Takuya Kawamura
Research Associate
Short Bio
Takuya joined Dr. Kirino's Lab in 2016 as a postdoctoral researcher. His research is focused on tRNA functions in cancer cell. He received his Ph.D. from the Ehime University, where he studied tRNA biogenesis in archaea and revealed biosynthesis mechanism of archaeal tRNA modification.
Publications
2024
- Gumas, J, Kawamura, T, Shigematsu, M, Kirino, Y. Immunostimulatory short non-coding RNAs in the circulation of patients with tuberculosis infection. Mol Ther Nucleic Acids. 2024;35 (1):102156. doi: 10.1016/j.omtn.2024.102156. PubMed PMID:38481936 PubMed Central PMC10933579.
2021
- Shigematsu M, Kawamura T, Morichika K, Izumi N, Kiuchi T, Honda S, Pliatsika V, Matsubara R, Rigoutsos I, Katsuma S, Tomari Y, Kirino Y. RNase κ promotes robust piRNA production by generating 2',3'-cyclic phosphate-containing precursors. Nat Commun. 2021 Jul 23;12(1):4498. doi: 10.1038/s41467-021-24681-w. PubMed PMID:34301931.
- Kawamura T, Shigematsu M, Kirino Y. In vitro production and multiplex quantification of 2',3'-cyclic phosphate-containing 5'-tRNA half molecules. Methods. 2021 May 4:S1046-2023(21)00124-9. doi: 10.1016/j.ymeth.2021.04.024. Epub ahead of print. PubMed PMID:33962012.
2019
- Shigematsu, M, Morichika, K, Kawamura, T, Honda, S, Kirino, Y. Genome-wide identification of short 2',3'-cyclic phosphate-containing RNAs and their regulation in aging. PLoS Genet. 2019 Nov 13;15(11):e1008469. doi: 10.1371/journal.pgen.1008469. PubMed PMID:31721758.
2018
- Shigematsu, M, Kawamura, T, Kirino, Y. Generation of 2',3'-Cyclic Phosphate-Containing RNAs as a Hidden Layer of the Transcriptome. Front Genet. 2018;9 :562. doi: 10.3389/fgene.2018.00562. PubMed PMID:30538719 PubMed Central PMC6277466.
2017
- Honda, S, Loher, P, Morichika, K, Shigematsu, M, Kawamura, T, Kirino, Y, Rigoutsos, I, Kirino, Y. Increasing cell density globally enhances the biogenesis of Piwi-interacting RNAs in Bombyx mori germ cells. Sci Rep. 2017;7 (1):4110. doi: 10.1038/s41598-017-04429-7. PubMed PMID:28646211 PubMed Central PMC5482885.
- Honda, S, Kawamura, T, Loher, P, Morichika, K, Rigoutsos, I, Kirino, Y. The biogenesis pathway of tRNA-derived piRNAs in Bombyx germ cells. Nucleic Acids Res. 2017;45 (15):9108-9120. doi: 10.1093/nar/gkx537. PubMed PMID:28645172 PubMed Central PMC5587776.
2016
- Kawamura, T, Hirata, A, Ohno, S, Nomura, Y, Nagano, T, Nameki, N, Yokogawa, T, Hori, H. Multisite-specific archaeosine tRNA-guanine transglycosylase (ArcTGT) from Thermoplasma acidophilum, a thermo-acidophilic archaeon. Nucleic Acids Res. 2016;44 (4):1894-908. doi: 10.1093/nar/gkv1522. PubMed PMID:26721388 PubMed Central PMC4770233.
2014
- Kawamura, T, Anraku, R, Hasegawa, T, Tomikawa, C, Hori, H. Transfer RNA methyltransferases from Thermoplasma acidophilum, a thermoacidophilic archaeon. Int J Mol Sci. 2014;16 (1):91-113. doi: 10.3390/ijms16010091. PubMed PMID:25546389 PubMed Central PMC4307237.
2013
- Hirata, A, Fujishima, K, Yamagami, R, Kawamura, T, Banfield, JF, Kanai, A, Hori, H. X-ray structure of the fourth type of archaeal tRNA splicing endonuclease: insights into the evolution of a novel three-unit composition and a unique loop involved in broad substrate specificity. Nucleic Acids Res. 2012;40 (20):10554-66. doi: 10.1093/nar/gks826. PubMed PMID:22941657 PubMed Central PMC3488258.
2012
- Hirata, A, Fujishima, K, Yamagami, R, Kawamura, T, Banfield, JF, Kanai, A, Hori, H. X-ray structure of the fourth type of archaeal tRNA splicing endonuclease: insights into the evolution of a novel three-unit composition and a unique loop involved in broad substrate specificity. Nucleic Acids Res. 2012;40 (20):10554-66. doi: 10.1093/nar/gks826. PubMed PMID:22941657 PubMed Central PMC3488258.