:MGI Symbol;Acc:MGI:2445001]
ENSMUSG00000037434ENSMUST00000044954Slc30a111ForwardView as cDNA map |
View as Table
Internal |
Ensembl
solute carrier family 30 (zinc transporter), member 1 [Source:MGI Symbol;Acc:MGI:1345281]
ENSMUSG00000037470ENSMUST00000046875Uggt111ReverseView as cDNA map |
View as Table
Internal |
Ensembl
UDP-glucose glycoprotein glucosyltransferase 1 [Source:MGI Symbol;Acc:MGI:2443162]
ENSMUSG00000037474ENSMUST00000027933Dtl21ReverseView as cDNA map |
View as Table
Internal |
Ensembl
denticleless homolog (Drosophila) [Source:MGI Symbol;Acc:MGI:1924093]
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We gratefully acknowledge support of this work by the William M. Keck Foundation