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Home Archive by category "Research Papers" (Page 3)

Research Papers

Summaries of our highlighted papers.

The roles of GPRC5A in pancreatic ductal adenocarcinoma

Illustration Showing the Roles of GPRC5A in Pancreatic Ductal Adenocarcinoma We found GPRC5A is a potential oncogene in pancreatic ductal adenocarcinoma cells that is upregulated by gemcitabine with help from…

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Research Papers

miRNA isoforms in the breast cancer context

Graphic comparison of the tumor clusters formed when analyzing miRNAs or the full set of isomiRs Transcending the one-locus-one-miRNA paradigm deepens the understanding of cancer biology and racial health disparities1 MiRNA isoforms (isomiRs) are molecules produced…

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Research Papers

Expanding the repertoire of tRNA-derived fragments

Distribution of Starting Position and Lengths for i-tRFs for LCL and BRCA Data Sets Analysis of RNA sequencing data from more than 700 people multiplies the catalogue of tRFs and reveals dependencies on race,…

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Research Papers

Non-standard regulation of DNA damage repair by miRNAs

Sketch showing the targeting site of miR-15/107 family on BRCA1 The miR-15/107 group of miRNAs regulate BRCA1 expression in a tissue-specific manner through a novel target site in its coding…

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Research Papers

SHOT-RNAs promote cell growth in cancers

SHOT-RNAs promote cell growth in cancers We discovered that a novel type of tRNA-derived small RNA, termed SHOT-RNA, is specifically expressed in ER/AR-positive breast and prostate…

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Research Papers

FL-PCR for quantification of mature tRNAs

Four-Leaf clover qRT-PCR (FL-PCR) Four-leaf clover qRT-PCR: A convenient method for selective quantification of mature tRNA1 Transfer RNAs (tRNAs) play a central role in translation…

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Research Papers

Db-PCR for quantification of RNA variants

Graphic description of the Dumbbell-PCR (Db-PCR) method for quantification of RNA variants Dumbbell-PCR: a method to quantify specific small RNA variants with a single nucleotide resolution at terminal sequences Recent advances in…

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Research Papers

piRNA biogenesis on mitochondria

Sketch of mitochondrial protein BmPAPI modulating the length of mature piRNAs Mitochondrial protein BmPAPI modulates the length of mature piRNAs[1] piRNAs are the 24-31 nucleotides small RNAs that are specifically and…

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Research Papers

Long RNAs in Human Platelets

Analysis of multiple individuals shows extensive differences between the platelet transcriptome and the platelet proteome [1]. The data mentioned in…

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Research Papers
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