Welcome to the home page of the Computational Medicine Center at the Sidney Kimmel Medical College of Thomas Jefferson University.
We are a team of interdisciplinary experts who study several categories of short RNA molecules with powerful regulatory roles. These categories include: microRNA (miRNA), miRNA isoforms (isomiRs), transfer RNA (tRNA), tRNA-derived fragments (tRFs), and piRNAs.
Our team has four goals: a) comprehensively elucidate the members of these regulatory categories across tissues; b) understand what these regulators do and how they do it; c) unravel the links of these regulators to homeostasis and disease; and, d) translate the generated knowledge into novel, powerful, and individualized diagnostics, prognostics, and therapies (“Precision Medicine”).
Computational Medicine Center