YAMAT-seq: an efficient method for high-throughput sequencing of mature tRNAs
We developed YAMAT-seq, an efficient method for tRNA sequencing, which provides high-throughput technique for identifying tRNA profiles and their regulations… Research Papers
Summaries of our highlighted papers.
We developed YAMAT-seq, an efficient method for tRNA sequencing, which provides high-throughput technique for identifying tRNA profiles and their regulations… 5′-terminal nucleotide variations in human cytoplasmic tRNAHisGUG and its 5′-halves
We clarified 5′-end variations of human cytoplasmic tRNAHisGUG and its 5′-halves, providing insights into tRNAHisGUG maturation and the regulation of… Post-transcriptional regulation of BRCA2 through interactions with miR-19a and miR-19b
Our results suggest that BRCA2 is post-transcriptionally regulated by miR-19a and miR-19b, two members of the miR-17/92 cluster, and that… The roles of GPRC5A in pancreatic ductal adenocarcinoma
We found GPRC5A is a potential oncogene in pancreatic ductal adenocarcinoma cells that is upregulated by gemcitabine with help from… miRNA isoforms in the breast cancer context
Transcending the one-locus-one-miRNA paradigm deepens the understanding of cancer biology and racial health disparities1 MiRNA isoforms (isomiRs) are molecules produced… Expanding the repertoire of tRNA-derived fragments
Analysis of RNA sequencing data from more than 700 people multiplies the catalogue of tRFs and reveals dependencies on race,… Non-standard regulation of DNA damage repair by miRNAs
The miR-15/107 group of miRNAs regulate BRCA1 expression in a tissue-specific manner through a novel target site in its coding… SHOT-RNAs promote cell growth in cancers
We discovered that a novel type of tRNA-derived small RNA, termed SHOT-RNA, is specifically expressed in ER/AR-positive breast and prostate… FL-PCR for quantification of mature tRNAs
Four-leaf clover qRT-PCR: A convenient method for selective quantification of mature tRNA1 Transfer RNAs (tRNAs) play a central role in translation… Db-PCR for quantification of RNA variants
Dumbbell-PCR: a method to quantify specific small RNA variants with a single nucleotide resolution at terminal sequences Recent advances in…