News
A hormone-dependent tRNA half drives cell cycle progression by destabilizing p21 mRNA
When cells receive growth cues, they must carefully balance pro-proliferative signals with “brakes” that prevent uncontrolled division. In hormone-dependent cancers,…
New ALS Biomarkers Discovered for Prognosis and Diagnosis
In our paper “Re-Analyses of Samples From Amyotrophic Lateral Sclerosis Patients and Controls Identify Many Novel Small RNAs With Diagnostic…
Phillipe Loher receives President’s Award for Trailblazing in AI and Machine Learning
Update from University President Dr. Aldridge on Thomas Jefferson University Weekly Update (5/16/24): “Congratulations to Phillipe Loher, Director of Machine…
MINRbase: database for ribosomal RNA-derived fragments (rRFs)
5′-tRNA Half Molecules Providing Insights on TLR7 Activation
Toll-like receptor 7 (TLR7) is a vital component of the innate immune system, which also identifies single-stranded RNAs (ssRNAs) as…
Newly-identified molecules derived from ribosomal RNA that can potentially combat tuberculosis infection
Jefferson’s Nexus highlights the CMC’s findings on Y RNA fragments (yRFs) in the platelets of healthy individuals and COVID patients
An article published in this month’s Nexus discusses the CMC team’s recent discovery that Y RNA fragments (“yRFs”) are the…


