RNase κ promotes piRNA production by generating 2′,3′-cyclic phosphate (cP-RNA) precursors
In our new publication [1], we show that cP-RNAs serve as piRNA precursors in mouse and silkworm. A mitochondria-associated endoribonuclease,… In our new publication [1], we show that cP-RNAs serve as piRNA precursors in mouse and silkworm. A mitochondria-associated endoribonuclease,… In vitro production and multiplex quantification of 2′,3′-cyclic phosphate-containing 5′-tRNA half molecules
We synthesized cP-containing 5′-tRNA half molecules and developed a multiplex TaqMan RT-qPCR method which can simultaneously quantify multiple cP-containing 5′-tRNA… Oxidative stress enhances the expression of 2′,3′-cyclic phosphate-containing RNAs (cP-RNAs)
By using our original cP-RNA-seq, we have revealed comprehensive expression profiles of 2′,3′-cyclic phosphate-containing RNAs (cP-RNAs) in human cells and… First genome-wide identification of short cyclic phosphate-containing RNAs
Our comprehensive identification of 2′,3′-cyclic phosphate-containing RNAs (cP-RNAs) unraveled a novel, abundant class of non-coding RNAs which may play a… 5′-terminal nucleotide variations in human cytoplasmic tRNAHisGUG and its 5′-halves
We clarified 5′-end variations of human cytoplasmic tRNAHisGUG and its 5′-halves, providing insights into tRNAHisGUG maturation and the regulation of…